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Organic compounds -- part of the class 532-570 series

Below are recently published patent applications awaiting approval from the USPTO. Recent week's RSS XML file available below.
Listing for abstract view: USPTO application #, Title, Abstract excerpt,Patent Agent. Listing format for list view: USPTO National Class full category number, title of the patent application.
01/22/2015 > 5 patent applications in 5 patent subcategories.

20150025230 - Single nucleotide polymorphisms in brca1 and cancer risk: The invention provides methods for identifying mutations, such as single nucleotide polymorphisms (SNPs), within breast and ovarian cancer associated genes that modify the binding efficacy of microRNAs (miRNAs). In a preferred embodiment, methods of the invention identify a SNP that decreases expression of the BRCA1 gene by increasing or decreasing... Agent: Yale University

20150025231 - Compositions and methods for modulation of ikbkap splicing: The present disclosure provides compounds comprising oligonucleotides complementary to a portion of the IKBKAP gene. Certain such compounds are useful for hybridizing to a portion of the IKBKAP gene, including but not limited to a portion of the IKBKAP gene in a cell. In certain embodiments, such hybridization results in... Agent: Isis Pharmaceuticals, Inc.

20150025232 - Heptamer-type small guide nucleic acids inducing apoptosis of human leukemia cells: There is provided a heptamer-type small guide nucleic acid that comprises any of the 7-base sequences of SEQ ID NOS: 1 to 15, and induces apoptosis of human leukemia cells. A leukemia therapeutic agent containing the heptamer-type small guide nucleic acid as an active ingredient is also provided. The novel... Agent:

20150025233 - Use of lipid conjugates in the treatment of diseases: wherein L is a lipid or a phospholipid, Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol, Y is either nothing or a spacer group ranging in length from 2 to 30 atoms, X is a polymer; and n is a number from 1 to 1000, wherein any bond... Agent:

20150025234 - Ganglioside compositions: The invention provides novel gangliosides and mixtures of novel gangliosides, and drug products containing the same. The invention also provides cells induced to over-express one or more gangliosides. The invention further provides methods for production of gangliosides, e.g., GM1, from cells in culture using, for example, bone marrow cells and... Agent: Garnet Biotherapeutics, Inc.

01/15/2015 > 5 patent applications in 4 patent subcategories.

20150018537 - Process for perparing fondaparinux sodium and intermediates useful in the synthesis thereof: Processes for the synthesis of the Factor Xa anticoagulent Fondaparinux, and related compounds are described. Also described are protected pentasaccharide intermediates as well as efficient and scalable processes for the industrial scale production of Fondaparinux sodium by conversion of the protected pentasaccharide intermediates via a sequence of deprotection and sulfonation... Agent: Reliable Biopharmaceutical Corporation

20150018538 - Method and device for marking articles: Provided are a method and device for marking an article for security, tracking or authentication. The method includes depositing a solution comprising a nucleic acid marker onto at least a portion of the article. The nucleic acid marker may be activated, for example, by adding a functional group to the... Agent:

20150018539 - Modified mirna as a scaffold for shrna: What is described is a modified miRNA molecule for producing an artificial siRNA/mature small RNA molecule that inhibits the expression of a target transcript of a host cell, comprising a stem region modified to comprise a sequence encoding the artificial siRNA molecule, consisting of a guide and a passenger strand;... Agent:

20150018540 - Oligomer-conjugate complexes and their use: Oligonucleotides, chemically-modified oligonucleotides, and oligonucleotide-conjugate compl in research, diagnostics, and/or therapeutics are described herein.... Agent: Isis Pharmaceuticals, Inc.

20150018541 - Stabilisation of radiopharmaceutical precursors: The present invention relates to a method for improving stability of non fluoridated sugar derivatives, and in particular glucose derivatives such as 1,3,4,6-tetra-O-acetyl-2-O-trifluoromethanesulfonyl-β-D-mannopyranose which are used as precursors for production of radiofluoridated sugar derivatives for use in in vivo imaging procedures such as positron emission tomography (PET). The method comprises... Agent: Ge Healthcare Limited

01/08/2015 > 11 patent applications in 10 patent subcategories.

20150011739 - Tandem facial amphiphiles: The invention provides tandem facial amphiphiles for biochemical manipulations and characterization of membrane proteins, such as intrinsic membrane proteins. Members of this new family display favorable behavior with several membrane proteins. These amphiphiles can form relatively small micelles, and small changes in amphiphile chemical structures can result in large changes... Agent: Wisconsin Alumni Research Foundation

20150011740 - Fluorine-containing water soluble platinum complexes for tumor treatment and process of preparing same: Disclosed are fluorine-containing highly water-soluble platinum complexes for tumor treatment and preparation method, said platinum complexes being shown as formula (I); The present fluorine-containing platinum complexes exhibiting superior cytotoxicity and efficacy compare to the clinical drug oxaliplatin, the design strategy of the present platinum complexes is to enhance the solubility... Agent: Juang Su Vanguard Pharmacy,

20150011741 - Foam adsorption: The present invention provides methods for the isolation of an amphipathic, hydrophobic or hydrophilic compound from a medium that is either hydrophilic or hydrophobic, respectively, said methods comprising allowing the formation and/or accumulation of foam comprising said compound at the medium-gas interface, applying said foam directly onto an adsorbent which... Agent: Technische Universitaet Dortmund

20150011742 - Electrochemical synthesis of chloro-chitosan: The present disclosure provides methods for producing chitosan derivatives and the derivatives formed by these methods. The processes of the present disclosure utilize electrochemical methods to functionalize and/or modify amine and/or hydroxyl groups present on chitosan, to form new derivatives. In embodiments, a chloro-chitosan derivative may be prepared. The altered... Agent:

20150011743 - Method to improve the stability and broaden the ph range of family g/11 xylanases: The present invention relates to protein engineering, and concerns especially family G/11 xylanases, and genes encoding said enzymes. In specific, the invention concerns Trichoderma reesei XYNII gene, which codes for endo-1,4-β-xylanase (EC The invention describes how site-directed mutagenesis can be used to improve the properties of an enzyme to... Agent: Danisco US Inc.

20150011744 - Modifications for antisense compounds: The invention pertains to modifications for antisense oligonucleotides, wherein the modifications are used to improve stability and provide protection from nuclease degradation. The modifications could also be incorporated into double-stranded nucleic acids, such as synthetic siRNAs and miRNAs.... Agent:

20150011745 - Nucleic acid molecule for inhibiting activity of rnai molecule: The purpose of the present invention is to develop and provide a nucleic acid molecule that can specifically and efficiently inhibit the activity of a target RNAi molecule and can be produced safely at a low cost. Provided is a nucleic acid molecule for inhibiting the activity of a target... Agent: Osaka City University

20150011746 - Protected linker compounds: The invention features protected linker compounds which comprise at one terminus a protected amino group and at another other terminus a phosphorous activating group, such as a phosphoramidite group. These protected linker compounds are introduced chemically at the 5′-end of oligonucleotides for the purpose of preparing 5′-amino modified oligonucleotides. After... Agent:

20150011747 - Methods for making biocompatible polymerizable acrylate products: Sugar-acrylic monomers are synthesized to have a carbohydrate moiety linked to an acrylate group. The sugar-acrylic monomers may be polymerized to form polymers, adhesives, hydrogels, and the like. The sugar-acrylic monomers and polymers may be used in tissue engineering, adhesives and sealers, wound healing, and the like.... Agent: Empire Technology Development LLC

20150011748 - Method for the manufacture of concentrated aqueous solutions of alkali metal salt of carboxymethyl fructan: A method is for the manufacture of aqueous solutions of alkali metal salt of carboxymethyl fructan. More specifically the method for the manufacture of aqueous solutions includes at least 20% by weight of alkali metal salt of carboxymethyl fructan having a degree of carboxymethyl substitution of at least 1.2.... Agent: Italmatch Chemicals Spa

20150011749 - Use of certain metal-accumulating plants for the performance of organic chemistry reactions: Metal-accumulating plants for preparing compositions including a metal catalyst derived from the plants. The composition is substantially devoid of organic matter. Also, carrying out chemical reactions with the compositions prepared from metal-accumulating plants.... Agent: Centre National De La Recherche Scientifique

01/01/2015 > 4 patent applications in 4 patent subcategories.

20150005484 - Method for saccharification of biomass: A method for saccharification of lignocellulosic biomass, the method comprising (1) a pretreatment step of impregnating lignocellulosic biomass with an aqueous alkali solution, subjecting the resultant mixture to solid-liquid separation to remove part of the aqueous alkali solution, and then performing heat treatment, and (2) a saccharification step of enzymatically... Agent:

20150005485 - Synthetic heparin pentasaccharides: Preparation and use of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides useful for the preparation of synthetic heparinoids.... Agent: Alchemia Limited

20150005486 - Method for producing water-soluble nonionic cellulose ether excellent in storage stability: Provided is a water-soluble nonionic cellulose ether excellent in storage stability. More specifically, provided is a method for producing a water-soluble nonionic cellulose ether including an etherification step of reacting an alkali cellulose with an etherifying agent to obtain a crude cellulose ether, a washing step of washing the crude... Agent:

20150005487 - Sorbent comprising on its surface a cationic or protonizable aliphatic residue for the purification of organic molecules: The present invention relates to a sorbent comprising a solid support material, the surface of which comprises a residue of a general formula (I), wherein the residue is attached via a covalent single bond to a functional group on the surface of either the bulk solid support material itself or... Agent: Instraction Gmbh

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