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Organic compounds -- part of the class 532-570 series May archived by USPTO category 05/09

20090137798 - Process for the preparation of delmopinol and derivatives thereof: A process for the preparation of delmopinol (3-(4-propylheptyl)-4-morpholinethanol) or a derivative or a pharmaceutically acceptable salt, or a solvate thereof, including an hydrate, comprises reacting oxazolidin [2, 3-c] morpholine and a grignard reagent, and optionally converting the delmopinol (or derivative) free base into a pharmaceutically acceptable salt. The oxazolidin [2,... Agent: Saliwanchik Lloyd & Saliwanchik A Professional Association

20090137799 - Cycloalkylcarbonylamino acid ester derivative and process for producing the same: p

20090137800 - Novel compound, optical filter and optical recording material using the same: wherein ring A and ring B each independently represent a benzene, naphthalene, or heterocyclic ring which may be substituted; R1 and R2 each independently represent an alkyl group having 1 to 8 carbon atoms which may be substituted; R1 and R2 may be linked together to form a ring; a... Agent: Young & Thompson

20090137801 - 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions: e

20090137802 - A2b adenosine receptor antagonists: Disclosed are processes for the synthesis of novel compounds that are A2B adenosine receptor antagonists, useful for treating various disease states, including asthma and diarrhea.... Agent: Cv Therapeutics, Inc.

20090137803 - 5-protected aminopyrimidine compound, production method thereof and intermediate therefor: The present invention provides a production method of 5-aminopyrimidine compound represented by the formula (5) by reacting a glycine compound represented by the formula (1) with t-butoxybisdimethylaminomethane, dimethylformamidedimethylacetal or dimethylformamidediethylacetal to produce a dialkylaminomethylene compound represented by the formula (2), reacting the compound of formula (2) in the presence of... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20090137804 - Compounds and compositions as protein kinase inhibitors: wherein the substituents X1, R1, R2, R3 and R4 have the meaning as set forth and explained in the description of the invention, to processes for the preparation of these compounds, pharmaceutical compositions containing same, the use thereof optionally in combination with one or more other pharmaceutically active compounds for... Agent: Novartis Corporate Intellectual Property

20090137805 - N-phenyl-2-pyrimidine-amine derivatives: The present invention relates to novel amides and a process for preparing these amides.... Agent: Novartis Corporate Intellectual Property

20090137806 - Dual nk1/nk3 receptor antagonists: wherein the substituents are as described herein or a pharmaceutically active acid-addition salt thereof. In particular, the invention provides methods for treating both positive and negative symptoms of schizophrenia through dual inhibition of NK1 and NK3 receptors. The invention also provides novel compounds with formula I and methods for preparing... Agent: Hoffmann-la Roche Inc. Patent Law Department

20090131659 - Amide compound and thrombopoietin receptor activator: P

20090131660 - Synthesis of 3-[4-(1,1-dimethyl-propyl)-phenyl]-2-methyl-propionaldehyde and cis-4--2,6-dimethyl-morpholine (amorolfine):

20090131661 - Oxazolone derivatives:

20090131662 - Compositions and methods pertaining to pna synthons and oligomers comprising a universal base: This invention is related to compositions and methods pertaining to PNA synthons, PNA oligomers and/or PNA/DNA Chimeras comprising a universal base.... Agent: Invitrogen Corporation C/o Intellevate

20090131663 - Process for preparing substituted 5-amino-pyrazolo-[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines: A process for preparing substituted 5-amino-pyrazolo[4,3-e]-1,2,4-triazolo-[1,5-c]pyrimidine compounds having an aminoalkyl substituent at the 7-position is disclosed.... Agent: Schering-plough Corporation Patent Department (k-6-1, 1990)

20090131664 - Method for producing 4(3h)-quinazolinone derivative: This invention is related to a method for producing 3-{4-[3-(1-pyrrolidinyl)propoxy]phenyl}-5-trifluoromethyl-4(3H)-quinazolinone comprising a step for reacting 2-methyl-5-trifluoromethyl-4H-3,1-benzoxazin-4-one with 4-[3-(1-pyrrolidinyl)propoxy]aniline or an acid-addition salt thereof, or 4-(1-cyclobutyl-4-piperidinoy9oxyaniline or acid addition salt thereof in the presence of an acid catalyst.... Agent: Merck And Co., Inc

20090131666 - Acylaminopiperidine compound: i

20090131665 - Process for the preparation of crystalline forms a, b and pure crystalline form a of erlotinib hci: The invention provides processes for preparing crystalline Forms A, B and pure crystalline Form A of Erlotinib hydrochloride.... Agent: Merchant & Gould PC

20090131667 - Polymorphic forms of tadalafil: Polymorphic forms of tadalafil, and processes for their preparation.... Agent: Dr. Reddy''s Laboratories, Inc.

20090131668 - 4-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds: l

20090124801 - Process for synthesizing phosphonic and phosphinic acid compounds: The present invention is directed to an improved process for synthesizing phosphonic and phosphinic acid chymase inhibitor compounds.... Agent: Philip S. Johnson Johnson & Johnson

20090124802 - Diaryl-purines, azapurines and -deazapurines as non-nucleoside reverse transcriptase inhibitor for treatment of hiv: This application concerns certain 2-phenylamino-6-aryl amino-, 6-aryloxy-, and 6-arylthio-purines, -azapurines and -deazapurines. These compounds are non-nucleoside reverse transcriptase inhibitors and have potential as anti-HIV treatment.... Agent: Wilson Sonsini Goodrich & Rosati

20090124803 - Process for preparation of rosuvastatin: The invention relates to commercially viable process for the preparation of Rosuvastatin by an early introduction of the correct absolute stereochemistry at C-5 (S) of Rosuvastatin side chain followed by regioselective chain extension using novel side chain building blocks. It is yet another object of the invention is to provide... Agent: Rader, Fishman & Grauer PLLC

20090124804 - Enantioselective process for preparing a substituted alkanoic acid: The present invention is directed to a process for enantioselectively preparing substituted piperidine alkanoic acid integrin antagonist compounds.... Agent: Philip S. Johnson Johnson & Johnson

20090118498 - Ozonolysis reactions in liquid co2 and co2-expanded solvents: A method for increasing ozone concentration in a liquid can include: providing a gas having ozone; introducing the ozone-containing gas into a liquid, wherein the liquid and ozone combination has a temperature between about 0.8 and about 1.5 times the critical temperature of ozone; and increasing isothermally, the pressure of... Agent: Workman Nydegger 1000 Eagle Gate Tower

20090118499 - 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitors: and pharmaceutically acceptable salts thereof, wherein X1, X2, X3, X4, X5, X6, X7, R1, and Q1 are defined herein, inhibit the IGF-1R enzyme and are useful for the treatment and/or prevention of hyperproliferative diseases such as cancer, inflammation, psoriasis, allergy/asthma, disease and conditions of the immune system, disease and conditions... Agent: Osi Pharmaceuticals, Inc.

20090118500 - Thiophene compounds and thrombopoietin receptor activators: A compound represented by the formula (I) (wherein R1, R2, R3 and R4 are as defined in the description), a tautomer, prodrug or pharmaceutically acceptable salt of the compound or a solvate thereof.... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20090118501 - Dicycloalkyl urea glucokinase activators: Dicycloalkyl urea glucokinase activators compounds are glucokinase inhibitors useful for the treatment of diabetes.... Agent: Novo Nordisk, Inc. Intellectual Property Department

20090118502 - Biaryl heterocyclic compounds and methods of making and using the same: The present invention relates generally to the field of anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. More particularly, the invention relates to a family of compounds having both a biaryl moiety and at least one heterocylic moiety that are useful as such agents.... Agent: Mintz, Levin, Cohn, Ferris, Glovsky And Popeo, P.c

20090118503 - Faah inhibitors: Indole derivatives that are useful for treating pain, inflammation and other conditions are described. Certain of the compounds are benzyl derivatives and others are benzoyl derivatives. The compounds are substituted at least at the 3 position of the indole.... Agent: Fish & Richardson PC

20090118504 - Novel phosphonic acid compounds as inhibitors of serine proteases: The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.... Agent: Philip S. Johnson Johnson & Johnson

20090118505 - Process for the preparation of substituted phenylalanines: Intermediates and synthetic processes for the preparation of substituted phenylalanine-based compounds (e.g., of Formula I) are disclosed:... Agent: Lexicon Pharmaceuticals, Inc.

20090118506 - 6,11-bridged biaryl macrolides: which exhibit antibacterial properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of antibiotic treatment. The invention also relates to methods of treating a bacterial infection in a subject by administering a pharmaceutical composition comprising the compounds of the... Agent: Elmore Patent Law Group, PC

20090118507 - Method for preparing (3-chloro-4-fluorophenyl)-(4-fluoro-4--piperidin-1-yl)-methanone and novel intermediate pyrimidine derivatives: The present invention concerns the method for preparing (3-chloro-4-fluorophenyl)-(4-fluoro-4-{[(5-methyl-pyrimidin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-methanone of formula (II) by condensation between 5-methyl-pyrimidin-2-methylamine of formula (I) and cyanohydrin of formula (III).... Agent: Birch Stewart Kolasch & Birch

20090118508 - Novel phosphonic acid compounds as inhibitors of serine proteases: The present invention is directed to phosphonic acid compounds useful as serine protease inhibitors, compositions thereof and methods for treating inflammatory and serine protease mediated disorders.... Agent: Philip S. Johnson Johnson & Johnson

20090118509 - Preparation of [2-methyl-5-phenyl-3-(piperazin-1-ylmethyl)] pyrrole derivatives: e

20090118510 - Dark coloured azo dyes: