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  Vascular endograftUSPTO Application #: 20060184228Title: Vascular endograft Abstract: An endograft for a vessel having a vascular branch extending from the vessel is provided. The endograft includes a main body having a wall separating interior and exterior surfaces and adapted to be inserted within the vessel. The main body is characterized by a single proximal opening and a single terminal opening and at least one aperture extending through the wall. At least one stent is secured to the main body that upon expansion pressure fits the main body into the vessel. An open tunnel is secured to the interior surface of the main body around the main body aperture and secured somewhere along the tunnel length to provide fluid communication between the interior and exterior surfaces of the main body through the aperture and with the vascular branch in proximity to the main body aperture. The tunnel is readily formed independent of an expandable stent. Through the addition of further apertures and tunnels, an endograft is well suited for revascularizing the superior mesenteric artery and renal arteries for the treatment of a suprarenal aortic aneurysm. The insertion of a sleeve positioned partly within the tunnel and extending beyond the exterior surface of the main body into the vascular branch assures continued fluid flow to the vascular branch. (end of abstract) Agent: Gifford, Krass, Groh, Sprinkle & Citkowski, P.c - Troy, MI, US Inventor: Michael D. Khoury USPTO Applicaton #: 20060184228 - Class: 623001130 (USPTO) Related Patent Categories: Prosthesis (i.e., Artificial Body Members), Parts Thereof, Or Aids And Accessories Therefor, Arterial Prosthesis (i.e., Blood Vessel), Stent In Combination With Graft The Patent Description & Claims data below is from USPTO Patent Application 20060184228. Brief Patent Description - Full Patent Description - Patent Application Claims
RELATED APPLICATION [0001] This application claims priority of U.S. Provisional Patent Application Ser. No. 60/653,793 filed Feb. 17, 2005, which is incorporated herein by reference. FIELD OF THE INVENTION [0002] The present invention in general relates to a vascular endograft and method for surgical deployment thereof, and in particular to a vascular endograft facilitating revascularizing branching vessels. BACKGROUND OF THE INVENTION [0003] Stent grafts have become a popular treatment option for aneurysms. Typically, a stent graft is delivered to a treatment site through endovascular insertion via an introducer or catheter. Subsequent radial expansion retains the graft in position relative to the vessel wall. In instances where an aneurysm is located along a length of vessel on which branch vessels are not present, a simple tubular cylindrical stent graft is suitable. Additionally, stent grafts are known to the art for treatment of aneurysms in aortic regions where the distal end of the graft bifurcates to define two lumens so as to extend into arterial branches. Such bifurcated stent grafts are well known for the treatment of ascending thoracic and abdominal aortic aneurysms. Exemplary stents of this kind are embodied in U.S. Pat. Nos. 6,695,875 B2 and 6,814,752 B1 and U.S. Patent Application Publication 2004/0230287 A1. [0004] Currently, aneurysms in certain anatomic regions of the aorta have proved difficult to properly repair with a stent graft. In particular, treatment of suprarenal aortic aneurysms has proved problematic. In such locales, the lack of a neck above the aneurysm precludes attachment of a conventional endovascular graft. Additionally, in the treatment of an aneurysm in such a locale, the preoperative measurement of arterial and aortic dimensional variables necessary to form a suitable endograft has proven to be complex. Any misfit in preparing a conventional stent graft to treat an aneurysm in this region results in lumenal obstruction or collapse, or material fatigue, resulting in continued blood flow into the aneurysm. [0005] WO 03/082153, FIGS. 7-11, is representative of the stent grafts for the treatment of suprarenal aortic aneurysms. This graft includes a single lumen containing a Gianturco type zigzag Z stent tube in communication at a distal end with an aperture in the lumen and free floating at the proximal end within the lumen. Unfortunately, the free-floating tube proximal end is prone to damage during insertion of a sleeve therefrom into an artery in registry with the aperture, as well as under hemodynamic operating conditions. [0006] Thus, there exists a need for a vascular endograft capable of treating an aneurysm in a vessel having adjacent vessel branches. SUMMARY OF THE INVENTION [0007] An endograft for a vessel having a vascular branch extending from the vessel is provided. The endograft includes a main body having a wall separating interior and exterior surfaces and adapted to be inserted within the vessel. The main body is characterized by a single proximal opening and a single terminal opening and at least one aperture extending through the wall. At least one stent is secured to the main body that upon expansion pressure fits the main body into the vessel. An open tunnel is secured to the interior surface of the main body around the main body aperture and secured somewhere along the tunnel length to provide fluid communication between the interior and exterior surfaces of the main body through the aperture and with the vascular branch in proximity to the main body aperture. The tunnel is readily formed independent of an expandable stent. Through the addition of further apertures and tunnels, an endograft is well suited for revascularizing the celiac, superior mesenteric artery and renal arteries for the treatment of a suprarenal aortic aneurysm. The insertion of a sleeve positioned partly within the tunnel and extending beyond the exterior surface of the main body into the vascular branch assures continued fluid flow to the vascular branch. BRIEF DESCRIPTION OF THE DRAWINGS [0008] FIG. 1 is a plan view of an inventive endograft depicted within a partial cutaway of the superior mesenteric and renal artery region of the descending aorta; [0009] FIG. 2 is a top view of the inventive stent graft depicted in FIG. 1 absent the expandable stents for visual clarity; [0010] FIG. 3 is a magnified cross-sectional view through a tunnel connecting the endograft depicted in FIG. 1 to the superior mesenteric artery and containing a sleeve therein; [0011] FIG. 4 is a plan view of an inventive endograft proportioned and apertured for revascularization of the celiac, superior mesenteric, and two renal arteries, the tunnels are depicted interior to the endograft as dashed lines; the expandable Z stents are not shown for visual clarity; and [0012] FIGS. 5A-5D are a schematic depiction of a possible surgical process for revascularizing celiac, superior mesenteric, and renal arteries, as part of the deployment of an inventive endograft to treat a suprarenal aortic aneurysm. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS [0013] The present invention has utility as a vascular endograft well suited for the treatment of aneurysms. While the present invention is detailed herein with respect to an endograft having revascularization tunnels positioned for use in the aortic region encompassing the superior mesenteric artery (SMA) and renal arteries, it is appreciated that an inventive endograft has application in a variety of vascular settings where vessels branch from a main lumen. In addition, the inventive endograft is appreciated to be suitable for the treatment of an aneurysm alone, or in combination with a conventional stent graft depending upon the relative position and size of a vascular aneurysm. [0014] An inventive endograft has a main body including at least one deployable, expanding stent and an open tunnel secured within the main body to a main body sidewall aperture to ensure reliable fluid communication between fluid passing through the main body and a vascular branch overlying an open tunnel terminus. The tunnel is secured somewhere along the tunnel length to the interior of the main body and lacks a stent expander along the length thereof. Preferably, the tunnel is secured to the main body along the majority of the tunnel length. Through the use of a sleeve that extends from the tunnel into the overlying vascular branch, a predefined percentage of the fluid flow through the main body of an inventive endograft is shunted into the vascular branch. While an open tunnel used in an inventive endograft is cylindrical in general shape in a first embodiment, it is appreciated that a bifurcated tunnel having an inverted "Y" shape is operative in situations where vascular branch bifurcates proximal to the central vessel are desired to have assured fluid flow. [0015] The present invention is further illustrated with respect to the following non-limiting embodiments depicted in the figures. Referring now to FIGS. 1-3, an inventive endograft is shown generally at 10. The endograft 10 has a main body 12 having at least one proximal opening 14 and at least one distal opening 16. As used herein, it is appreciated that proximal and distal are defined relative to the direction of fluid flow through the vessel lumen in which an inventive endograft is secured. At least one stent 18 is secured about the circumference of the main body 12 on the external surface 20 of the main body wall 15. A Gianturco zigzag stent is representative of stent types operative herein. The main body 12 has an interior surface 22 through which fluid communication within the vessel is maintained. An open tunnel 24 has a mouth 26 and a terminus 28. The tunnel 24 is formed of a material that will not become obstructed or collapse under prolonged exposure to physiologic fluid transport. Materials suitable for the construction of a main body 12 and a tunnel 24 independently in each case include polymeric materials such as those sold under the trade names Dacron.RTM., Gortex.RTM., Teflon.RTM. and implant grade silicones. In order to preclude obstruction and/or collapse of a tunnel 24 subsequent to placement, the tunnel 24 is formed independent of an extendable stent associated with the tunnel circumference. The terminus 28 of the tunnel 24 is sealed around an aperture 30 within the main body 12 and is flush with the exterior surface 20. As a result, the tunnel 24 does not extend beyond the dimensions of the main body 12; this attribute facilitates placement of an inventive endograft 10 within the central vessel denoted at V. The aperture 30 and terminus 28 of the tunnel 24 are positioned within the main body 12 so as to overlie a vascular branch B extending from the vessel V in which the main body 12 is placed. The tunnel 24 is secured to the interior surface 22 at at least one point along the tunnel length. A single point securement is ideally proximal to the mouth 28. Preferably, the tunnel is secured along the majority of the tunnel length. More preferably, the entire tunnel length is secured to the interior surface 22. Securement of the tunnel 24 to the interior surface 22 is accomplished with conventional fastening techniques illustratively including sutures, contact adhesives, sonic welding, thermal welding, and combinations thereof. A securement anchoring the tunnel 24 to the interior surface 22 is critical to the longevity of an inventive endograft in assuring that the tunnel 24 does not kink during placement or under the strong pulsatile flow dynamics experienced within the aorta. It is appreciated that each vascular branch requiring perfusion that overlies an inventive endograft is provided with an open tunnel as described herein to assure fluid communication therewith. [0016] With an inventive endograft 10 placed within a vessel V, fluid communication with a vascular branch B is provided through the placement of a separate sleeve 32 in part within the tunnel 24 and extending beyond the terminus 28 into the vascular branch B as shown in FIG. 3. A sleeve 32 is conventional to the art and typically is formed of materials such as those used for the formation of the main body 12 or the tunnel 24. A sleeve 32 typically includes multiple circumferential stents 34 in order to retain the sleeve 32 in a preselected position relative to the tunnel 24 and the vascular branch B. [0017] The inventive embodiment depicted in FIGS. 1-3 corresponds to an endograft spanning the suprarenal portion of the aorta and as such the vessel V is the aorta and the vascular branch B is the superior mesenteric artery. The additional vascular branches depicted at C and D correspond to the right and left renal arteries, respectively. As blood flow to the renal arteries C and D must necessarily be maintained in a successful aneurysm treatment, tunnel 24' is placed within the main body 12 in order to assure fluid communication between the aorta and the right renal artery C, where like primed numerals correspond to those detailed above with respect to tunnel 24. Tunnel 24 is secured to the interior surface 22 as detailed above with respect to tunnel 24. The left renal artery D is depicted with the uncommon phenotype of an immediate bifurcation in order to illustrate that a bifurcated tunnel 36 optionally replaces a cylindrical tunnel as depicted with reference to numeral 24 in instances where patient anatomy so dictates. Bifurcated tunnel 36 has a mouth 38 of a preselected diameter and a bifurcation 40 so as to define a first terminus 42 and a second terminus 44. The termini 42 and 44 are sealed to apertures 46 and 48 formed through the wall 15 of the main body 12. Tunnel 36 is secured to the interior surface 22 as detailed above with respect to tunnel 24. Sleeves 50 and 52 are similar to sleeve 32 as described with respect to tunnel 24 and serve to assure a preselected percentage of blood flow to each of the left renal arterial branches. [0018] It is appreciated that the relative percentage of fluid exiting through an inventive tunnel relative to the percentage of fluid exiting the distal opening of an inventive endograft is controlled by the effective diameter of the tunnel as compared to the endograft diameter at the position of the tunnel mouth. The effective diameter of an inventive tunnel is appreciated to be equivalent to the internal diameter of the tunnel mouth in the theoretical instance where the tunnel wall and sleeve are of infinitesimal thickness. Actual flow to a vascular branch is readily modeled with standard fluid dynamic equations. In the embodiment depicted in FIGS. 1-3, tunnels 24, 24' and 36 have lengths ranging from 10 to 25 millimeters with each tunnel having a diameter of from between 6 and 12 millimeters. The internal surface diameter at the proximal opening 14 is typically between 35 and 45 millimeters while the internal diameter about the distal opening 16 ranges from 20 to 30 millimeters. The overall length of the endograft 10 for an adult human ranges from 60 to 120 millimeters. While the above dimensional ranges associated with an inventive endograft 10 are those associated with a suprarenal endograft for an adult human subject, it is appreciated that human child, veterinary endografts, as well as those used to treat differently positioned aneurysms within an adult human, or to accommodate peculiar subject anatomy will vary in any, or all of these dimensions. Continue reading... Full patent description for Vascular endograft Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Vascular endograft patent application. ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. 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