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Organic compounds -- part of the class 532-570 series July category listing 07/09

20090192302 - 5'-modified bicyclic nucleic acid analogs: The present invention provides 5′-modified bicyclic nucleoside analogs and oligomeric compounds comprising at least one of these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 5′-carbon. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including for example enhanced nuclease... Agent: Jones Day For Isis Pharmaceuticals, Inc.

20090192303 - Nucleic acid extraction method: The present invention relates to a method for isolating nucleic acids from a nucleic acid containing sample, and a kit for carrying out said method. More specifically, it relates to a novel method for extracting nucleic acids from a nucleic acid containing sample, using an anion exchange solid support, and... Agent: Seed Intellectual Property Law Group PLLC

20090192304 - Product and process for transformation of thraustochytriales microorganisms: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, α-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as... Agent: Sheridan Ross P.C.

20090192305 - Ap2 transcription factors for modifying plant traits: This invention relates to polynucleotide and polypeptide transcription factor sequences that are of use for the transformation of plants. The AP2 transcription factors include G979, polynucleotide and polypeptide SEQ ID NOs: 1 and 2, respectively, and phylogenetically-related sequences.... Agent: Mendel Biotechnology, Inc.

20090187013 - Synthetic heparin pentasaccharides: Preparation of synthetic monosaccharides, disaccharides, trisaccharides, tetrasaccharides and pentasaccharides for use in the preparation of synthetic heparinoids.... Agent: Morrison & Foerster LLP

20090187014 - Novobiocin analogues: Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders, as well as cancer.... Agent: Stinson Morrison Hecker LLP Attn: Patent Group

20090187015 - Process for preparing substituted benzimidazole compounds: The invention relates to new methods of preparing substituted benzimidazole compounds, such as 2-bromo-5,6-dichlorobenzimidazole, which are useful in the preparation of compounds having antiviral activity.... Agent: Glaxosmithkline Corporate Intellectual Property, Mai B482

20090187016 - Method for producing cellulose acetals: The present invention describes a process for preparing acetals of polysaccharides, oligosaccharides or disaccharides by dissolving these in at least one ionic liquid and reacting them with a vinyl ether. The acetalated polysaccharides or oligosaccharides obtained in this way can be crosslinked by treatment with acid. The present invention also... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20090182132 - Rectangular parallelepipedal maltitol: The invention concerns maltitol crystals, characterized in that they have a rectangular parallelepipedal shape and have a length to width dimensional ratio in the range 1.8 to 5.3, preferably 3±0.7, and a process for producing them.... Agent: Young & Thompson

20090182133 - Benzopyranone derivatives and their use as anti-viral agents: The invention relates to pharmaceutical compositions comprising benzopyranone derivatives for the treatment of Severe Acute Respiratory Syndrome (SARS).... Agent: K&l Gates LLP

20090182135 - Amino modifiers: e

20090182134 - Sirna targeting phosphatases: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20090182136 - Small internally segmented interfering rna: The present invention is directed to pharmaceutical and therapeutic compositions which comprise RNA complexes comprising an antisense strand and a discontinued passenger strand capable of regulating gene expression. The use of a discontinued passenger strand reduces off target effects of the RNA complexes and also has other advantages.... Agent: Fish & Richardson PC

20090182137 - Vesicle for separating substances from liquid media: The invention relates to methods of separating substances from liquid media and to separating agents suitable therefor.... Agent: Sughrue Mion, PLLC

20090182138 - Method for acylating cellulose with a specific average degree of polymerization: e

20090176974 - Method of aralkylation of 4'-hydroxyl group of anthracylins: A method for the aralkylation of anthracyclins by utilizing an aralkylating agent R3-CH2X (for example, BnBr) in accordance with the reaction pathway describe by the scheme shown in FIG. 1. The present invention recognizes that 4-R1, 3′-N3-Daunomycines are suitable substrates for selective 4′-O-benzylation, yielding 4-R1, 3′-N3-4′-O-Aralkyl-Daunorubicines (in particular, 4′-O-Bn-Daunomycines). Thus,... Agent: VistaIPLaw Group LLP

20090176975 - Methods and compositions for detecting promoter activity and expressing fusion proteins: The present invention provides nucleic acid molecules comprising one or more nucleic acid sequences encoding a polypeptide having a detectable activity. The present invention also provides methods of joining such nucleic acid molecules to nucleic acid molecules to be assayed for promoter activity. The present invention also relates to methods... Agent: Invitrogen Corporation C/o Intellevate

20090176976 - Nitrilases: The invention relates to nitrilases and to nucleic acids encoding the nitrilases. In addition methods of designing new nitrilases and method of use thereof are also provided. The nitrilases have increased activity and stability at increased pH and temperature.... Agent: Verenium C/o Mofo S.d.

20090176977 - Lna modified phosphorothiolated oligonucleotides: The current invention provides oligonucleotides which comprise a dinucleotide consisting of a 5′ locked nucleic acid (LNA), a phosphorothioate internucleoside linkage bond to a 3′ RNA or RNA analogue. The dinucleotide reduces the strength of hybridization of the oligonucleotide to a complementary nucleic acid target. The modification can be used... Agent: Fish & Richardson PC

20090176978 - Quarternized amino glucosamine compound for exerting anticancer effect: The present invention relates to the quarternized amino glucosamine, it can exert an anticancer effect via induction of apoptosis in a dose and time dependant manner through which an anticancer treatment effect can be increased.... Agent: Birch Stewart Kolasch & Birch

20090176979 - Process for production of polysaccharide and/or monosaccharide by hydrolysis of different polysaccharide: The object is to produce a polysaccharide and/or a monosaccharide efficiently by hydrolyzing a different polysaccharide efficiently. The hydrolysis of a polysaccharide is an important means for producing a monosaccharide that can be used as a starting material for the production of ethanol, the solubilization of a water-insoluble polysaccharide, and... Agent: Birch Stewart Kolasch & Birch

20090171074 - Flavonoid compound having an antiviral activity: The present invention relates to a flavonoid compound having an antiviral activity, more particularly to a flavonoid compound obtained by extracting Houttuynia cordata with methanol and separating/purifying with chromatography, a method for efficient extraction and purification of the same and an antiviral composition comprising the compound as an active ingredient.... Agent: Frommer Lawrence & Haug

20090171075 - Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo: Preparations of novel molecular transporter compositions and their use for transporting bioactive substances into cells in living animals are disclosed. To afford in vivo delivery, the composition is covalently linked to the bioactive substance and the resultant composite structure is introduced into the subject. The transporter composition includes multiple guanidine... Agent: Teri G. Andrews Attorney At Law

20090171076 - Compositions and methods for the use of fmoc derivatives in dna/rna synthesis: Methods of nucleic acid preparation are described, including preparation of MnRNA, using FMOC derivatives to synthesize oligonucleotides in addition to applying FMOC protocols to various therapeutic and diagnostic methods. In some embodiments a single stranded oligonucleotide is synthesized bound to a polymer support (such as optic fiber glass filters) using... Agent: King & Spalding LLP

20090171077 - Delivery of nucleic acid-like compounds: A process for preparing a microparticulate complex is provided. The process comprises (a) combining a particle-forming component (“PFC”) and a nucleic acid-like component (“NAC”) in a monophasic composition comprising water and a water-miscible, organic solvent to form a mixture wherein the PFC and the NAC are independently molecularly or micellarly... Agent: Foley & Lardner LLP

20090171078 - Method of sequencing nucleic acids using elaborated nucleotide phosphorotiolate compounds: The present teachings provide methods, compositions, and kits for synthesizing and sequencing nucleic acids. In some embodiments, elaborated nucleotide phosphorothiolate compounds are employed along with efficient cleaving reactions. Improved sequencing efficiency is achieved by the rapid polymerase-mediated incorporation of elaborated nucleotide phosphorothiolate compounds. Increased sequencing efficiency is also achieved by... Agent: Mila Kasan, Patent Dept. Applied Biosystems

20090171079 - 6-position highly acetylated cellulose diacetate and process for producing the same: e