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Organic compounds -- part of the class 532-570 series May archived by USPTO category 05/11

20110124850 - Glycorandomization and production of novel vancomycin analogs: The present invention provides glycorandomized structures and combinatorial methods for rapidly generating a diverse library of glycorandomized structures, comprising incubating one or more aglycons and a pool of NDP-sugars in the presence of a glycosyltransferase. The glycosyltransferase may be one that is associated with or involved in production of natural... Agent:

20110124851 - Method of isolation of nucleic acids: A method of isolation of nucleic acids from a biological sample of cells comprising a combination of a solid phase cell nuclei isolation procedure with a solid phase nucleic acid isolation method.... Agent: Omega Bio-tek, Inc.

20110124852 - Molecular markers for identification of fat and lean phenotypes in chickens: The invention provides molecular methods of screening chickens to determine those more likely to have a lean or fat phenotype by identifying the presence of at least one polymorphism in genetic material of a chicken in the thyroid hormone repressible gene (THRG) or its 3′ untranslated region (SEQ ID NO:... Agent: University Of Delaware

20110124853 - Conjugates and compositions for cellular delivery: This invention features conjugates, degradable linkers, compositions, methods of synthesis, and applications thereof, including cholesterol, folate, galactose, galactosamine, N-acetyl galactosamine, PEG, phospholipid, peptide and human serum albumin (HSA) derived conjugates of biologically active compounds, including antibodies, antivirals, chemotherapeutics, peptides, proteins, hormones, nucleosides, nucleotides, non-nucleosides, and nucleic acids including enzymatic nucleic... Agent:

20110124854 - Cosmetic composition containing one or more compounds of the beta-(1,3)-glucuronan or beta-(1,3)-glucoglucuronan type: The invention relates to a cosmetic composition that contains one or more compounds of the β-(1,3)-glucuronane or β-(1,3)-glucoglucuronane type as well as the pharmaceutically acceptable salt thereof, and to the use of this composition and these compounds for various cosmetic applications.... Agent:

20110118454 - Method for preparing nucleotides and related analogues by synthesis on soluble substrate, and biological tools thus prepared: The invention concerns a method for preparing monomer nucleotides or nucleotide analogues comprising the steps of: (1) coupling a soluble polyethylene glycol support provided with at least one diacid or ether-acid linker and a monomer nucleoside or nucleoside analogue to an amine group or hydroxyl group of the nucleoside with... Agent:

20110118455 - Protecting group for indole group, nucleic acid-synthesizing amidite and nucleic acid-synthesizing method: e

20110118456 - Interfering rna molecules: The present invention is related to a ribonucleic acid comprising a double stranded structure whereby the double-stranded structure comprises a first strand and a second strand, whereby the first strand comprises a first stretch of contiguous nucleotides and whereby said first stretch is at least partially complementary to a target... Agent: Silence Therapeutics Ag

20110118457 - Method for nucleic acids isolation: The present invention provides a method for isolating nucleic acids. The method comprises: contacting a sample containing nucleic acids with a solid phase in a first aqueous solution to provide a loaded solid phase; washing the loaded solid phase with a second aqueous solution to provide a washed solid phase;... Agent:

20110118458 - Use of mediators in the production of fiberboards: The invention relates to a novel mediator used in the production of wood composite materials that are devoid of binding agents.... Agent:

20110112282 - Ido inhibitors and therapeutic uses thereof: Compounds of formula (I), and pharmaceutically acceptable salts thereof, in which each compound is adapted to occupy the binding site of human IDO, which comprises a large hydrophobic pocket A and a second, proximal hydrophobic pocket B, the compound comprising at least one of the following elements: (i) a large... Agent:

20110112284 - Methods for modulating ikkalpha activity: A method for modulating NF-κB dependent gene transcription in a cell comprised of modulating IKKα protein activity in the cell. The present invention also provides siRNA compositions and methods thereof for modulating NF-κB dependent gene transcription.... Agent: Boehringer Ingelheim International Gmbh

20110112283 - Rna interference mediating small rna molecules: Double-stranded RNA (dsRNA) induces sequence-specific post-transcriptional gene silencing in many organisms by a process known as RNA interference (RNAi). Using a Drosophila in vitro system, we demonstrate that 19-23 nt short RNA fragments are the sequence-specific mediators of RNAi. The short interfering RNAs (siRNAs) are generated by an RNase III-like... Agent: Max-planck-gesellschaft Zur Foerderung Der Wissenschaften E.v.

20110112285 - Novel method for preparing oligonucleotides comprising a 5-phosphate monoester or 5-thiophosphate monoester end: The preparation of oligonucleotides having a 5′-phosphate monoester end.... Agent: Universite Joseph Fourier

20110112286 - Method for dissolving cellulose and a cellulosic product obtained from a solution comprising dissolved cellulose: The present invention relates to a method for dissolving cellulose. The method comprises—introducing cellulosic raw material,—treating the cellulosic raw material in an enzymatic treatment process,—mixing the cellulosic raw material after the enzymatic treatment in an aqueous solution in order to obtain an aqueous intermediate product containing the cellulosic raw material... Agent: Tty Saatio

20110105738 - Diaryl hepatonoid-based compounds useful as virus inhibitors: The present invention relates to the use of diaryl hepatonoid-based compounds of formula (1) for inhibiting viral activity. The diaryl hepatonoid-based compounds have an excellent effect of inhibiting viral activity, and thus will be useful as therapeutic agents against virus-related diseases.... Agent:

20110105739 - Novel matrix materials, methods for the production thereof, and use thereof in methods for isolating biomolecules: The invention relates to functionalized matrix materials or matrices that have structures of general formula (I) T-(C═O)O—B-D, methods for the production thereof, and the use thereof in methods for purifying and isolating biomolecules.... Agent:

20110105740 - Soluble tnf receptors and their use in treatment of disease: The present invention relates to tumor necrosis factor (TNF) antagonists and corresponding nucleic acids derived from tumor necrosis factor receptors (TNFRs) and their use in the treatment of inflammatory diseases. These proteins are soluble secreted decoy receptors that bind to TNF and prevent TNF from signaling to cells. In particular,... Agent: Ercole Biotech, Inc., A Delaware Corporation

20110105741 - Nucleic acids encoding a g-protein coupled receptor involved in sensory transduction: The invention provides isolated nucleic acid and amino acid sequences of sensory cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sensory cell specific G-protein coupled receptors.... Agent: The Regents Of The University Of California

20110105742 - Optimized dna sequence of an antibody to improve quality and yield of bacterially expressed antibody fusion proteins: Object matter of the invention is an optimized DNA sequence encoding the scFv(FRP5) antibody fragment. This novel sequence prevents the generation of the undesired by-product in the context of an scFv(FRP5)-ETA fusion protein, and possibly also other bacterially expressed scFv(FRP5)-containing fusion proteins. The DNA sequence of the scFv(FRP5) domain of... Agent: Topotarget Germany Ag

20110105743 - Improved method and process for synthesis of 2',3'-didehydro-2',3'-dideoxynucleosides: A method is disclosed for synthesizing 2′,3′-didehydro-2′,3′-dideoxynucleosides (d4Ns) from a nucleophile-mediated elimination, such as a telluride-mediated elimination reaction. After substitution of 2,2′-anhydronucleosides with a nucleophile, such as a telluride monoanion, a telluride intermediate is formed, and its elimination leads to formation of the olefin products (d4Ns). This disclosure describes this... Agent:

20110105744 - Method for glycosylating and separating plant fiber material: The invention relates to a method for hydrolyzing a plant fiber material and producing and separating a saccharide including glucose. The method of the invention includes a hydrolysis process of using a cluster acid catalyst in a pseudo-molten state to hydrolyze cellulose contained in the plant fiber material and produce... Agent: