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12/14/06 - USPTO Class 514 |  56 views | #20060281668 | Prev - Next | About this Page  514 rss/xml feed  monitor keywords

Vascular disease therapies

Title: Vascular disease therapies


Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), Peptide Containing (e.g., Protein, Peptones, Fibrinogen, Etc.) Doai

Brief Patent Description - Full Patent Description - Patent Claims

The Patent Description & Claims data below is from USPTO Patent Application 20060281668, Vascular disease therapies.


1. A method for improving vascular function in a subject, the method comprising administering to the subject an effective amount of an anti-CTGF agent, thereby improving vascular function in the subject.

2. The method of claim 1, wherein the vascular function is microvascular function.

3. The method of claim 1, wherein the vascular function is macrovascular function.

4. The method of claim 1, wherein the vascular function is associated with peripheral vasculature.

5. The method of claim 1, wherein the improving comprises reducing endothelium dysfunction..

6. The method of claim 1, wherein the improving comprises reducing arterial stiffness.

7. The method of claim 6, wherein the arterial stiffness is selected from the group consisting of axial arterial stiffness, radial arterial stiffness, and circumferential arterial stiffness.

8. The method of claim 1, wherein the improving comprises reducing vascular permeability.

9. The method of claim 1, wherein the improving comprises reducing extravasation.

10. The method of claim 1, wherein the improving comprises reducing intima-media thickening.

11. The method of claim 10, wherein the intima-media thickening is common carotid artery intima-media thickening.

12. The method of claim 1, wherein the improving comprises reducing edema.

13. The method of claim 12, wherein the edema is tissue edema.

14. The method of claim 1, wherein the improving comprises reducing damage to blood vessels.

15. The method of claim 1, wherein the improving comprises reducing vascular calcification.

16. The method of claim 1, wherein the subject is a subject having or at risk for having diabetes.

17. The method of claim 1, wherein the subject is a mammalian subject.

18. The method of claim 1, wherein the subject is a human subject.

19. A method for treating or preventing a vascular complication of diabetes in a subject, the method comprising administering to the subject an effective amount of an anti-CTGF agent, thereby treating or preventing the vascular complication of diabetes.

Brief Patent Description - Full Patent Description - Patent Claims

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Previous Patent Application:
Cardiovascular disease therapies
Next Patent Application:
Method and compositions for the treatment of diabetes and related complications
Industry Class:
Drug, bio-affecting and body treating compositions

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