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Organic compounds -- part of the class 532-570 series November recently filed with US Patent Office 11/11

20110288281 - Method for 2-sulfation of glycosides: Method for selective 2-sulfation of glycosides.... Agent: University Of Washington

20110288282 - Method of preparing deoxyribofuranose compounds: The invention relates to methods for making deoxyribofuranose compounds such as compound (2) which are useful intermediates in the preparation of pharmaceutical compounds such as 5-amino-3-(2′-O-acetyl-3′-deoxy-β-D-ribofuranosyl)-3H-thiazolo[4,5-d]pyrimidin-2-one and the like.... Agent: Anadys Pharmaceuticals, Inc.

20110288283 - Process for producing glycosaminoglycans: The invention provides a process for the production of a composition comprising a glycosaminoglycan, said process comprising subjecting a homogenate of glycosaminoglycan-containing animal material to chromatography using a chromatographic matrix in the form of a membrane adsorber.... Agent: Hepmarin As

20110288284 - Methods and compositions for isolating polynucleotides: Methods of isolating target double-stranded polynucleotides with internal single-stranded regions are provided. Compositions and kits comprising double-stranded polynucleotides with internal single-stranded regions are also provided... Agent: Swift Biosciences, Inc.

20110288285 - Novel reagent compounds and methods of making same: The present invention describes novel compounds and methods for capping reactive groups on support and during multistep synthesis. These new capping reagents are also useful for high quality synthesis on solid supports and surfaces used as microarrays, biosensors, or in general as biochips. The compounds are also useful for controlling... Agent:

20110288286 - Process for the enzymatic production of cyclic diguanosine monophosphate employing a diguanylate cyclase comprising a mutated rxxd motif: A process is disclosed for the production of cyclic di-guanosine monophosphate (c-di-GMP) without the use of protecting groups by means of an enzymatic synthesis. The process comprises the coupling of two guanosine triphosphate (GTP) molecules so as to form a c-di-GMP molecule. This is done under the influence of a... Agent:

20110288287 - Halogen substituted saccharide, method for producing same, reaction composition of same and device for producing same: The present invention provides: a method for synthesizing a halogen-substituted saccharide from a leaving group-substituted saccharide in a short-time and continuously; a reaction composition; and a device for synthesis of same, i.e., the method being for synthesizing a halogen-substituted saccharide from a leaving group-substituted saccharide by a halogen-substituted saccharide synthesis... Agent:

20110282042 - Obtainment of chitin from shrimp waste by means of microwave and/or autoclaving in combination with organic acids in a single stage: This invention relates to the development of a new method of production of chitin through employment of a microwave process under pressure and/or autoclave with organic acids. This new method eliminates salts and proteins in a single stage and reduces contamination levels. The chitin obtained has application in the areas... Agent: Coyotefoods Biopolymer And Biotechnology, S.r.l. Mi

20110282043 - Methods and compositions comprising nucleic acid polymerization enhancers: Embodiments of the invention are directed to compositions and methods that use non-extendable oligonucleotides to enhance or improve synthesis or amplification of nucleic acids.... Agent: Cenetron Diagnostics LLC

20110282044 - Process for synthesizing oligonucleotide phosphate derivatives: The present invention describes simple, efficient, and enzyme-free method of making oligonucleotide phosphate derivatives. This invention presents novel process using automated synthesizer for synthesizing oligonucleotide phosphate derivatives using a diaryl phosphonate as reagent.... Agent: Alnylam Pharmaceuticals

20110282045 - Process for preparing purine nucleosides: The present invention for the stereoselective preparation of 2-deoxy-β-D-adenine nucleosides wherein a blocked 2-deoxy-α-D-arabinofuranosyl halide is coupled with the salt of an adenine derivative.... Agent: Genzyme Corporation

20110282046 - Process for preparation of cis-nucleoside derivative: The present invention relates to a novel and stereoselective synthetic process for the preparation of optically active cis-nucleoside derivatives of compound of Formula (I), wherein R3 represents H, F, Cl, C1-16 alkyl.... Agent:

20110282047 - Cyclodextrin-based polymers for therapeutics delivery: Described herein is a cyclodextrin containing polymer conjugate.... Agent: Cerulean Pharma Inc.

20110282048 - Cross-linking involving a polymeric carbohydrate material: The present invention relates to a method of cross-linking a polymeric carbohydrate material with a second material by means of a soluble carbohydrate polymer and a crosslinking agent. The present invention furthermore relates to the resulting cross-linked material, to uses of the cross-linked material, as well as to a kit... Agent: Swe Tree Technologies Ab

20110282049 - Low molecular weight cellulose mixed esters and their use as low viscosity binders and modifiers in coating compositions: Cellulose mixed esters are disclosed having low molecular weights and low degrees of polymerization. These new cellulose mixed esters include cellulose acetate propionate and cellulose acetate butyrate. The esters exhibit solubility in a wide range of organic solvents with minimal viscosity increase, are compatible with a wide variety of resins,... Agent: Eastman Chemical Company

20110282050 - Method of preparing alkali cellulose or a cellulose derivative: The throughput of a reactor for producing alkali cellulose and/or a cellulose derivative can be increased by using a granulated cellulose-based material for the preparation of alkali cellulose and/or a cellulose derivative. Cellulose derivatives of essentially the same quality can be produced as in known processes wherein powdered cellulose-based material... Agent:

20110282051 - High viscosity diutan gums: The production of a diutan polysaccharide exhibiting increased viscosity properties as compared with previously produced polysaccharide of the same type of repeating units. Such an improved diutan polysaccharide is produced through the generation of a derivative of Sphingomonas sp. ATCC 53159 that harbors a multicopy broad-host-range plasmid into which genes... Agent: C P Kelco U.s., Inc.

20110275794 - 5-position modified pyrimidines and their use: The present disclosure relates to the field of nucleic acid chemistry, specifically to 5-position modified uridines as well as phosphoramidite and triphosphate derivatives thereof. The present disclosure also relates to methods of making and using the same.... Agent: Somalogic, Inc.

20110275793 - Chemical rna synthesis method: The invention relates to a method for the chemical synthesis of RNA, comprising the following steps: a) bonding to a solid support of a monomer having formula (II) in which—X1 is a dimethoxytrityl group,—X6 is H or an OAc group or OX3, in which X3 is a group having formula... Agent:

20110275795 - Beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and production method therefor: The present invention relates to a beta-glucan-based scaffold for biological tissue engineering using radiation fusion technology, and to a production method therefor. According to the production method of the present invention for beta-glucan-based scaffold, radiation fusion tissue engineering, a beta-glucan-aqueous solution is cast and is then irradiated in a crosslinking... Agent: Quegen Biotech Co., Ltd.

20110269948 - Method for identifying compounds for cancer therapy: The present invention relates to an in vitro method for identifying and evaluating compounds useful in the treatment of different types of cancer, especially lung, breast, colorectal and bladder cancer in an individual, for determining the stage or severity of said cancer in the individual, or for monitoring the effect... Agent: Consejo Superior De Investigaciones Cientificas

20110269949 - Methods and compositions to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma: The present invention provides a method of treating cancer by providing to a subject in need thereof an immunogenic composition comprising a nucleic acid construct encoding a polypeptide comprising CTL epitopes PSMA288-297 and PRAME425-433, or a cross-reactive analogue. In embodiments of the present invention there is provided methods and compositions... Agent: Mannkind Corporation

20110269950 - Pharmaceutical composition containing a stabilised mrna optimised for translation in its coding regions: The present invention relates to a pharmaceutical composition comprising a modified mRNA that is stabilized by sequence modifications and optimised for translation. The pharmaceutical composition according to the invention is particularly well suited for use as an inoculating agent, as well as a therapeutic agent for tissue regeneration. In addition,... Agent: Curevac Gmbh

20110269951 - Sirna targeting cyclin-dependent kinase inhibitor 1b (p27, kip1) (cdkn1b): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Dharmacon, Inc.