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06/22/06 - USPTO Class 700 |  147 views | #20060136081 | Prev - Next | About this Page  700 rss/xml feed  monitor keywords

Pharmaceutical compounder and information management system

USPTO Application #: 20060136081
Title: Pharmaceutical compounder and information management system
Abstract: Information management systems and methods can be used with at least one pharmaceutical compounding device. The systems and methods comprise a controller coupled to the compounding device. A compounding control manager resides on the controller to receive compounding order input and generate control commands to the compounding device based, at least in part, upon the compounding order input. An order process control manager is in data communication with the compounding control manager to communicate compounding order input to the compounding control manager. The order entry process manager includes an order function for receiving entry of compounding order input through a browser-based interface. The browser-based interface can include an order entry workstation separate from the compounding device, or a network of order entry workstations separate from the compounding device, or can reside on the controller. (end of abstract)



Agent: Ratnerprestia - Valley Forge, PA, US
Inventors: Aleandro DiGianfilippo, Richard R. Pierce
USPTO Applicaton #: 20060136081 - Class: 700095000 (USPTO)

Related Patent Categories: Data Processing: Generic Control Systems Or Specific Applications, Specific Application, Apparatus Or Process, Product Assembly Or Manufacturing

Pharmaceutical compounder and information management system description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20060136081, Pharmaceutical compounder and information management system.

Brief Patent Description - Full Patent Description - Patent Application Claims
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RELATED APPLICATIONS

[0001] This application is a Divisional application of U.S. application Ser. No. 10/335,552, filed Dec. 31, 2002 which claimed the benefit of priority of U.S. Provisional Application No. 60/344,869, filed Dec. 31, 2001.

FIELD OF THE INVENTION

[0002] This invention relates to systems and methods for compounding of liquids and/or drugs intended to be administered to a human being or an animal.

BACKGROUND OF THE INVENTION

[0003] Pharmaceutical compounding involves the transfer of two or more of individual prescribed liquids and/or drugs from multiple source containers into a single collecting container, for the purpose of administering the mix of liquids and/or drugs intravenously to an individual in need. Presently, the pharmaceutical compounding of liquids and/or drugs takes place primarily at one of three sites. These are: (1) hospital based compounding performed by pharmacists or pharmacy technicians in the hospital pharmacy; (2) alternate site based compounding performed primarily by pharmacists or pharmacy technicians in the home care company pharmacy; and (3) compounding centers operated by any one of several major pharmaceutical or hospital supply companies.

[0004] The operational and performance demands upon these compounding systems and methodologies are becoming increasingly more complex and sophisticated, in terms of, e.g., safety, speed, reliability, accuracy, and overall user friendliness and ergonomics. The operational and performance demands upon these compounding systems and methodologies are also becoming increasingly more complex and sophisticated with regard to the management of patient and prescription information, in terms of providing an information path that starts with the clinician and finishes with the final product delivery to the end patient.

SUMMARY OF THE INVENTION

[0005] One aspect of the invention provides information management systems and methods adapted to be used with at least one pharmaceutical compounding device. The systems and methods comprise a controller coupled to the compounding device. A compounding control manager resides on the controller to receive compounding order input and generate control commands to the compounding device based, at least in part, upon the compounding order input. An order process control manager is in data communication with the compounding control manager to communicate compounding order input to the compounding control manager. The order entry process manager includes an order function for receiving entry of compounding order input through a browser-based interface.

[0006] The browser-based interface can include an order entry workstation separate from the compounding device, or a network of order entry workstations separate from the compounding device, or can reside on the controller.

[0007] The order entry process manager can include a database function for retaining the compounding order input in memory, a printing function for generating printable output, e.g., labeling, based, at least in part, upon the compounding order input, or a report function for generating reporting output based, at least in part, upon the compounding order input.

[0008] Another aspect of the invention provides a pharmaceutical compounding device that comprises at least one pump element, a controller coupled to the pumping element, and a compounding control manager residing on the controller to receive compounding order input and generate control commands to the pump element based, at least in part, upon the compounding order input. According to this aspect of the invention, the compounding control manager includes a verification function that requires a prescribed bar code input before generation of the control commands. The bar code input can include, e.g., a source solution identification, and/or a source solution lot number, and/or a source solution expiration date.

[0009] Another aspect of the invention provides an interface for performing a pharmaceutical compounding procedure using a compounding device. The interface comprises a controller coupled to the compounding device, a display screen coupled to the controller, and a compounding control manager residing on the controller to receive compounding order input and generate control commands to the compounding device based, at least in part, upon the compounding order input. According to this aspect of the invention, the compounding control manager includes a graphical user interface generated on the display screen that includes at least one touch-screen function for receiving compounding order input. The touch-screen function can affect, e.g., the selection of a source solution, or the selection of an amount of liquid to be transferred. The compounding control manager can also include a help function executed through the graphical user interface, or an informational video executed through the graphical user interface.

[0010] Another aspect of the invention provides an interface for performing a pharmaceutical compounding procedure using a compounding device. The interface comprises a controller coupled to the compounding device, a display screen coupled to the controller, and a compounding control manager residing on the controller to receive compounding order input and generate control commands to the compounding device based, at least in part, upon the compounding order input. According to this aspect of the invention, the compounding control manager includes at least one informational video displayable on the display screen.

[0011] Another aspect of the invention provides a pharmaceutical compounding device that comprises a driver and a drive shaft coupled to the driver for rotation. The drive shaft extends along a first axis. The device also includes an idler shaft that extends along a second axis offset from the first axis. A peristaltic pump rotor is carried on the idler shaft. A drive gear is carried on the drive shaft and coupled to the peristaltic pump rotor. A clutch assembly is carried on the drive shaft and coupled to the drive gear. The clutch assembly is operable in a first mode to disengage the drive gear from the drive shaft and a second mode to engage the drive gear with the drive shaft. The clutch assembly thereby selectively imparts rotation of the drive shaft to the peristaltic pump rotor.

[0012] Another aspect of the invention provides a fluid transfer set. The set comprises first transfer tubing, second transfer tubing, and a manifold that joins the first transfer tubing and second transfer tubing in flow communication. A first one way valve is in-line in the first transfer tubing to allow fluid flow in the first transfer tubing toward the manifold but not in an opposite direction. The first one-way valve has a first cracking pressure. A second one way valve is in-line in the second transfer tubing to allow fluid flow in the second transfer tubing toward the manifold but not in an opposite direction. The second one-way valve has a second cracking pressure different than the first cracking pressure. When used in pharmaceutical compounding, the transfer set can mediate lipid hazing.

[0013] Other features and advantages of the inventions are set forth in the following specification and attached drawings.

BRIEF DESCRIPTION OF THE DRAWINGS

[0014] FIG. 1 is a perspective view of a pharmaceutical compounding system that includes a compounding device that, in use, mixes or compounds two or more selected liquids and/or drugs intended to be administered to a human being or an animal.

[0015] FIG. 2A is a view of a disposable transfer set that can be used in association with the compounding device shown in FIG. 1.

[0016] FIGS. 2B and 2C are enlarged views, partially broken away and in section, of an embodiment of a manifold that the transfer set shown in FIG. 2A can incorporate to mediate against lipid hazing.

[0017] FIGS. 2D and 2E are enlarged views, partially broken away and in section, of another embodiment of a manifold that the transfer set shown in FIG. 2A can incorporate to mediate against lipid hazing.

[0018] FIG. 2F is a view of a portion of the disposable transfer set shown in FIG. 2A, which includes a transfer tube organizer to facilitate use of the transfer set with the compounding device shown in FIG. 1.

[0019] FIG. 3 is a perspective view of the system shown in FIG. 1 with the transfer set shown in FIG. 2A mounted for use on the compounding device.

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