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Organic compounds -- part of the class 532-570 series May archived by USPTO category 05/12

20120136142 - Vaccine compositions for marburg virus: Methods and immunogenic compositions for generating an immune response against Marburg virus are provided. The immunogenic composition includes antigens obtained from a Marburg viral strain in combination with an oleanolic acid triterpene adjuvant.... Agent: Western Illinois University Research Foundation

20120136143 - Methods and kits for sense rna synthesis: Methods and kits are provided for performing multiple rounds of sense RNA synthesis. The sense RNA molecules can be used in various research and diagnostic applications, such as gene expression studies involving nucleic acid microarrays.... Agent: Genisphere, LLC

20120136145 - Compositions and methods for inhibiting expression of eg5 gene: The invention relates to a double-stranded ribonucleic acid (dsRNA) for inhibiting the expression of the Eg5 gene (Eg5 gene), comprising an antisense strand having a nucleotide sequence which is less that 30 nucleotides in length, generally 19-25 nucleotides in length, and which is substantially complementary to at least a part... Agent:

20120136144 - Sirna targeting catenin, beta-1 (ctnnb1): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Dharmacon, Inc.

20120136146 - Process for the production of microfibrillated cellulose and produced microfibrillated cellulose: A process for producing microfibrillated cellulose comprises providing a slurry comprising cellulosic fibers, treating the slurry with an enzyme, mechanically treating the slurry so that the fibers are disintegrated wherein the mechanical treatment and the treatment with the enzyme is performed simultaneously in a single treatment step. In this way... Agent: Stora Enso Oyj

20120136147 - Method of hydrolyzing an enzymatic substrate: The invention is directed to droplet actuator devices and assay methods. The method may include immobilization of the enzymatic substrate including forming an inclusion complex with the substrate within an aqueous environment in contact with an oil.... Agent:

20120130059 - Anthracycline derivative conjugates, process for their preparation and their use as antitumor compounds: The present invention relates to conjugates of therapeutically useful anthracyclines with carriers such as polyclonal and monoclonal antibodies, proteins or peptides of natural or synthetic origin; methods for their preparation, pharmaceutical composition containing them and use thereof in treating certain mammalian tumors.... Agent:

20120130060 - Modified antisense oligopeptides with anticancer properties and method of obtaining them: The application of this drug in connection with its ability to adapt to the body allows the elimination of a tumor's tolerance to the drug. This drug has a wide spectrum of activity and a low level of toxicity; it is accessible for industrial production and effective at any stage... Agent:

20120130061 - Modified antisense oligopeptides with anticancer properties and method of obtaining them: The present invention relates to a method for the isolation and purification of nucleic acids by elution of nucleic acids from nucleic acid-containing samples and biological materials. The present invention further relates to a kit for carrying out the method of the invention.... Agent: Qiagen Gmbh

20120130062 - Enzymatic synthesis of carba-nad: The disclosure concerns the enzymatic synthesis of stable analogues of nicotinamide adenine dinucleotide NAD/NADH and nicotinamide adenine dinucleotide phosphate NADP/NADPH, the so-called “carba-NADs”, i.e. analogues of NAD/NADH or NADP/NADPH, respectively, comprising a carbacyclic sugar instead of ribose.... Agent: Roche Diagnostics Operations, Inc.

20120130063 - Method of producing a purified hyaluronic acid type: Provided a method of producing a purified hyaluronic acid type which comprises adding a water-soluble organic medium to a solution which comprises a hyaluronic acid type having an average molecular weight of 400 to 100,000 and has a pH of 3 or less to obtain a suspension, and adjusting a... Agent: Kewpie Corporation

20120130064 - Method for the hydrophilic processing of cellulose fibre and production method for hydrophilic cellulose fibre: This invention provides a method for hydrophilic treatment of cellulose fibers that can prevent coloring or decrease in fiber strength. The hydrophilic treatment method comprises a first oxidation step of oxidizing cellulose fibers in a first reaction solution containing an N-oxyl compound and a re-oxidizing agent for the N-oxyl compound;... Agent: The University Of Tokyo

20120130065 - Guar process monitoring methods: Disclosed are methods relating to monitoring the processing of polysaccharides and, in particular, monitoring the processing of guar in order to improve guar yield and/or lower impurity concentration in the wash effluent fluid.... Agent: Rhodia Operations

20120130066 - Method for precipitating a solute from a solution: A solute is precipitated from a solution of a solute, a solvent and a non-solvent by preparing the solutions and introducing the solution into a precipitation chamber contain a supercritical fluid.... Agent: The Hong Kong Polytechnic University

20120123102 - Modified pectins, compositions and methods related thereto: The present invention provides compositions of modified pectin and methods for preparing and using them.... Agent: La Jolla Pharmaceutical Company

20120123103 - Polyglyceryl compounds and compositions: Provided are compositions comprising one or more compounds having a structure comprising a node structure with from four to twelve carbon atoms, one or more (poly)glyceryl groups, and one or more hydrophobic moieties, wherein each of the one or more (poly)glyceryl groups is linked to the node structure by a... Agent:

20120123104 - Polyglyceryl compounds and compositions: Provided are compositions comprising one or more compounds having a structure comprising a node structure with from four to twelve carbon atoms, one or more (poly)glyceryl groups, and one or more hydrophobic moieties, wherein each of the one or more (poly)glyceryl groups is linked to the node structure by a... Agent:

20120123105 - Gene signature for diagnosis and prognosis of breast cancer and ovarian cancer: A first embodiment is a breast cancer prognosticator comprising a detection mechanism consisting a 15-gene signature. In addition there are embodiments comprised of 23-gene signatures and 28-gene signatures. The 28-gene signature may also be used for the prognosis of ovarian cancer. Another embodiment is a method to determine relapse free... Agent:

20120123106 - Method for isolating high-purity rna by means of paramagnetic microparticles and nanoparticles: The invention relates to a purification method for high-purity, DNA-free RNA using a mixture of nanocarrier beads and paramagnetic beads.... Agent: Stratec Molecular Gmbh

20120123107 - Nucleic acid cleavage complex and method for using the same: A nucleic acid cleavage complex is disclosed, which includes: a nanoparticle, a nucleic acid cleavage reagent, and a polynucleotide chain specifically recognizing a sequence of a target nucleic acid and having a first terminal and a second terminal opposite to the first terminal, wherein the first terminal is connected to... Agent: National Cheng Kung University

20120123108 - Bcl gene primers for detection and fingerprinting of bacillus anthracis: n

20120123109 - Luminescence quenching compounds: The quenching compounds of the invention are weakly luminescent cyanines that are substituted by one or more heteroaromatic quenching moieties. The quenching compounds of the invention exhibit little or no observable luminescence and efficiently quench a broad spectrum of luminescent compounds. The chemically reactive quenching compounds possess utility for labeling... Agent: Anaspec Incorporated

20120123110 - Plasmid dna extraction process: A process for the extraction of pDNA from cells is provided. In one aspect, the process comprises heating a liquid comprising the cells to an average temperature of from 95° C. to about 120° C. for a time of less than 10 seconds. In certain preferred aspects, the pDNA is... Agent:

20120123111 - Nª -hydroxy-l-arginine derivatives for the treatment of diseases: The present invention relates to physically-chemically and pharmacokinetically enhanced Nω-hydroxy-L-arginine (NOHA) derivatives and a method for producing the NOHA derivatives having enhanced physical-chemical and pharmacokinetic properties according to the invention.... Agent: Christian-albrechts-universitaet Zu Kiel

20120123112 - Regioselectively substituted cellulose esters produced in a halogenated ionic liquid process and products produced therefrom: This invention relates to novel compositions comprising regioselectively substituted cellulose esters. One aspect of the invention relates to processes for preparing regioselectively substituted cellulose esters from cellulose dissolved in ionic liquids. Another aspect of the invention relates to the utility of regioselectively substituted cellulose esters in applications such as protective... Agent: Eastman Chemical Company

20120116065 - Novel method for the synthesis of a trisaccharide: The present invention relates to an improved synthesis of a trisaccharide of the formula, novel intermediates used in the synthesis and the preparation of the intermediates.... Agent: Glycom A/s

20120116066 - Efficient and scalable process for the manufacture of fondaparinux sodium: The present invention relates to a process for the synthesis of the Factor Xa anticoagulent Fondaparinux and related compounds. The invention relates, in addition, to efficient and scalable processes for the synthesis of various intermediates useful in the synthesis of Fondaparinux and related compounds.... Agent: Reliable Biopharmaceutical Corporation

20120116067 - Method for the solid phase-based production of phosphate-bridged nucleoside conjugates: The invention relates to a method for producing phosphate-bridged nucleoside conjugates. In the method, a cyclosaligenyl nucleotide is produced first, to which a linker is added, which is used to perform the immobilization on a solid phase. A subsequent reaction with corresponding nucleophiles results in the desired phosphate-bridged nucleoside conjugates,... Agent: Universitaet Hamburg

20120116068 - Method for breaking down cellulose in solution: The present invention describes a process for the degradation of cellulose by dissolving the cellulose in an ionic liquid and treating it with an acid, if appropriate with addition of water.... Agent: Basf Se

20120108800 - Method for synthesizing nucleic acid: P

20120108801 - Disubstituted-aminodifluorosulfinium salts, process for preparing same and method of use as deoxofluorination reagents: The invention relates to disubstituted-aminodifluorosulfinium salts represented by the formula (I). Processes for preparing same and methods of use as deoxofluorinating reagent is also provided.... Agent: Omegachem Inc

20120108802 - Production of defined monodisperse heparosan polymers and unnatural polymers with polysaccharide synthases: A methodology for polymer grafting by a polysaccharide synthase allows the creation of a variety of glycosaminoglycan oligosaccharides that have a natural, chimeric, hybrid and/or unnatural sugar structure and/or a targeted size (i.e., substantially monodisperse in size).... Agent:

20120108803 - Sirna conjugate and preparation method thereof: Provided are an siRNA-polymer conjugate, and a method for preparing the same, and more specifically, to a hybrid conjugate formed by covalently bonding siRNA and a polymeric compound for improving the in vivo stability of siRNA, and to a preparation method of the hybrid conjugate. The conjugate of the present... Agent: Bioneer Corporation

20120108804 - Compositions and methods for preparing short rna molecules and other nucleic acids: The invention provides methods of preparing nucleic acids, such as RNA molecules, of a defined size or range of sizes. The invention provides compositions, methods and kits for use in the production and preparation of small RNA molecules (including without limitation micro-RNA, siRNA, d-siRNA and e-siRNA) and other nucleic acids... Agent: Life Technologies Corporation

20120108805 - Cellulose-based resin composition, molded body and case for electric and electronic devices: A cellulose resin composition for melt molding, containing a cellulose derivative having two or more kinds of aliphatic oxy groups having different carbon numbers (—OR) (wherein R represents an aliphatic group which may be unsubstituted or substituted), wherein a difference in carbon number between the aliphatic oxy group having the... Agent: Fujifilm Corporation