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Organic compounds -- part of the class 532-570 series January recently filed with US Patent Office 01/11

20110021765 - Fluorinated lanthanide probes for 19f magnetic resonance applications: The invention provides a paramagnetic lanthanide (III) complex comprising a lanthanide (III) ion and a polydentate ligand wherein the polydentate ligand comprises one or more fluorine atoms in which the distance of at least. one of the fluorine atoms to the lanthanide ion is less than 7, said polydentate ligand... Agent: Mannava & Kang, P.C.

20110021766 - Epimerized derivatives of k5 polysaccharide with a very high degree of sulfation: A new method is described for the oversulfation of epiK5-N-sulfate to obtain an epiK5-amine-O-oversulfate with very high sulfation degree which, by subsequent N-sulfation, provides new epiK5-N,O-oversulfate-derivatives with a sulfation degree of at least 4, basically free of activity on the coagulation parameters and useful in the cosmetic or pharmaceutical field.... Agent: Nixon & Vanderhye, PC

20110021767 - B12-dependent dehydratases with improved reaction kinetics: Sequences of B12-dependent dehydratases with improved reaction kinetics are presented. Use of these B12-dependent dehydratases reduce the rate of the enzyme's suicide inactivation in the presence of glycerol and 1,3-propanediol. The enzymes were created using error-prone PCR and oligonucleotide-directed mutagenesis to target the DhaB1 gene, which encodes the α-subunit of... Agent: E I Du Pont De Nemours And Company Legal Patent Records Center

20110021768 - B12-dependent dehydratases with improved reaction kinetics: Sequences of B12-dependent dehydratases with improved reaction kinetics are presented. Use of these B12-dependent dehydratases reduce the rate of the enzyme's suicide inactivation in the presence of glycerol and 1,3-propanediol. The enzymes were created using error-prone PCR and oligonucleotide-directed mutagenesis to target the DhaB1 gene, which encodes the α-subunit of... Agent: E I Du Pont De Nemours And Company Legal Patent Records Center

20110021769 - Process for producing fluorocytidine derivatives: wherein each of R1 and R2 independently represents a hydroxyl protecting group, with an acylating agent of formula (III): X—C(═O)—R3, wherein X is an acyl activating group in an organic solvent to produce an acylated compound; (b) deprotecting the acylated compound to obtain the compound of formula (I); and (c)... Agent: Cohen, Pontani, Lieberman & Pavane LLP

20110021770 - Fungus polyose composition with immunity enhancing effect and application thereof: The present invention relates to a compound fungus polyose with the effect of enhancing immunity. The compound is prepared with raw material as follows: Lentinus edodes 8˜100, Poria cocos 15˜100, Dictyophora indusiata 10˜200, Tremella fuciformis 15˜80, Paecilomyces hepiali mycelium 2˜50. The present invention also relates to the use of compound... Agent: Wang & Ho

20110015379 - Method and kit for preparation of sample for use in nucleic acid amplification: The object is to remove substances that can inhibit nucleic acid amplification from biological samples and nucleic acid extracts, and to allow convenient and accurate evaluation of the presence or absence of a target nucleic acid or the expression level of a target gene in a biological sample, by nucleic... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, L.L.P.

20110015380 - Systems, compositions and methods for nucleic acid detection: The invention relates to stretch measurements of nucleic acids and correlating those measurements to the extent of double- and single-stranded content of a nucleic acid of interest, and to compositions, systems, and devices related thereto. In preferred embodiments, one performs the stretch or elasticity measurements under conditions such that one... Agent: Peter G. Carroll Medlen & Carroll, LLP

20110015381 - Instrument and method for collecting nucleic acids: An instrument and a method for conveniently collecting nucleic acids from a biological nucleic acid-containing sample are provided. A nucleic acid-capturing tip having silica-containing solid phases enclosed therein in such a state as being capable of coming into contact with a liquid, wherein the solid phases have a water-flowing regions... Agent: Dickstein Shapiro LLP

20110015383 - Derivatives of nucleoside-5'-o-hypophosphates and their mono- and dithiohypophosphate analogues and the process for the manufacture thereof: The subject of the invention includes derivatives of nucleoside-5′-O-hypophosphates and their mono- and dithiohypophosphate analogues, in particular 5′-O-[β,β-dialkyl-(α-thiohypophosphate)]-, 5′-O-[β,β-dialkyl-(α,α-dithiohypophosphate)]-, 5′-O-[β,α-dialkyl-(α,β-dithiohypophosphate)-, 5′-O-[β-alkyl-(α-thiohypophosphate)]-, 5′-O-[β-alkyl-(α, oc-dithiohypophosphate)]-, 5′-O-(a-thiohypophosphate)]- and 5′-O-(a,a-dithiohypophosphate)nucleosides.... Agent: Brooks Kushman P.C.

20110015382 - Synthesis of n-fmoc protected deoxy nucleosides, ribo nucleosides, modified deoxy and ribo nucleosides, and phosphoramidites, and their use in oligonucleotide synthesis: This invention relates to synthesis of novel -N-FMOC protected nucleosides, succinates, phosphoramidites, corresponding solid supports that are suitable for oligo deoxy nucleosides and RNA oligonucleotide synthesis. Our discovery using N-FMOC as nucleoside base protecting group, which is highly base labile protecting group is a novel approach to obtain highest purity... Agent: Indu M. Anand, Esq.

20110015384 - Sulfurization agent and its use: The use of a sulfurizing agent of formula A: or a salt, hydrate, solvate, or a mixture thereof, in which all R groups, independently, represent H or an organic group, in sulfurization. The sulfurizing agent is preferably a formamidine disulfide. It is found a particularly suitable alternative to existing sulfurizing... Agent: Young & Thompson

20110015385 - Acylation of carbohydrates: e

20110015386 - Permethylation of oligosaccharides: A solid-phase permethylation procedure is described. For example, solid-phase permethylation can be utilized to prepare permethylated linear and branched, neutral and sialylated oligosaccharides, which can be analyzed by MALDI-MS.... Agent: Barnes & Thornburg LLP

20110015387 - Method for the depolymerization of cellulose: A process for the depolymerization of cellulose, in which a solution of cellulose in an ionic liquid is brought into contact with a solid acid as catalyst, is claimed. The cellulose can be depolymerized within a short reaction time to form a low molecular weight or oligomeric reaction mixture having... Agent: Briscoe, Kurt G. Norris Mclaughlin & Marcus, Pa

20110009607 - Method for preparing dna fragment having sticky end: The present invention provides a method for preparing a DNA fragment, in which a desired double-stranded DNA fragment having a sticky end is directly and easily obtained from an amplification product (an amplified fragment) after PCR without a restriction enzyme digestion. The method for preparing a DNA fragment having a... Agent: Birch Stewart Kolasch & Birch

20110009606 - Synthesis of 2',3' - and 3',5' -cyclic phosphate mono-and oligonucleotides: The invention provides a novel method of 2′,3′-cyclic phosphate and phosphorothioate of mono and oligonucleotide synthesis. The invention also provides a novel method of the synthesis of 3′,5′-cyclic phosphate and phosphorothioate mononucleotide. The invention also envisions providing kits comprising at least one composition disclosed in the present invention.... Agent: Indu M. Anand, Esq.

20110009608 - Automatic refining apparatus, multi-well plate kit and method for extracting hexane from biological samples: The present invention relates to an automatic refining apparatus for separating target materials from a plurality of biological sample solutions by using magnetic particles to which the magnetic particles are to be reversibly coupled, and to a multi-well plate kit for use in the automatic refining apparatus. Further, the present... Agent: Cantor Colburn LLP

20110009609 - 2'-hydroxy-protected ribonucleoside derivative and production method thereof: The present invention relates to a method for producing a 2′-hydroxy-protected nucleoside derivative by reacting a ribonucleoside with an acylating reagent in the presence of a metal complex consisting of a copper compound and an optically active ligand. By the method according to the present invention, a 2′-hydroxy-protected ribonucleoside derivative,... Agent: Wenderoth, Lind & Ponack, L.L.P.

20110009610 - Process for the acetylation of lignocelluloses, hemicelluloses, and celluloses with ketene: The invention relates to a process for acetylating celluloses, lignocelluloses and hemicelluloses such as wood, straw and cotton, and regenerated celluloses produced from natural products, by means of ketene.... Agent: Brooks Kushman P.C.

20110009612 - Automated solution-phase iterative synthesis: The first method for iterative solution-phase biomolecule synthesis is described. The method requires only 3 or fewer equivalents of building block at each coupling cycle, and incorporates a FSPE step at the end of each coupling/deprotection sequence to eliminate most byproducts.... Agent: Mckee, Voorhees & Sease, P.L.C

20110009611 - Clarification of sphingans and compositions thereof: The invention relates to mutant strains of the genus Sphingomonas which have a mutation in at least one gene encoding a protein involved in polyhydroxybutyrate (“PHB”) synthesis that allows the mutant strains to produce PHB-deficient sphingans. The invention is also directed to a process for preparing a clarified sphingan solution... Agent: Cp Kelco Us, Inc C/o Pete Pappas, Sutherland, Asbill & Brennan LLP

20110009613 - Method of processing beta-glucan: The invention relates to a method of degrading plant-based β-glucan into a controlled molecular size by hydrolyzing β-glucan in a closed space under pressure by means of an acid at an elevated temperature. The invention also relates to a degraded β-glucan product. The β-glucan product obtained is useful in foodstuffs... Agent: Birch Stewart Kolasch & Birch

20110009614 - Processes and reactor systems for converting sugars and sugar alcohols: Processes and reactor systems are provided for the conversion of sugars to sugar alcohols using a hydrogenation catalyst, which includes apparatus and method for in-line regeneration of the hydrogenation catalyst to remove carbonaceous deposits.... Agent: Quarles & Brady LLP

20110003980 - Oligo-aminosaccharide compound: An oligo-aminosaccharide compound formed by binding 3 to 6 saccharides, such as 2,6-diamino-2,6-dideoxy-α-(1→4)-D-glucopyranose oligomers, or a salt thereof, which has high affinity to a double-stranded nucleic acid.... Agent: Greenblum & Bernstein, P.L.C

20110003981 - Process for producing radioactive fluorine labeled organic compound, and relevant synthetic apparatus and program: A method of producing a radioactive-fluorine-labeled compound has a step of heating in a reaction vessel a mixture containing [18F] fluoride ions, a phase transfer catalyst, potassium ions, and water to evaporate water from the mixture (S10), and in the above step has a step of measuring a temperature of... Agent: Osha Liang L.L.P.

20110003982 - Process for the preparation of purified beta-(1,3)-d-glucans: There is provided a process for the preparation of purified β-(1,3)-D-glucans, comprising the steps of providing an aqueous β-(1,3)-D-glucan initial solution having a pH of above 11.0, filtering the aqueous β-(1,3)-D-glucan initial solution to obtain a β-(1,3)-D-glucan containing filtrate, adjusting the pH of the β-(1,3)-D-glucan containing filtrate with an acid... Agent: Cargill, Incorporated

20110003983 - Method of obtaining conformational polymorph of sucrose: A new sucrose is obtained through the present invention. The new sucrose has a lower solubility and a lower melting point. Thus, the new sucrose has a higher stability. The new sucrose obtained through the present invention can be used as an added functionality excipient of drug in pharmaceutical industry.... Agent: Jackson Intellectual Property Group PLLC