Organic compounds -- part of the class 532-570 series inventions 11/08

20080293952 - Method for the preparation of (s)-n-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine hydrochloride (duloxetine): A method of preparation of (S)—N-methyl-3-(1-naphthyloxy)-3-(2-mienyl)propylamine of Formula (I) and its pharmaceutically acceptable salts, comprising a) reaction of (RS)—N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine with optically active D-tartaric acid or an acid salt derived from D-tartaric acid forming a mixture of diastereoisomeric salts of N,N-dimethyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine and D-tartaric acid (2:1), b) isolation of the salt (S)—N,N-dimethyl-3-(naphthyloxy)-3-(2-thienyl)propylamine/D-tartrate... Agent: Pearl Cohen Zedek Latzer, LLP

20080293953 - Chiral spiro compounds and their use in asymmetric catalytic reactions: X and X′ can be independently O, NH, NR, NCOR or S; each of Z1-Z7 and Z1′-Z7′ can be independently H, alkyl, aryl, substituted alkyl, substituted aryl, alkoxyl, aryloxyl, nitro, amide, aryloxide, halide, hydroxyl, carboxylate, heteroaryl, or a cyclic alkene, fused aryl, or cyclic ether group formed from any two... Agent: Paul D. Greeley, Esq. Ohlandt, Greeley, Ruggiero & Perle, L.L.P.

20080293954 - Process for synthesizing trioxymethylene using ionic liquid: The present invention relates to a process for synthesizing trioxymethylene, wherein an aqueous solution of formaldehyde is used as the reactant; and an acidic ionic liquid in an amount of from 0.01 to 10 wt % is used as a catalyst.... Agent: Heslin Rothenberg Farley & Mesiti PC

20080293955 - Method for producing vitamin e-adsorbates: The present invention relates to a process for preparing adsorbates of at least one vitamin E compound in adsorbed form on a silica support, comprising, as the essential step, the mixing of the corresponding vitamin E compound with the silica support under reduced pressure. The invention further relates to adsorbates... Agent: Connolly Bove Lodge & Hutz, LLP

20080287692 - Synthesis of cyclopentadiene derivatives: P

20080287693 - Process for the preparation of 1-naphthol mixed ethers and intermediates of crystalline forms of (+) and (-)-duloxetine: The invention relates to a process for the preparation of duloxetine (1a), comprising the reaction between 1-fluoronaphthalene and 3-N,N-dimethylamino-1-(2-thienyl)-propan-1-ol in the presence of 1,3-dimethyl-2-oxo-hexahydropyrimidine (DMPU) as the solvent; a method for the identification of duloxetine enantiomers and for the determination of its optical purity is also disclosed.... Agent: Arent Fox LLP

20080287694 - Processes for producing a fluorosulfonyl group-containing compound and a compound led from the fluorosulfonyl group-containing compound: wherein RA is a bivalent organic group such as a fluoroalkylene group, RAF is a group having RA fluorinated, or the same group as RA, each of RB to RD which are independent of one another, is a hydrogen atom, etc., each of RBF to RDF is a fluorine atom,... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20080287695 - Agent for optical resolution, process for producing optically active substance and 1,5-substituted bicyclo [3.3.0] -2-oxaoctane compound: An agent for optical resolution comprising a bicyclo[3.3.0]-2-oxaoctane compound represented by the formula [1], [2] or [3] a process for producing an optically active substance comprising obtaining a mixture of diastereomers by reaction of the agent with a mixture of optically active substances having active hydrogen atom, resolving the mixture... Agent: Kratz, Quintos & Hanson, LLP

20080287696 - Process for the preparation of synthetic taxanes: The present invention relates to a process for the preparation of synthetic taxanes, which protects C(7)-OH with lanthanon compounds. Its advantages are simple process and firm & reliable binding. Moreover, no C(7)-acylated taxanes are produced in the subsequent steps, and hydrolysis of C(2′)-ester groups in acylated products becomes readily controllable.... Agent: Beyer Law Group LLP

20080281108 - Chiral compounds: The invention relates to chiral compounds, methods of their preparation, and to their use in optical, electrooptical, electronic, semiconducting or luminescent components or devices, and in decorative, security, cosmetic or diagnostic applications.... Agent: Millen, White, Zelano & Branigan, P.C.

20080281109 - Integrated method for the production of trioxane from formaldehyde: The invention relates to an integrated process for preparing trioxane from formaldehyde in which, in a first step, a stream A1 comprising water and formaldehyde and a recycle stream B2 consisting substantially of water and formaldehyde are fed to a trioxane synthesis reactor in which the formaldehyde is converted to... Agent: Connolly Bove Lodge & Hutz, LLP

20080281110 - Process for resolving citalopram: The (S)-citalopram content of a mixture of (R)- and (S)-citalopram can be enriched by using L-tartaric acid as the resolving agent in the presence of formaldehyde.... Agent: SynthonIPInc

20080281111 - Process for preparation of mycophenolate mofetil and other esters of mycophenolic acid: Provided are processes for the preparation of mycophenolate mofetil and other esters of mycophenolic acid.... Agent: Kenyon & Kenyon LLP

20080275254 - Process for polymerizing 1-butene: A process for polymerizing 1-butene, optionally with up to 30% by mol of ethylene, propylene or an alpha olefin of formula CH2═CHT wherein T is a C3-C10 alkyl group, in the presence of a catalyst system obtainable by contacting a metallocene compound of formula (I) Wherein M is an atom... Agent: Basell Usa Inc.

20080275255 - Stabilized borane-tetrahydrofuran complex: A stabilized borane-tetrahydrofuran complex is disclosed. Also disclosed are processes for the preparation of the borane-tetrahydrofuran complex and methods of storing and transporting the prepared complex. The borane-tetrahydrofuran complexes exhibit enhanced shelf life and increased self-accelerated decomposition temperatures.... Agent: Senniger Powers LLP (sgm)

20080275256 - Cyclopropanation process: s

20080275257 - Hydroxymethyl fluorescein derivatives for use as biological markers and dyes: Hydroxymethyl fluorescein derivatives are provided. The derivatives can be easily conjugated to other molecules, and are more permeable than other fluorescein derivatives. Methods of making the derivatives are also provided.... Agent: Meyer Unkovic & Scott LLP

20080275258 - Epigallocatechin dimers or trimers having lipase inhibitory activity and/or antioxidant activity: It is intended to provide a lipase activity inhibitor which shows a high inhibitory activity on pancreatic lipase, regulates the absorption of fat from meals and/or contributes to the regulation or prevention of obesity, a food and a drink containing the same, and a tea-origin lipase inhibitor being highly preferable... Agent: Drinker Biddle & Reath (dc)