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09/18/08 - USPTO Class 514 | 25 views | #20080227850 | Prev - Next | About this Page

Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms

Title: Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms

Brief Patent Description - Full Patent Description - Patent Claims

The Patent Description & Claims data below is from USPTO Patent Application 20080227850, Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms.

1. A method for treating or preventing vasomotor symptoms in a subject in need thereof, comprising the step of: administering to said subject a therapeutically effective amount of at least one dual NRI/SRI compound or pharmaceutically acceptable salt thereof, wherein said amount is less than about 37.5 mg/day.

2. A method according to claim 1, wherein said amount is less than about 30 mg/day.

3. A method according to claim 1, wherein said amount is less than about 25 mg/day.

4. A method according to claim 1, wherein said amount is less than about 20 mg/day.

5. A method according to claim 1, wherein said amount is less than about 15 mg/day.

6. A method according to claim 1, wherein said amount is less than about 10 mg/day.

7. A method according to claim 1, wherein said amount is less than about 5 mg/day.

8. A method according to claim 1, wherein said dual NRI/SRI compound is a compound selected from the group consisting of venlafaxine, O-desmethyl-venlafaxine, duloxetine, and combinations and pharmaceutically acceptable salts thereof.

9. A method according to claim 1, wherein said dual NRI/SRI compound is venlafaxine or a pharmaceutically acceptable salt thereof.

10. A method according to claim 1, wherein said dual NRI/SRI compound is O-desmethyl-venlafaxine or a pharmaceutically acceptable salt thereof.

11. A method according to claim 1, wherein said dual NRI/SRI compound is duloxetine or a pharmaceutically acceptable salt thereof.

12. A method according to claim 1, wherein said vasomotor symptom is hot flush.

13. A method according to claim 1, wherein said vasomotor symptom is caused by a thermoregulatory dysfunction.

14. A method according to claim 1, wherein said subject is human.

15. A method according to claim 14, wherein said human is a female.

16. A method according to claim 15, wherein said female is pre-menopausal.

17. A method according to claim 15, wherein said female is peri-menopausal.

18. A method according to claim 15, wherein said female is post-menopausal.

19. A method according to claim 14, wherein said human is a male.

20. A method according to claim 19, wherein said male is naturally, chemically or surgically andropausal.

Brief Patent Description - Full Patent Description - Patent Claims

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