Organic compounds -- part of the class 532-570 series inventions 02/09

20090054634 - Process for the preparation of clarithromycin: The present invention includes a process involving a one-pot reaction for preparing erythromycin 9-oxime salt comprising: (a) reacting erythromycin thiocyanate with an ammonium source to obtain erythromycin free base; (b) oximating the C-9 carbonyl of the erythromycin free base by reacting the erythromycin free base with triethylamine and hydroxyl amine... Agent: Kenyon & Kenyon LLP

20090054635 - Corn inbreds like far601 and hybrids thereof: A maize inbred line having the characteristics selected from those of FAR601, including plant parts, tissue, and pigments of the inbred is disclosed.... Agent: Patterson, Thuente, Skaar & Christensen, P.A.

20090054636 - Primers for exons of variants of rhce and rhd genes: Disclosed are a method and an algorithm for genetic cross-matching based on the comparison of recipient and donor genotypes—and the underlying combinations of alleles and haplotypes. The method of the invention, rather than focusing on phenotype prediction, instead relies on a comparison of genetic variants identified in the recipient and... Agent: Eric P. Mirabel

20090054637 - Thermoplastic resin film and method for producing the same: The present invention provides a thermoplastic resin film which has uniform optical properties and can be used for a high quality functional film and a method for producing the same to suppress uneven thickness in the machine direction of a film and streaks in the film. The method for producing... Agent: Sughrue Mion, PLLC

20090054638 - Cellulose ester compositions having low bifringence and films made therefrom: The present invention relates to cellulose esters having low hydroxyl content for use in optical applications, such as liquid crystal display (LCD) films. Films made with low hydroxyl levels and a given ratio of non-acetyl ester to hydroxyl level have been found to have low intrinsic birefringence. Therefore, these films... Agent: Betty Joy Boshears Eastman Chemical Company

20090054639 - Process for the manufacture of oxidized starch, oxidized starch and its use: Process for the manufacture of oxidized starch by reacting an aqueous slurry of starch with a peroxide compound, the reaction being carried out in the presence of ozone or by irradiating the slurry with UV light, the amount of peroxide compound used being lower than 30 % by weight calculated... Agent: Solvay C/o B. Ortego - Iam-nafta

20090054640 - Device and method for the control of chemical processes: The present invention provides a method of controlling a chemical process, the method comprising the steps of: (i) providing a laminar flow of a first fluid, the first fluid providing a first reagent or one or more precursor thereof), a laminar flow of a second fluid, the second fluid providing... Agent: Frommer Lawrence & Haug

20090048434 - Compositions and methods relating to orthogonal ribosome mrna pairs: Orthogonal ribosome orthogonal mRNA pairs are provided, as are methods for their selection involving a novel positive-negative selection approach, and methods for their use. Also provided are cellular logic circuits involving orthogonal ribosomes.... Agent: Edwards Angell Palmer & Dodge LLP

20090048435 - Oligonucleotide modulation of cell adhesion: Compositions comprising oligonucleotides which are specifically hybridizable with nucleic acids encoding cellular adhesion molecules intracellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and endothelial leukocyte adhesion molecule-1 (ELAM-1) are disclosed. A series of double stranded RNA molecules targeting human ICAM-1 were designed and inhibition of RNA was measured. Oligonucleotides... Agent: Knobbe, Martens, Olson & Bear, LLP

20090048436 - Methods of synthesizing chemically cleavable phosphoramidite linkers: The present invention provides a method of synthesizing phosphoramidite linkers that are useful for the production of synthesizing two or more oligonucleotides in tandem. The inventive linker has the following desirable properties: (i) enhanced stability to alkali conditions versus the linkers previously published, (ii) cleaves to produce 5′ and 3′... Agent: Thompson Hine L.L.P. Intellectual Property Group

20090048437 - Method of purifying rna using kosmotropic salt: The present invention provides a method of purifying RNA, including contacting a solid support with an acidic solution having a RNA-containing sample and a kosmotropic salt having a concentration of less than 1M, thereby binding the RNA to the solid support. According to the present invention, RNA is purified efficiently... Agent: Sughrue Mion, PLLC

20090048439 - Isolation of nucleic acids molecules using modified solid supports: Provided are solid supports that contain at least one hydrophilic ligand; and at least one hydrophobic ligand, where amount of the at least one hydrophobic ligand on the solid support relative to the amount of the at least one hydrophilic ligand on the solid support is adjusted for binding target... Agent: Bell, Boyd & Lloyd LLP

20090048438 - Method for washing a column and method for extracting membrane-bound target molecules: A method for washing a column is characterised by using a washing liquid, such as an eluting buffer, water, or even any expected buffer, between the traditional washing step and the eluting step as to effectively remove the impurities and/or residual washing liquid in a column from the previous washing... Agent: Ladas & Parry LLP

20090048440 - Nucleotide sugar purification using membranes: The invention provides methods of removing contaminants from a mixture of a desired product and contaminants by pH adjustments and molecular weight cut-offs. The contaminants include phosphate groups, magnesium sulfate, sodium pyruvate and tetrasodium pyrophosphate groups. The desired product includes nucleotide sugars, glycolipids, LnNT, sialyl lactose, and salts.... Agent: Morgan, Lewis & Bockius LLP (sf)

20090043083 - Methods and compositions for the specific inhibition of gene expression by double-stranded rna: The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as for treating diseases caused by the expression of the gene. More particularly, the invention is directed to compositions that contain double stranded... Agent: Rothwell, Figg, Ernst & Manbeck, P.C.

20090043082 - Microrna and methods for inhibiting same: The invention relates to isolated DNA or RNA molecules comprising at least ten contiguous bases having a sequence in a pancreatic islet microRNA. In another embodiment, the invention relates to isolated single stranded pancreatic islet microRNA molecules or anti-pancreatic islet microRNA molecules.... Agent: Hoffmann & Baron, LLP

20090043085 - Methods and compositions for the specific inhibition of gene expression by double-stranded rna: The invention is directed to compositions and methods for selectively reducing the expression of a gene product from a desired target gene in a cell, as well as for treating diseases caused by the expression of the gene. More particularly, the invention is directed to compositions that contain double stranded... Agent: Rothwell, Figg, Ernst & Manbeck, P.C.

20090043084 - Sirna targeting minichromosome maintenance deficient 3 (mcm3): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20090043086 - Methods for synthesizing a collection of partially identical polynucleotides: Methods for synthesizing a collection of partially identical polynucleotides are disclosed.... Agent: Philip S. Johnson Johnson & Johnson

20090043087 - Dna purification and recovery from high particulate and solids samples: This invention relates to methods for rapid nucleic acid purification from sources heavily contaminated with high particulate material, such as cellular debris, and solids, including suspended solids. In particular, this invention provides methods for rapid, quantifiable recovery and purification of nucleic acids from a variety of sources heavily contaminated with... Agent: David G. Conlin Edwards Angell Palmer & Dodge LLP

20090043088 - Cellulose ester and production method thereof: A cellulose ester and film thereof useful for remarkably improving optical properties such as optical isotropy are provided. The cellulose ester is adjusted so that the degree of substitution is from 2.90 to 2.965, the total of degrees of substitution at 2- and 3-positions is not less than 1.97, and... Agent: Birch Stewart Kolasch & Birch

20090043089 - Method for preparing polyanhydroglucuronic acid and/or salts thereof: A method for preparing polyanhydroglucuronic acid and/or salts thereof is described. A polyanhydroglucuronic acid-containing material obtained by oxidation is subjected to partial or complete hydrolysis to form a homogeneous system, subsequent ion exchange in the homogeneous system; and supplemental oxidation in the presence of any one or more of organic... Agent: Jacobson Holman PLLC