Organic compounds -- part of the class 532-570 series inventions 11/08

20080293928 - Cytochrom p450 oxygenases: Nucleic acids encoding cytochrome P450 variants are provided. The cytochrome P450 variants of have a higher alkane-oxidation capability, alkene-oxidation capability, and/or a higher organic-solvent resistance than the corresponding wild-type or parent cytochrome P450 enzyme. A preferred wild-type cytochrome P450 is cytochrome P450 BM-3. Preferred cytochrome P450 variants include those having... Agent: Gavrilovich Dodd & Lindsey LLP Joseph R. Baker, Apc

20080293929 - Synthesis of sulfurized oligonucleotides: Methods for the formation of sulfurized oligonucleotides are provided. The methods allow for the formation of phosphorothioate linkages in the oligonucleotides or derivatives, without the need for complex solvent mixtures and repeated washing or solvent changes. Oligonucleotides having from about 8, and up to about 50, nucleotides can be sulfurized... Agent: Woodcock Washburn LLP

20080293930 - 3' end tagged oligonucleotides: The present invention provides compositions comprising oligonucleotides that have 3′ end groups (e.g. lipophilic moieties) that are useful in invasive cleavage reactions such as the INVADER assay. Specifically, the present invention provides compositions containing oligonucleotides with 3′ end groups configured for generating a detectable signal in invasive cleavages assays with... Agent: Medlen & Carroll, LLP

20080293931 - Methods and compositions for the removal of nucleic acid amplification inhibitors: An improved method for preparing nucleic acid extracts from environmental samples contaminated by polymerase inhibitors such as humic and fulvic acids is provided. The methods of the invention utilize chemical compositions capable of precipitating humic and/or fulvic acids from organic samples. The methods may be used in connection with the... Agent: Los Alamos National Security, LLC

20080287662 - Balanites aegyptiaca saponins and uses thereof: The invention relates to stable preparations of saponin nanovesicles, which can encapsulate active biological or chemical materials such as drugs, pesticides, vitamins, minerals and nutrients, and protect them. The preparations can be used, for example, in agricultural, pesticidal, dermatological and cosmetic compositions. The saponins per se can further be used... Agent: Browdy And Neimark, P.l.l.c. 624 Ninth Street, Nw

20080287663 - Process for production of 4-biphenylyazetidin-2-ones: The present invention relates to processes for the production of 4-biphenylylazetidin-2-one derivatives of formula... Agent: Heslin Rothenberg Farley & Mesiti PC

20080287665 - Canine igg nucleic acid molecules: The invention relates to canine immunoglobulin G (IgG) and canine interleukin-13 receptors (IL-13R) as well as fusion proteins containing canine IgG and/or canine IL-13R. In particular, the present invention discloses nucleic acid molecules encoding canine IgG, including species-specific regions of the heavy chain of canine IgG, and canine IL-13R alpha... Agent: Heska Corporation Legal Department

20080287664 - Hsp60 from arthrobacter: The hsp60 gene from a strain of Arthrobacter has been isolated and sequenced. The encoded protein is believed to be highly immunogenic, especially in fish, and also has utility as a non-specific adjuvant, and as an adjuvanting carrier for heterologous antigens.... Agent: Womble Carlyle Sandridge & Rice, PLLC

20080287666 - Detecting nucleic acid strands and inter-substance binding or interaction detecting method: Disclosed herein is a detecting nucleic acid strand including: a first nucleic acid strand having a first base sequence region capable of functioning as an aptamer, and a second nucleic acid strand having a second base sequence region, which is complementary to the first base sequence region and forms a... Agent: Bell, Boyd & Lloyd, LLP

20080287667 - Nucleic acid labeling compounds: Nucleic acid labeling compounds are disclosed. The compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofaranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.... Agent: Affymetrix, Inc Attn: ChiefIPCounsel, Legal Dept.

20080287668 - Nanostructures and methods of making: A nanostructure can include a first single-stranded nucleic acid, a plurality of complementary single-stranded helper nucleic acids hybridized with the first single-stranded nucleic acid, and at least one nanocube linked to a helper nucleic acid by a tether. The nanostructure can include at least two nanocubes each linked to a... Agent: Steptoe & Johnson LLP

20080287669 - Methods and compositions for identifying compounds useful in nucleic acid purification: The present invention provides methods, compositions, and kits for identifying compounds useful in nucleic acid purification. The methods of the invention include identifying certain characteristics of organic solvents such as miscibility in water, dielectric constant, and the class of the solvent.... Agent: Agilent Techologies Inc

20080287670 - Systems and methods for the purification of synthetic trityl-on oligonucleotides: Chromatographic loading solutions for use in the purification of trityl-on oligonucleotides. The solutions comprise an antichaotropic ion, a chaotropic ion, an alkaline salt, and a polar protic solvent, all at particular concentrations. The solution is useful in purifying oligodeoxyribonucleotides and oligoribonucleotides having either ACE or TBDMS protective caps. Also, methods... Agent: Stetina Brunda Garred & Brucker

20080287671 - Drug-eluting stents coated with p2y12 receptor antagonist compound: The present invention provides a P2Y12 receptor antagonist compound-eluting stent, wherein the stent is coated with one or more P2Y12 receptor antagonist compounds or a pharmaceutically acceptable salt, solvate, or hydrate thereof. When the stent is placed in a narrowed or damaged arterial vessel, a therapeutically effective amount of the... Agent: Howery LLP

20080287672 - Preserved compositions containing hyaluronic acid or a pharmaceutically-acceptable salt thereof and related methods: The invention provides a composition containing hyaluronic acid (HA) or a pharmaceutically-acceptable salt thereof preserved with a cationic preservative and related methods. In one embodiment, the pharmaceutically-acceptable salt is sodium hyaluronate. In another embodiment, the cationic preservative includes benzalkonium chloride (BAK).... Agent: Philip S. Johnson Johnson & Johnson

20080281087 - Method for bisulfite treatment: The present application is directed to a method for performing a bisulfite reaction to determine methylation positions in a nucleic acid, i.e. methylated and non-methylated cytosines. In this method, the nucleic acid is bisulfite treated and is bound to a solid phase when an alkaline solution is added for desulfonation... Agent: Roche Molecular Systems, Inc. Patent Law Department

20080281088 - Method and device for the isolation of nucleic acid from nucleic acid-comprising material: Method for the isolation of nucleic acid from nucleic acid comprising material, comprising the following steps: a) provision of a container suitable for the isolation of nucleic acid; b) introducing the nucleic acid comprising material and a desiccant into the container; c) drying the nucleic acid comprising material in the... Agent: Browdy And Neimark, P.l.l.c. 624 Ninth Street, Nw

20080281089 - Methods and systems for differential extraction: Methods are provided for differential extraction of DNA from at least two different cell types. Systems for carrying out the differential extraction methods are also provided. A kit is also provided for differential extraction of DNA from at least two different cell types using a multi-compartment container.... Agent: Mila Kasan, Patent Dept. Applied Biosystems

20080281090 - Microfluidic chemical reaction circuits: New microfluidic devices, useful for carrying out chemical reactions, are provided. The devices are adapted for on-chip solvent exchange, chemical processes requiring multiple chemical reactions, and rapid concentration of reagents.... Agent: Townsend And Townsend And Crew, LLP

20080275225 - Synthetic method of 20 (s)-ginsenoside rh2: A synthetic method of 20(s)-ginsenoside Rh2, that is 20(S)-protopanaxdiol-3-O-β-D-glucopyranoside, is comprised of: protecting protopanaxdiol (A1) selectively first to produce monosubstituted protopanaxdiol (A2); and Glycosidating the monosubstituted protopanaxdiol with Glucopyranosyl donor in the presence of Lewis acid catalyst; Deprotecting the product; Then separating and purifying to obtain 20(s)-ginsenoside Rh2. The method... Agent: Morrison & Foerster LLP

20080275226 - Medical use of paeoniflorin: The present invention provides the medical use of paeoniflorin in the manufacture of medicaments for treating and preventing apoplexy, Parkinson's diseases and other nervous system diseases.... Agent: Nixon & Vanderhye, PC

20080275227 - Process for modifying an organic natural substance by exchange reactions: A process for modifying an organic natural substance by exchange reactions is characterised in that the natural substance to be modified is heated in the liquid phase as an aerosol in a gas stream, with the exclusion of air, along a conveyance path and, after reaching a temperature dependent on... Agent: Collard & Roe, P.C.

20080275228 - Method and apparatus of automatically isolating and purifying nucleic acid: A method of automatically isolating and purifying nucleic acid from a nucleic acid-containing specimen is provided, the method comprising: injecting a liquid into a cartridge for isolation and purification of a nucleic acid including at least two openings from one opening of the at least two openings, in which the... Agent: Birch Stewart Kolasch & Birch

20080275229 - Method for increasing the speed of nucleic acid amplification reactions: The speed of a nucleic acid amplification reaction, such as the Polymerase Chain Reaction (PCR), can be increased by setting the temperature of heat sources above and below the desired denaturation, annealing, and extension temperatures. The reaction mixture is only contacted with the heat sources long enough for the desired... Agent: Pyle & Piontek Attn: Thomas R. Vigil

20080275230 - Polymers having covalently bound antibiotic agents: An antimicrobial composition comprising: a complex of a polysaccharide covalently bonded with an antibiotic. A medical device having an antimicrobial composition comprising: a complex of an oxidized regenerated cellulose covalently bonded with gentamicin.... Agent: Philip S. Johnson Johnson & Johnson

20080275231 - Method for preparing regenerated cellulose fiber by two-step coagulating bath process: The present invention relates to a non-toxic process and system for pilot-scale production of cellulose products, and particularly to a process and system for pilot-scale production of cellulose products by using aqueous sodium hydroxide/urea solution pre-colled to lower than −8° C., in which cellulose could dissolved rapidly. The said process... Agent: Workman Nydegger