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updated 05/17/13

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Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor

Abstract: A method for the direct treatment towards the specific sites of a disease is disclosed. This method is based on the delivery of proteins by catheterization to discrete blood vessel segments using genetically modified or normal cells or other vector systems. Endothelial cells expressing recombinant therapeutic agent or diagnostic proteins are situated on the walls of the blood vessel or in the tissue perfused by the vessel in a patient. This technique, provides for the transfer of cells or vectors and expression of recombinant genes in vivo and allows the introduction of proteins of therapeutic or diagnostic value for the treatment of diseases. ...

Agent: Brinks Hofer Gilson & Lione - Chicago, IL, US
Inventors: Elizabeth G. Nabel, Gary J. Nabel
USPTO Applicaton #: #20070287682 - Class: 514044000 (USPTO) - 12/13/07 - Class 514
Related Terms: Blood Vessel C Protein Catheter Catheterization Endothelial Endothelial Cell F Protein Genetic Genetically In Vivo Recombinant

Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), O-glycoside, , Nitrogen Containing Hetero Ring, Polynucleotide (e.g., Rna, Dna, Etc.)
The Patent Description & Claims data below is from USPTO Patent Application 20070287682, Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor.

Blood Vessel C Protein Catheter Catheterization Endothelial Endothelial Cell F Protein Genetic Genetically In Vivo Recombinant

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