Organic compounds -- part of the class 532-570 series inventions 07/09

20090192312 - Brain function-improving agent, and functional food containing the improving agent: There are provided a brain function improving agent having an effect of improving learning and memory abilities, and a functional food containing the function improving agent. A preparation comprising a pyrroloquinoline quinone or a salt thereof alone or in combination with coenzyme Q10 and a functional food containing the preparation... Agent: Fitch, Even, Tabin & Flannery

20090192313 - Process for producing 5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxylic acid: e

20090192314 - Process for the preparation of chiral 8-(3-aminopiperidin-1yl)-xanthines: The invention relates to an improved process for preparing enantiomerically pure 8-(3-aminopiperidin-1-yl)-xanthines.... Agent: Michael P. Morris Boehringer Ingelheim Usa Corporation

20090192315 - Synthesis of heterocyclic compounds: Methods for the synthesis of heterocyclic compounds including N-(3,5-dichloropyrid-4-yl)-4-difluoromethoxy-8-methanesulfonamido-dibenzo[b,d]furan-1-carboxamide and pharmaceutically acceptable salts thereof.... Agent: Forest Laboratories, Inc. Attn: Charles S. Ryan

20090187020 - Process and intermediate for preparation of donepezil: P

20090187021 - Indane compounds as ccr5 antagonists: The present invention relates to compounds of formula (I), or pharmaceutically acceptable derivatives thereof, useful in the treatment of CCR5-related diseases and disorders, for example, useful in the inhibition of HIV replication, the prevention or treatment of an HIV infection, and in the treatment of the resulting acquired immune deficiency... Agent: Glaxosmithkline Corporate Intellectual Property, Mai B482

20090187022 - Crystalline clopidogrel hydrobromide and processes for preparation thereof: Provided are crystalline forms of clopidogrel hydrobromide and processes for their preparation.... Agent: Kenyon & Kenyon LLP

20090187023 - Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl))-piperidine-2,6-dione: Polymorphic forms of 3-(4-amino-1-oxo-1,3 dihydro-isoindol-2-yl)-piperidine-2,6-dione are disclosed. Compositions comprising the polymorphic forms, methods of making the polymorphic forms and methods of their use are also disclosed.... Agent: Jones Day

20090187024 - Ropivacaine hydrochloride anhydrate and the preparation thereof: The invention pertains to a process for preparing stable anhydrous Ropivacaine hydrochloride, the process involving preparing Ropivacaine hydrochloride from Ropivacaine base, wherein Ropivacaine base is provided having a chiral purity of more than 95%, and wherein the isolation involves the use of isopropanol and hydrochloride, and is performed under water-free... Agent: Young & Thompson

20090187025 - Pharmaceutical composition for promoting angiogenesis: (wherein R represents a benzoyl group which may have, as substituents on the phenyl ring, 1 to 3 groups selected from a group consisting of an amino group, which may have a lower alkanoyl group, and a lower alkyl group; R1 represents a hydrogen atom or a lower alkyl group;... Agent: Finnegan, Henderson, Farabow, Garrett & Dunner LLP

20090187026 - Diastereomeric purification of rosuvastatin: The invention relates to diastereomerically pure rosuvastatin and processes for preparing diastereomerically pure rosuvastatin and its intermediates.... Agent: Kenyon & Kenyon LLP

20090182146 - Process for the preparation and purification of cis-2-methylspiro(1,3-oxathiolane-5,3')quiniclidine hydrochloride: An industrially acceptable process for the preparation and purification of cis-2-methylspiro(1,3-oxathiolane-5,3′)quiniclidine from a cisitrans mixture of isomers. Treatment of the mixture with an organic sulfonice acid generates a less soluble acid addition salt that is enriched in the cis-isomer. Recrystallization or pulping using various organic solvents allows for enrichment of... Agent: Apotex, Inc.

20090182147 - Process for the preparation of pure risedronic acid or salts: The present invention relates to an industrially advantageous process of making bisphosphonic acid or its salt in particular risedronic acid, [1-hydroxy-2(3-pyridinyl)ethylidene]bisphosphonic acid, having formula-(I) or its salts in high purity and high yields.... Agent: Law Offices Of Albert Wai-kit Chan, PLLC

20090182148 - Process for the manufacture of montelukast sodium: An improved process for the manufacture of 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropane acetic acid, sodium salt [montelukast sodium(I)]. It consists of converting a vital intermediate 1-(mercaptomethyl)-cyclopropane acetic acid of formula IX, to a quaternary ammonium salt of formula X, using a suitable base in a suitable solvent at 0° C. to 50° C. followed... Agent: Arent Fox LLP

20090182149 - Salt of sulfinylbenzimidazole compound, and crystal and amorphous form thereof: Salts of 2-[({4-[(2,2-dimethyl-1,3-dioxan-5-yl)methoxy]-3,5-dimethylpyridin-2-yl}methyl)sulfinyl]-1H-benzimidazole and their crystalline and amorphous forms.... Agent: Birch Stewart Kolasch & Birch

20090182150 - Novel intermediate for the preparation of paliperidone: l

20090176985 - Method for converting perylen-3,4:9,10-tetracarboxylic acid diimides into a form suitable for use as a fluorescent dye: P

20090176986 - Process for the preparation of pyridine heterocycle cgrp antagonist intermediate: An efficient syntheses for the preparation of the intermediate 2-oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine dihydrochloride, and other salt forms of 2-oxo-1-(4-piperidinyl)-2,3-dihydro-1H-imidazo[4,5-b]pyridine.... Agent: Merck And Co., Inc

20090176987 - Crystal form of quinoline compound and process for its production:

20090176988 - Preparation and use of magnesium amides: The present application relates to mixed Mg/Li amides of the general formula R1R2N—Mg(NR3R4)mX,m zLiY (II) wherein R1, R2, R3, and R4 are, independently, selected from H, substituted or unsubstituted aryl or heteroaryl containing one or more heteroatoms, linear, branched or cyclic, substituted or unsubstituted alkyl, alkenyl, alkynyl, or silyl derivatives... Agent: Jenkins, Wilson, Taylor & Hunt, P. A.

20090176989 - Processes for producing cycloalkylcarboxamido-pyridine benzoic acids: The present invention relates to a process of providing the 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid in substantially free form (Compound 1).... Agent: Vertex Pharmaceuticals Inc.

20090176990 - Process for producing nitroguanidine derivatives: wherein, in the formula, R2 represents an alkyl group having 1 to 4 carbon atoms; R3, R4, R5 and R6 each independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; and Q represents a 5- or 6-membered heterocyclic group which contains at least one... Agent: Buchanan, Ingersoll & Rooney PC

20090171087 - Platinum complex and organic light-emitting device using the same: wherein X, n, R1, R2, R3,R4, R5, X1, X2, L1, and L2 are defined the same as the specification. The present invention also further provides an organic light-emitting device using the same. The complexes of the present invention exhibit enhanced emission quantum yields, and short phosphorescence radiative lifetimes in the... Agent: Bacon & Thomas, PLLC

20090171088 - Reversible self-assembly of imbedded metallomacrocycles within a macromolecular superstructure: In accordance with the present invention, there is provided a method for preparing a reversible, self-assembly of an imbedded hexameric metallomacrocycle within a macromolecular superstructure. The method occurs by an intramolecular mechanism in which a macromolecular skeleton possesses multiple ligands capable of reversible assembly-disassembly triggered by the presence of metal... Agent: Hahn Loeser & Parks, LLP

20090171089 - 1,6 naphthridines useful as inhibitors of syk kinase:

20090171090 - Method for producing benzazepinone: It is an object of the present invention to provide 2-iminocarboxylic acid derivatives, and a practically suitable industrial method for producing benzazepinones in a short process under mild conditions. The present invention provides a method for producing a benzazepinone or a salt thereof, which comprises opening a ring of an... Agent: Greenblum & Bernstein, P.L.C

20090171091 - Compounds suitable as modulators of hdl: Disclosed herein in the embodiments of the present invention are the compounds suitable as modulators of HDL having general formula (1), novel intermediates involved in their synthesis, their pharmaceutically acceptable salts and pharmaceutical compositions containing them. The present invention also relates to a process of preparing compounds of general formula... Agent: Iphorgan, Ltd.

20090171092 - Process for the preparation of montelukast and its pharmaceutically acceptable salts: An improved process for the preparation of Montelukast and its pharmaceutically acceptable salts comprises of reacting (S) Benzenepropanol α-[3-[2-(7-chloro2-quinolinyl)ethenyl]phenyl]-2-(1-hydroxy-1-methyl ethyl)-α-methane sulfonate compound of formula (II) with 1-(mercapto methyl)cyclo propane acetic acid or its ester or nitrile in presence of alkali or alkaline carbonates and/or alkali or alkaline earth metal alkoxide... Agent: Hamilton, Brook, Smith & Reynolds, P.C.

20090171093 - 3'-fluoro-5'-hydroxythalidomide and derivatives thereof: wherein R1, R2 and R3 are each a hydrogen atom; and X is C═O, and an optically active substance thereof. As analogs of thalidomide, the 3′-fluoro-5′-hydroxythalidomide derivatives are useful in the treatment of erythema nodosum of Hansen's disease, prurigo, rheumatism, Crohn's disease, graft-versus-host disease, Behcet's disease, myeloma, aphtha ulcer and... Agent: Wenderoth, Lind & Ponack, L.L.P.

20090171094 - 1-benzyl-4-[(5, 6-dimethoxy- 1- indanon)- 2- yl]-methyl piperidine p-toluenesulfonate or crystal thereof: 1-Benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine p-toluenesulfonate or a solvate thereof.... Agent: Birch Stewart Kolasch & Birch

20090171095 - Production method of heterocyclic mercapto compound: A method of the invention industrially produces heterocyclic mercapto compounds useful as raw materials or intermediates in the synthesis of medicaments or pesticides, or as permanent wave agent, with a high yield and high productivity using easily available starting materials. A heterocyclic mercapto compound represented by Formula (1) (wherein X... Agent: Sughrue Mion, PLLC

20090171096 - Novel process for the preparation of roflumilast: The invention relates to novel processes for the preparation of high-purity roflumilast.... Agent: The Nath Law Group