Organic compounds -- part of the class 532-570 series inventions 06/09

20090163700 - Granulated maltitol for direct compression and method of preparation thereof: The invention relates to a granulated maltitol of concentration greater than or equal to 97%, preferably between 98 and 99%, characterized in that it has a water content less than 1%, preferably less than 0.5%, more preferably less than or equal to 0.4%, a compressibility greater than or equal to... Agent: Young & Thompson

20090163702 - Sirna targeting myeloid cell leukemia sequence 1: Efficient sequence specific gene silencing of myeloid cell leukemia sequence 1 is possible through the use of siRNA technology. By selecting particular siRNAs directed to myeloid cell leukemia sequence 1 by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing... Agent: Kalow & Springut LLP

20090163701 - Sirna targeting tumor necrosis factor receptor superfamily member 1a: Efficient sequence specific gene silencing of siRNA targeting tumor necrosis factor receptor superfamily member 1A is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes.... Agent: Kalow & Springut LLP

20090163703 - Phase difference plate comprising polymer film containing compound having rod-shaped molecular structure: A phase difference plate which comprises one sheet of polymer film containing a compound having a rod-shaped molecular structure and exhibiting a maximum absorption wavelength (λmax) of less than 250 nm in an ultraviolet spectrum of its solution and which exhibits a retardation value as measured at a wavelength of... Agent: Buchanan, Ingersoll & Rooney PC

20090163704 - Use of acid scavengers in removal of protons (acidity) of the reaction mass during chlorination of sucrose-6-acetate: A process is described wherein efficiency of chlorination is improved in a process for production of a chlorinated sucrose by scavenging, using an acid scavenger, of excess of acidic protons formed during a chlorination reaction between 6-O-acyl sucrose in dimethylformamide and a chlorinating reagent.... Agent: The Nath Law Group

20090156792 - Bis-modified bicyclic nucleic acid analogs: The present disclosure describes bis-modified bicyclic nucleosides and oligomeric compounds that can be prepared comprising at least one of these bis-modified bicyclic nucleosides. More particularly, the bis-modified bicyclic nucleosides have at least one substituent group at the 5′-methylene and on the bridge methylene and can be chiral. These bis-modified bicyclic... Agent: Jones Day For Isis Pharmaceuticals, Inc.

20090156793 - Circular chromosomes: Circular chromosomes with centromere DNA comprise recombination sites flanking a region with bacterial replication DNA and a recombinase transcription unit. Circular chromosomes without bacterial replication DNA are formed by removing bacterial replication DNA from a circular chromosome by action of a recombinase that excises DNA between said recombination sites.... Agent: Monsanto Company

20090156794 - Compositions and methods for activating genes of interest: Compositions and methods for activating genes of interest are provided. The compositions comprise a masked targeted expression cassette which expresses a gene product only in the presence of a target molecule. The cassettes are useful for the treatment of disease and for preventing the proliferation of neoplastic cells.... Agent: Charles A. Black

20090156795 - Zsig33-like polynucleotides: The present invention relates to polynucleotide related to the zsig33 peptide, including agonists, antagonists, and antibodies. Methods of modulating gastric contractility, nutrient uptake, growth hormones, the secretion of digestive enzymes and hormones, and/or secretion of enzymes and/or hormones in the pancreas are also included.... Agent: Zymogenetics, Inc. Intellectual Property Department

20090156796 - Metastatic colon cancer specific promoter and uses thereof: Colon cancer specific promoter sequences and adenovirus vehicles are provided. By providing for transcriptional initiating regulation dependent upon transcription factors that are only active in specific, limited cell types, virus replication will be restricted to the target cells. The modified adenovirus may be used as a vehicle for introducing new... Agent: Ropes & Gray LLP

20090156797 - Sirna targeting hypoxia-inducible factor 1: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed.... Agent: Kalow & Springut LLP

20090156798 - Process for producing cation exchangers: Strongly acidic cation exchangers with high mechanical, osmotic and oxidation stability can be prepared by sulfonating bead polymers formed from one or more vinylaromatic monomer(s), one or more crosslinker(s) and from 0.2 to 20% by weight of one or more vinyl ethers and/or vinyl esters.... Agent: Lanxess Corporation

20090149640 - Nucleic acid ladders: The present invention provides nucleic acid molecules which may be used as standards for estimating the size (in base pairs) and mass of linear, double-stranded or single-stranded nucleic acid molecules separated by size. The nucleic acid molecules of the invention may be DNA molecules, RNA molecules or DNA/RNA hybrid molecules,... Agent: Invitrogen Corporation C/o Intellevate

20090149641 - Fish disease protection: The present invention concerns genes associated with viral disease in fish, particularly fish from the family Salmonidae, and more particularly Atlantic salmon.... Agent: Christian D. Abel

20090149642 - Enriched preparation of human fetal multipotential neural stem cells: The present invention relates to a method of separating multipotential neural progenitor cells from a mixed population of cell types. This method includes selecting a promoter which functions selectively in the neural progenitor cells, introducing a nucleic acid molecule encoding a fluorescent protein under control of said promoter into all... Agent: Nixon Peabody LLP - Patent Group

20090149643 - Aptamers to von willebrand factor and their use as thrombotic disease therapeutics: The invention relates generally to the field of nucleic acids and more particularly to aptamers capable of binding to von Willebrand Factor useful as therapeutics in and diagnostics of thrombotic diseases and/or other diseases or disorders in which von Willebrand Factor mediated platelet aggregation has been implicated. The invention further... Agent: Mintz, Levin, Cohn, Ferris, Glovskyand Popeo, P.C.

20090149644 - Sirna targeting kras: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs directed to silencing KRAS, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes.... Agent: Kalow & Springut LLP

20090149645 - Method for detaching protecting group on nucleic acid: A method is provided for removing a 2-cyanoethoxymethyl (CEM) group and substituting the 2′-hydroxyl group of each ribose of an oligonucleic acid derivative with good reproducibility and high efficiency.... Agent: Darby & Darby P.C.

20090149646 - Isolation of nucleic acid: The present invention provides a method of isolating nucleic acid from a sample, said method comprising contacting said sample with a detergent and a solid support, whereby soluble nucleic acid in said sample is bound to the support, and separating said support with bound nucleic acid from the sample. Where... Agent: Invitrogen Corporation C/o Intellevate

20090149639 - A simplified method to retrieve chitosan from acidic solutions thereof: Compositions of salted out chitosan polymer containing mixture of certain salting out salts as well as methods for making and using same are disclosed. Chitosan polymer preparations produced by such methods are substantially free of chitosanase, undesirable salts and excess acid and retain their physiological as well as biological and... Agent: Choate, Hall & Stewart LLP

20090149647 - Process for production of lipid a analogue: Discloses is a process for producing α-D-glucopyranose, 3-O-decyl-2-deoxy-6-O-[2-deoxy-3-O-[(3R)-3-methoxydecyl]-6-O-methyl-2-[(11Z)-1-oxo-11-octadecenyl]amino]-4-O-phosphono-β-D-glucopyranosyl]-2-[(1,3-dioxotetradecyl)amino]- or 1-(dihydrogen phosphate) tetrasodium salt which is useful as an active ingredient of a pharmaceutical or an intermediate for the synthesis thereof, which is environment-friendly and excellent in safety, operationality and reproducibility. A process for producing a compound represented by the formula... Agent: Birch Stewart Kolasch & Birch

20090143571 - Novel genes and their use in the modulation of obesity, diabetes and energy imbalance: The present invention relates generally to nucleic acid molecules encoding proteins associated with the modulation of obesity, diabetes and/or metabolic energy levels. More particularly, the present invention is directed to nucleic acid molecules and the recombinant and purified proteins encoded thereby and their use in therapeutic and diagnostic protocols for... Agent: Scully Scott Murphy & Presser, PC

20090143572 - Method for seperating and purifying rna: A method for separating and purifying RNA including the steps of passing a sample solution containing a nucleic acid, a washing solution and a recovering solution through a nucleic acid-adsorbing porous membrane to adsorb nucleic acid, adsorbing, washing and recovering, in which the nucleic acid adsorbing porous membrane is a... Agent: Birch Stewart Kolasch & Birch

20090143573 - Reactor pump for catalyzed hydrolytic splitting of cellulose: A reactor for hydrolytic splitting of cellulose under high pressure and heat has an inlet and outlet each with a cross-sectional area smaller than the cross-sectional area of the reactor. The pressure and heat in the reactor forms a cellulose plug within the inlet and the outlet. The inlet plug... Agent: Pauly, Devries Smith & Deffner, L.L.C.