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Use of modified extracellular matrix proteins in diagnosis and treatment of atherosclerosis

Abstract: The present invention relates to the use of fibronectin, tenascin, collagens type I, III, VI and/or VIII modified by aldehyde or by glycosylation in ELISA for detection of antibodies in plasma and serum to diagnose atherosclerosis as well as the use of induction of tolerance and active as well as passive immunization against glycosylated or aldehydemodified fibronectin, tenascin, collagen type I, III, VI and/or VIII for prevention and treatment of atherosclerosis. ...

Agent: Gauthier & Connors LLP - Boston, MA, US
Inventor: Jan Nilsson
USPTO Applicaton #: #20070104725 - Class: 424185100 (USPTO) - 05/10/07 - Class 424
Related Terms: ELISA Elisa Fibronectin Glycosylated Nasc

Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Antigen, Epitope, Or Other Immunospecific Immunoeffector (e.g., Immunospecific Vaccine, Immunospecific Stimulator Of Cell-mediated Immunity, Immunospecific Tolerogen, Immunospecific Immunosuppressor, Etc.), Amino Acid Sequence Disclosed In Whole Or In Part; Or Conjugate, Complex, Or Fusion Protein Or Fusion Polypeptide Including The Same
The Patent Description & Claims data below is from USPTO Patent Application 20070104725, Use of modified extracellular matrix proteins in diagnosis and treatment of atherosclerosis.

ELISA Elisa Fibronectin Glycosylated Nasc

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