Organic compounds -- part of the class 532-570 series inventions 09/09

20090240055 - Method for 1h-imidazo[4,5-c] pyridines and analogs thereof: Methods and intermediates for preparing compounds of the Formulas: (I and X) are disclosed. The methods include a method providing a compound of the Formula: (IV) and converting a compound of Formula IV to a compound of Formula I, a method providing a compound of the Formula: (VIII) and converting... Agent: Wolf Greenfield & Sacks, P.C.

20090240056 - Methods for making 4-tetrazolyl-4-phenylpiperidine compounds: where Ar1 is —C3-C8 cycloalkyl, phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Ar2 is phenyl, naphthyl, anthryl, phenanthryl or -(5-7-membered) heteroaryl, each being unsubstituted or substituted with one or more R2 groups; Z1 and Z2 are each independently a... Agent: Dechert LLP

20090240057 - 3,4-dihalogenoisothiazole derivative, and agricultural or horticultural plant disease-controlling agent: (wherein R1 is a halogen atom; A is an oxygen atom or a sulfur atom; and R is a C1-C6 alkyl group, a C2-C5 alkenyl group, a C2-C5 alkynyl group, a C3-C6 cycloalkyl group, a phenyl group or a 5- to 10-membered heterocyclic group containing at least one of oxygen... Agent: Bacon & Thomas, PLLC

20090240058 - Activator for peroxisome proliferator-activating receptor delta: in which each of R11 and R13 is a hydrogen atom, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, an alkyl group having 1 to 8 carbon atoms and a halogen atom substituent, etc.; R12 is a hydrogen atom, an... Agent: Jones Day

20090240059 - Monovalent and divalent salts of n-(5-hydroxynicotinoil) -l-glutamic acid exhibiting psychotropic (antidepressant and anxiolytic), neuroprotective, geroprotective and cerebroprotective action: The invention relates to medicine, in particular to mono- and divalent salts of N-(5-hydroxynicotinoil)-L-glutaminic acid exhibiting psychotropic antidepressant, anxiolytic, heroprotective, neuroprotective, antihypoxia cerebroprotective and nootropic action. The novel compounds differ from the known preparations, including the closest prior art in the form of a N-(5-hydroxynicotinoil)-L-glutaminic acid base (nooglucotyl), in that... Agent: Collard & Roe, P.C.

20090234121 - Tridentate (nnc) catalysts for the selective oxidation of hydrocarbons: The synthesis of discrete, air, protic, and thermally stable transition metal NNC complexes that catalyze the CH activation and functionalization of alkanes and arenes is disclosed. Methods for the selective conversion of methane to methanol or methyl esters in acidic and neutral media are disclosed.... Agent: Pillsbury Winthrop Shaw Pittman LLP

20090234122 - Cyanine dye and optical recording medium: The present invention has an object to widen the range of applicable field of organic compounds to be selected as light absorbing materials in various fields including information recordings, solar energy generations, electric machinery apparatuses, electric communicating apparatuses, optical apparatuses, clothes, building/bedding/decorating products, sanitary and health goods, and agricultural materials,... Agent: Browdy And Neimark, P.l.l.c. 624 Ninth Street, Nw

20090234123 - Processes for the preparation of clopidogrel hydrogen sulfate polymorphic form i: Processes for the preparation of clopidogrel hydrogen sulfate of polymorphic form I are described which include use of specific solvents and process measures to avoid formation of undesired by-products.... Agent: Swanson & Bratschun, L.L.C.

20090234124 - Polyetheramine production method: The present invention relates to a process for the preparation of 3,7-diazabicyclo[3.3.1]nonane compounds. According to the invention, in a first step, a dicarboxylic acid ester is reacted with a pyridine aldehyde and a primary amine. The piperidone which forms is reacted in a second stage with formaldehyde and a further... Agent: Clariant Corporation Intellectual Property Department

20090234125 - Amorphous retapamulin and processes for preparation thereof: An amorphous form of Retapamulin, preferably in powder form, and processes for preparation thereof, are provided. Amorphous Retapamulin of the present invention can contain less than about 10 percent crystallinity, preferably less than about 5 percent crystallinity. Pharmaceutical compositions comprising amorphous Retapamulin are also provided.... Agent: Kenyon & Kenyon LLP

20090234126 - Process for the synthesis of arylamines from the reaction of an aromatic compound with ammonia or a metal amide: A catalytic process for the synthesis of aromatic primary amines, reagent compositions for effecting the process, and transition metal complexes useful in the process, are provided.... Agent: Drinker Biddle & Reath Attn: Intellectual Property Group

20090234127 - Process for the preparation of (3s)-3-amino-n-cyclopropyl-2-hydroxyalkanamide derivatives: The present invention relates to a process for the preparation of (2S,3S)-3-amino-N-cyclopropyl-2-hydroxyalkanamides, and their use in the preparation of HCV inhibitors and cathepsin inhibitors.... Agent: Townsend And Townsend And Crew, LLP

20090234128 - Process for the preparation of intermediates of rosiglitazone, rosiglitazone and new polymorphic forms thereof: The invention relates to a polymorphic form of 5-(4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzylidene)-2,4-thiazolidinedione (Formula (I)): to a process for its preparation and to the use of such compound for preparing rosiglitazone in the form of a free base or a salt thereof. The invention also relates to a polymorphic form of rosiglitazone in the... Agent: Frommer Lawrence & Haug

20090234129 - Synthesis of nicotine derivatives from nicotine: Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described.... Agent: Myers Bigel Sibley & Sajovec

20090227796 - Papaver somniferum strain with high concentration of thebaine: The present invention is directed to an improved poppy straw, concentrate of poppy straw and opium of Papaver somniferum for the production of thebaine containing little or no oripavine, codeine or morphine. The present invention also provides plants, stands and seeds of Papaver somniferum and methods for the production of... Agent: Philip S. Johnson Johnson & Johnson

20090227797 - Modulators of atp-binding cassette transporters: The present invention relates to modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator, compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.... Agent: Vertex Pharmaceuticals Inc.

20090227798 - Novel processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol: The present invention provides various processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol. These processes may be characterized by the following scheme:... Agent: Andrea Q. Ryan Sanofi-aventis U.s. LLC

20090227799 - Novel antimalarial agent containing heterocyclic compound: e

20090227800 - novel process for the preparation of lercanidipine: The invention provides a novel process for the preparation of lercanidipine or a pharmaceutical acceptable salt using novel intermediates. Thus, 2,N-dimethyl-N-(3,3-diphenylpropyl)-1-amino-2-propanol is reacted with trimethylsilyl chloride in presence of triethyl amine in methylene chloride to give 2,N-dimethyl-2-(trimethylsilyloxy)-N-(3,3-diphenylpropyl)-1-propanamine, which is then reacted with 2,6-dimethyl-5-methoxycarbonyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carbonyl chloride for 2 hours and crystallized to... Agent: Caesar, Rivise, Bernstein, Cohen & Pokotilow, Ltd.

20090221825 - Process for the preparation of 3-hydroxymorphinan derivatives: Processes are described for the synthesis of 3-hydroxymorphinan derivatives by hydrolysis of side products from the O-demethylation of 3-methoxymorphinan derivatives.... Agent: Mallinckrodt Inc.

20090221826 - Process for making topotecan: A process of making topotecan or a pharmaceutically acceptable salt thereof comprising reacting an iminium salt with 10-hydroxy-camptothecin.... Agent: Cohen, Pontani, Lieberman & Pavane LLP

20090221827 - Processes for the preparation of different forms of (s)-(+)-clopidogrel besylate: Disclosed herein are the improved processes for the preparation of different forms of (S)-(+)-Clopidogrel besylate, pharmaceutical compositions containing them and their use in medicine.... Agent: Nixon & Vanderhye, PC

20090221828 - Process for preparing 1-halo-2,7-naphthyridinyl derivatives: A process for preparing 1-halo-2,7-naphthyridinyl derivatives is described (I), wherein X is Cl or Br; which process comprises the following steps: (i) reaction of a 3-cyano-4-methylpyridine derivative of formula (A): with a compound of formula (II), in the presence of an N,N-dimethylformamide diC1-6alkylacetal; to give an enamine derivative of formula... Agent: Mcdonnell Boehnen Hulbert & Berghoff LLP

20090221829 - 3,4-dihydroisoquinolinium salt derivatives: The present invention relates to 3,4-dihydroisoquinolinium salt derivatives. More specifically, the present invention relates to 3,4-dihydroisoquinolinium salt derivatives of the following chemical formula (I).... Agent: The Nath Law Group

20090221830 - Fexofenadine polymorphs and processes of preparing the same: Anhydrous crystalline fexofenadine hydrochloride Form C, crystalline fexofenadine acetate monohydrate Form D, crystalline fexofenadine acetate dihydrate Form E and crystalline fexofenadine free base monohydrate Form F, processes of preparing the same, pharmaceutical compositions thereof, therapeutic uses thereof and methods of treatment therewith.... Agent: Conley Rose, P.C.

20090221831 - Method for producing n,n-bis(pyridin-2ylmethyl)-1,1-bis(pyridin-2-yl)-1-aminoalkane compounds and metal complex salts containing these compounds: h

20090221832 - Process for preparing ketones from alpha-oxo carboxylates and aryl bromides:

20090221833 - Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof: Processes for the purification of lercanidipine hydrochloride are provided which uses a binary system of an alcohol-containing solvent such as methanol and an aliphatic ester-containing solvent such as isopropyl acetate. Processes for the preparation of substantially amorphous lercanidipine hydrochloride are also provided. Also provided is lercanidipine hydrochloride substantially in polymorph... Agent: M. Carmen & Associates