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Organic compounds -- part of the class 532-570 series August inventions list 08/11

20110207918 - Pure and substantially pure rebaudioside a: The invention provides a high throughput, high purity, high yield system and method of isolating and purifying rebaudioside A (“Reb A”), with acceptable water solubility for all commercial uses, from commercially available Stevia rebaudiana starting material. The invention also provides a means of maximizing yields of 99+% purity Reb A... Agent: Sgf Holdings, LLC

20110207919 - Evaluating heparin preparations: Methods of evaluating heparin preparations, e.g., for suitability for use as a drug or for use in making a drug, by determining the absence, presence or amount of a structural signature that is indicative of the methods used to make the heparin preparation.... Agent: Momenta Pharmaceuticals, Inc.

20110207920 - 5-bromo-2'-deoxy-uridine labeled nucleotide triphosphates and nucleic acid probes and methods of making and using the same: 5-bromo-2′-deoxy-uridine (BrdU) labeled nucleotide triphosphates and nucleic acid probes are described herein. The BrdU labeled nucleotide triphosphates include a linker between the nucleotide triphosphate and the BrdU moiety. The linker can be cleavable or non-cleavable. The nucleotide triphosphates can be a ribonucleotide triphosphates, 2′-deoxyribonucleotide triphosphates or 2′,3′-dideoxyribonucleotide triphosphates. The nucleic... Agent: Life Technologies Corporation

20110207921 - Sulfated derivative of gastrodia elata polysaccharide, preparation method and antitumor use thereof: the sulfated position is mainly at 6-hydroxy of the gastrodia elata polysaccharide, with mean molecular weight of 6.5×104 and a specific rotation of +150.0° in a 0.5 mg/mL aqueous solution thereof. In vivo and in vitro experiments indicate that the sulfated derivative of gastrodia elata polysaccharide can inhibit the tumor... Agent: Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences

20110207922 - Monosaccharide preparation method: e

20110207923 - Isomerization of sugars: Disclosed are processes for isomerizing saccharides. Also disclosed are processes for converting saccharides to furan derivatives. Also disclosed are processes for converting starch to furan derivatives.... Agent: California Institute Of Technology

20110201793 - Process for production of glucopyranosyloxypyrazole derivative: P

20110201794 - Disaccharides for drug discovery: Methods are described for the preparation of combinatorial libraries of potentially biologically active disaccharide compounds. These compounds are variously functionalized, with a view to varying lipid solubility size, function an other properties, with the particular aim of discovering novel drug or drug-like compounds, or compounds with useful properties. The invention... Agent: Alchemia Limited

20110201795 - Methods of producing c-aryl glucoside sglt2 inhibitors: Method for the production of C-aryl glucoside SGLT2 inhibitors useful for the treatment of diabetes and related diseases. and intermediates thereof. The C-aryl glucosides may be complexed with amino acid complex forming reagents.... Agent: Bristol-myers Squibb Company

20110201796 - Dna sequence in plant caragana jubata with freeze tolerance: An isolated DNA sequence set forth in SEQ ID NO: 32, which is differentially expressed in apical buds of plant Caragana jubata (Pall.) under freezing conditions, is disclosed.... Agent: Council Of Scientific & Industrial Research

20110201797 - Nucleic acid shearing device with disposable cartridge: Apparatus, devices, and methods for shearing nucleic acids are provided. In one exemplary embodiment the device is a disposable nucleic acid shearing cartridge. The cartridge includes two reservoirs, an orifice structure disposed therebetween, and a fluid driver. The reservoirs are in fluid communication with each other by way of the... Agent: Massachusetts Institute Of Technology

20110201798 - Therapeutic compositions: This application relates to therapeutic siRNA agents and methods of making and using the agents.... Agent: Alnylam Pharmaceuticals

20110201799 - Synthesis of oligonucleotides: A method for preparing an oligonucleotide comprising the steps of a) providing a hydroxyl containing compound having formula (1), wherein B is a heterocyclic base, and radicals R2, R3 and R5 are as defined in the description; b) reacting said compound with a phosphitylating agent in the presence of an... Agent: Girindus Ag

20110201800 - Azacitidine process and polymorphs: Processes for preparing azacitidine. Further included are processes for the preparation of crystalline azacitidine crystalline Form (I) and mixtures of azacitidine crystalline Forms (I) and (II).... Agent: Dr. Reddy's Laboratories, Inc.

20110201801 - Saccharide structures and methods of making and using such structures: Described are oligosaccharides having a protecting group at two, a plurality, a majority of, or each position in the oligosaccharide which is amenable to derivatization. Collections, libraries and methods of making and using such oligosaccharides are also described.... Agent: Momenta Pharamaceuticals, Inc.

20110196138 - Separation of glycyrrhizic acid from licorice extract by ultrafiltration: A process for separating glycyrrhizic acid from licorice extract feed includes the steps of: providing a licorice extract feed and passing the licorice extract feed through an ultrafiltration device to produce a concentrate and a permeate. The ultrafiltration device contains a membrane that is selected to separate the glycyrrhizic acid... Agent: Mafco Worldwide Corporation

20110196139 - Preparation method for cellulose phosphite compounds: p

20110196140 - Chitosan having tropomyosin content assessed by method of determining tropomyosin in chitosan: This invention provides a method capable of easily determining with high accuracy a protein in chitosan, said protein having a potential relevance to the development of an allergy, specifically tropomyosin and the content of the peptide. According to the method, tropomyosin is determined by immunoassay with the chitosan being in... Agent:

20110196142 - Dna molecule for expressing hairpin rna, the constructing method and the use thereof: DNA molecule for expressing hairpin RNA, the constructing method and the use thereof are provided. The DNA molecule is a closed single-strand cyclic DNA molecule which is constructed by linking four fragments A, B, C and D as following order: A-C-B-D or A-D-B-C, wherein A is a sense strand or... Agent: Biotechnology Research Institute The Chinese Academy Of Agricultural Sciences

20110196141 - Locked and unlocked 2'-o phosphoramidite nucleosides, process of preparation thereof and oligomers comprising the nucleosides: The present invention relates to 2′-O-phosphoramidite of locked nucleoside and unlocked nucleoside, their synthesis and 2′-5′-linked oligomers oligomers comprising the nucleosides to delineate the structural requirements of 2′-5′ RNA/DNA: 3′-5′ RNA duplexes and also for use in antisense applications.... Agent: Council Of Scientific & Industrial Research

20110196143 - Dna encoding a plant lipase, transgenic plants and a method for controlling senescence in plants: Regulation of expression of senescence in plants is achieved by integration of a gene or gene fragment encoding senescence-induced lipase into the plant genome in antisense orientation. The carnation and Arabidopsis genes encoding senescence-induced lipase are identified and the nucleotide sequences are used to modify senescence in transgenic plants.... Agent:

20110196145 - Process for desilylation of oligonucleotides: The present invention relates to processes and reagents for oligonucleotide synthesis and purification. One aspect of the present invention relates to compounds useful for activating phosphoramidites in oligonucleotide synthesis. Another aspect of the present invention relates to a method of preparing oligonucleotides via the phosphoramidite method using an activator of... Agent: Alnylam Pharmaceuticals, Inc.

20110196144 - Synthesis and use of 2'-substituted-n6-modified nucleosides: An improved method of preparing a sugar modified nucleoside analog includes a protocol in which a hydroxy group of a sugar is selectively deprotected and oxidized prior to nucleophilic modification of the corresponding carbonyl group. The modified sugar is then coupled to a heterocyclic base that is modified with a... Agent: Valeant Pharmaceuticals North America

20110196146 - Methods, compositions, and kits for recovery of nucleic acids or proteins from fixed tissue samples: Methods and materials for improving nucleic acid or protein recovery from samples preserved in liquid cytological preservative solutions by utilizing scavenging agents, such as hydrazine- and hydrazide-containing compounds, are provided. Lysis solutions comprising hydrazine- and hydrazide-containing compounds and kits comprising the same are also provided.... Agent: Qiagen Gaithersburg Inc.

20110190481 - Extraction method for sialic acid-containing compound from plant: An object of the present invention is to provide an inexpensive and simple extraction method for a sialic acid-containing compound from a raw material which is easily available and has no risk of contamination with pathogens affecting animals (raw material which has high safety) without requiring the use of a... Agent: Inc Admin Agcy Natl Agric & Food Res. Organization

20110190482 - Polymer encapsulated aluminum particulates: The present invention relates to use of novel bioinformatics approach for predicting and identifying Scaffold/Matrix attachment regions (S/MARs) from different genomic database.... Agent: Avesthagen Limited

20110190483 - Stimulus-responsive apta chelamers: Disclosed are apta-chelamers comprising aptamer domains tethered to rationally designed synthetic protein-binding modules, and methods of designing and making the same. Also disclosed are stimulus-responsive apta-chelamers capable of simultaneously or sequentially binding (and, thus, inhibiting) two protein targets.... Agent: The Administrators Of The Tulane Educational Fund

20110190484 - Nucleic acid molecule: The invention relates to an isolated nucleic acid molecule encoding a polypeptide capable of producing a triterpenoid hydrocarbon. The invention also relates to the encoded polypeptide, a vector comprising the nucleic acid molecule, a recombinant non-human organism comprising the nucleic acid molecule, and to methods of producing a triterpenoid hydrocarbon... Agent: Wwcc Limited

20110190485 - Solid-supported ether disulfides: e

20110190486 - Sulfonamide derivatives of polycyclic dyes used for analytical applications: The invention concerns the production of quinoline compounds containing sulfonic acid groups, the said quinoline compounds and their conversion into dyes containing sulfonic acid groups. The dyes according to the invention are used especially to label analytes, for example to label biomolecules.... Agent: Atto-tec Gmbh

20110190487 - Method for crosslinking beta-cyclodextrin for cholesterol trapping and regeneration thereof: Disclosed herein is the use of crosslinked beta-cyclodextrin as a trap for removing cholesterol. The crosslinked beta-cyclodextrin is prepared by crosslinking beta-cyclodextrin in the presence of a crosslinking agent. Treatment with the crosslinked beta-cyclodextrin results in cholesterol-depleted foods. After application to foods, the crosslinked beta-cyclodextrin which traps cholesterol therein can... Agent: