Organic compounds -- part of the class 532-570 series inventions 08/08

20080207882 - Method for producing thiophene glycoside derivatives: The present invention relates to a process for preparing thiophene-glycoside derivatives of the general formula (I)... Agent: Andrea Q. Ryan Sanofi-aventis U.s. Llc

20080207885 - Method for site-specific labeling of rna using a deoxyribozyme: The present invention is a method for site-specific internal RNA modification. In accordance with the present method, a deoxyribozyme (DNA enzyme) is used as a catalyst to attach a tagging RNA to a pre-determined internal position of a target RNA molecule, wherein the tagging RNA is coupled to a label... Agent: Licata & Tyrrell P.c.

20080207883 - Platelet derived growth factor (pdgf) nucleic acid ligand complexes: This invention discloses a method for preparing a complex comprised of a PDGF Nucleic Acid Ligand and a Non-Immunogenic, High Molecular Weight Compound or Lipophilic Compound by identifying a PDGF Nucleic Acid Ligand by SELEX methodology and associating the PDGF Nucleic Acid Ligand with a Non-Immunogenic, High Molecular Weight Compound... Agent: Swanson & Bratschun, L.l.c.

20080207884 - Sirna targeting 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/imp cyclohydrolase (atic): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20080207886 - Mammalian cytokine-like polypeptide-10: A mammalian cytokine-like polypeptide, called Mammalian Cytokine-like polypeptide-10, (Zcyto10), polynucleotides encoding the same, antibodies which specifically bind to the polypeptide, and anti-idiotypic antibodies which bind to the antibodies. Zcyto10 is useful for promoting the healing of wounds and for stimulating the proliferation of platelets.... Agent: Zymogenetics, Inc. Intellectual Property Department

20080207887 - Phosphonylated fluorescent dyes and conjugates: Reagents are provided for the introduction of phosphonate groups into fluorescent dyes. Methods are also provided for preparing dye conjugates.... Agent: Townsend And Townsend And Crew, LLP

20080207888 - Methods of synthesizing and preserving a nucleotide-labeled microtubule: A method of synthesizing a nucleotide-labeled microtubule includes causing a microtubule which is stabilized after polymerization to react with a chemical crosslinking agent which has succinimide and maleimide and nucleotides which have a thiolated 3′ end or 5′ end to synthesize a microtubule-chemical crosslinking agent-nucleotide complex.... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.c.

20080207889 - Method for the isolation of nucleic acids: The present invention concerns an improved method for the isolation of nucleic acids such as DNA and RNA from bacterial, plant, animal or human cells as well as from cell cultures and virus cultures.... Agent: Womble Carlyle Sandridge & Rice, Pllc

20080207890 - Reagents for the improved synthesis of isoguanosine containing oligonucleotides: The present invention provides the combination of the O-2 diphenylcarbamoyl (“DPC”) and N-6 dimethy-laminomethylidene (“DMF”) protecting groups for isoguanosine nucleosides that can be utilized in oligonucleotide synthesis.... Agent: Foley & Lardner LLP

20080207891 - Methods for selective n-9 glycosylation of purines: A process for providing regiospecific and highly stereoselective synthesis of 9-β anomeric purine nucleoside analogs is described. The introduction of the sugar moiety on to 6-(azolyl)-substituted purine bases is performed so that highly stereoselective formation of the β anomers of only the 9 position regioisomers of the purine nucleoside analogs... Agent: Brinks Hofer Gilson & Lione/utah Utah Office

20080207892 - Nucleic acid amplification method using microchip and microchip, and nucleic acid amplification system using the same: A nucleic acid amplification method, includes: performing nucleic acid amplification using a microchip that comprises: a specimen introduction section; a reaction section; and a channel that connects the reaction section and the specimen introduction section, wherein the method further comprises preventing a reaction solution from evaporating during the amplification reaction,... Agent: Birch Stewart Kolasch & Birch

20080207893 - Process for grinding cellulose ether: The invention relates to a process for grinding cellulose ether comprising the steps of: a) grinding a cellulose ether comprising 20 to 90 wt % of water, based on the total weight of cellulose ether and water, and a cationic surfactant in a mill; and b) optionally drying the mixture... Agent: Akzo Nobel Inc.

20080207894 - Crosslinking reactions: The present invention relates to a process of making a starch crosslinked with sodium trimetaphosphate or with a combination of sodium trimetaphosphate and sodium tripolyphosphate. The reaction has increased efficiency over the standard crosslinking process and/or reduced phosphorus effluent.... Agent: National Starch And Chemical Company

20080207895 - Methods for synthesizing polysaccharides: This invention provides methods for the synthesis of HS polysaccharides or oligosaccharides. This invention provides HS polysaccharides and oligosaccharides thus obtained, and polysaccharides and oligosaccharides with anticoagulant activity.... Agent: Pearl Cohen Zedek Latzer, LLP

20080200659 - Combinatorial polyketide libraries produced using a modular pks gene cluster as scaffold: Combinatorial libraries of polyketides can be obtained by suitable manipulation of a host modular polyketide synthase gene cluster such as that which encodes the PKS for erythromycin. The combinatorial library is useful as a source of pharmaceutically active compounds. In addition, novel polyketides and antibiotics are prepared using this method.... Agent: Morrison & Foerster LLP

20080200661 - Composition for in vivo delivery: The present invention relates to the delivery of desired compounds (e.g., nucleic acids) into cells using releasable delivery systems which include complexing nucleic acids and delivery ligands.... Agent: Mirus Bio Corporation

20080200660 - Method for the hydrophobisation of dna molecules: The present invention relates to a method for the hydrophobisation of DNA molecules comprising mixing an aqueous solution of the DNA molecule with a solution of a cationic lipid or a surfactant in an organic solvent under agitation for a period in the range of 30 to 60 minutes to... Agent: Nixon & Vanderhye, PC

20080200662 - 9-fatty acid hydroperoxide lyase genes: A 9-fatty acid hydroperoxide lyase gene consisting of the nucleotide sequence as set forth in SEQ ID No: 1, and a 9-fatty acid hydroperoxide lyase gene consisting of the nucleotide sequence as set forth in SEQ ID No: 5.... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.C.

20080200663 - Novel lentiviral vectors for site-specific gene insertion: Murine leukemia virus (MLV) and lentivirus vectors have been used previously to deliver genes to hematopoietic stem cells (HSCs) in human gene therapy trials. However, these vectors integrate randomly into the host genome, leading to disruption or inactivation of vital host genes. The present invention discloses a novel lentiviral vector... Agent: Perkins Coie LLP

20080200664 - Cell regulatory genes, encoded products, and uses related thereto: This application describes the cloning of p63, a gene at chromosome 3q27-29, that bears homology to the tumor suppressor p53. The p63 gene encodes at least six different isotypes. p63 was detected in a variety of human and mouse tissue and demonstrates remarkably divergent activities, such as the ability to... Agent: Fish & Richardson PC

20080200665 - Nucleic acid molecules encoding proteins which impart the adhesion of neisseria cells to human cells: Described are nucleic acid molecules encoding proteins mediating the adhesion of bacteria of the genus Neisseria to human cells. Also described are the proteins encoded by these nucleic acid molecules and antibodies directed against them. Furthermore, pharmaceutical compositions, vaccines and diagnostic compositions containing the nucleic acid molecules, proteins and/or antibodies... Agent: Birch Stewart Kolasch & Birch

20080200666 - Production of glucosamine from plant species: The present invention relates to a process for generating glucosamine from plants wherein fresh plant materials, or re-hydrated dried plant materials or plant extracts, are heated at a temperature comprised between 70 and 110° C. for more than 10 hours, characterized in that a glucosamine precursor is added to said... Agent: Bell, Boyd & Lloyd LLP

20080200667 - Method for producing cellulose acylate film: Cellulose with a calcium (Ca) content of at most 10 ppm is used as a raw material of cellulose acylate. The cellulose acylate is synthesized by esterification of cellulose with carboxylic acid such as acetic acid. A dope containing the cellulose acylate and a solvent is continuously cast onto a... Agent: Sughrue Mion, PLLC

20080194801 - Robust multidentate ligands for diagnosis and anti-viral drugs for influenza and related viruses: Design and synthesis of a novel library of compounds comprising a spacer with an attachment element on one terminus and a recognition element on the other terminus is presented. The library of compounds can be attached to a solid support and used as an integral component of sensors and biosensors... Agent: Los Alamos National Security, Llc

20080194802 - Pharmaceutical dopamine glycoconjugate compositions and methods of their preparation and use: s

20080194803 - Cognitive performance with sirtuin activators: Provided herein are methods and compositions for enhancing the cognitive performance of a subject in need thereof. A method may include administering to a subject an agent that increases the level of protein or activity of a sirtuin, such as SIRT1.... Agent: Foley Hoag, LLP Patent Group (w/huv Hmv)

20080194804 - Method of nucleic acid hybridization: The present invention relates to a nucleic acid hybridization method and in particular to a method using a microfluidic chip-based hybridization device with modified procedures which shows the advantages of simplicity and efficiency. The method of the present invention is to mix the test nucleic acid and the probe nucleic... Agent: Rabin & Berdo, Pc

20080194805 - Method for the controlled oxidation of polysaccharides: The invention relates to a method for the controlled oxidation of oligo- and/or polysaccharides containing free —CH2OH primary hydroxyl groups, using an oxidising agent. The invention is characterised in that the oxidation reaction is performed in a densified fluid which is inert in relation to the oxidising agents employed. The... Agent: Nixon & Vanderhye, Pc

20080194806 - Use of lipid conjugates in the treatment of diseases: wherein L is a lipid or a phospholipid, Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol, Y is either nothing or a spacer group ranging in length from 2 to 30 atoms, X is a physiologically acceptable monomer, dimer, oligomer, or polymer, wherein X is a glycosaminoglycan; and... Agent: Pearl Cohen Zedek Latzer, LLP

20080194807 - Reformation of ionic liquids: Processes for recycling an ionic liquid comprising employing an initial ionic liquid as a solvent and/or reagent resulting in a modified ionic liquid and thereafter subjecting at least a portion of the modified ionic liquid to at least one anion exchange process to produce a reformed ionic liquid. The initial... Agent: Polly C. Owen

20080194808 - Cellulose esters and their production in carboxylated ionic liquids: Ionic liquids and cellulose ester compositions and processes and apparatus for producing ionic liquids and cellulose esters. Cellulose esters can be produced by dissolving cellulose in carboxylated ionic liquids and thereafter contacting the cellulose solution with at least one acylating reagent. Cellulose esters produced via the present invention can comprise... Agent: Polly C. Owen

20080194809 - Hydrophobic starch having near-neutral dry product ph: A free-flowing, hydrophobic starch composition has a near-neutral dry product pH. Methods for making the hydrophobic starch composition by preparing an aqueous mixture comprising a starch, a siliconate, and an acid, where the aqueous mixture has a near-neutral pH, and drying the starch solids to obtain a hydrophobic starch. Novel... Agent: Mcandrews Held & Malloy, Ltd

20080194810 - Method for purifying hyaluronic acid using calcium salt and phosphate salt, or calcium phosphate salt: The present invention relates to a method for purifying hyaluronic acid using calcium salt and phosphate salt, or calcium phosphate salt, specifically to a method for purifying hyaluronic acid characterized by effectively removing lipids, nucleic acids and proteins from an extract or a culture solution which contains hyaluronic acid by... Agent: Birch Stewart Kolasch & Birch

20080194811 - Catalysts and methods for complex carbohydrate hydrolysis: The present invention relates to methods and catalysts for hydrolyzing complex carbohydrates. In an embodiment, the invention includes a process for producing monosaccharides from a complex carbohydrate feedstock including the operations of heating the complex carbohydrate feedstock to a temperature greater than about 150 degrees Celsius and contacting the complex... Agent: Pauly, Devries Smith & Deffner, L.l.c.

20080188645 - Synthesis of nitrodibenzylfuran chromophore for photodeprotection of organic molecules: Inventors have developed a chromophore (nitrodibenzylfuranyl, or NBDF) for ultra efficient uncaging of a caged substrate (e.g., an organic molecule such as, for example, an amino acid, a biological molecules, such as, for example, second messengers inside cells). Photolysis of a NBDF derivative of EGTA (i.e. caged calcium) is about... Agent: Caesar, Rivise, Bernstein, Cohen & Pokotilow, Ltd.

20080188646 - 6r-(3,6-dideoxy-l-arabino-hexopyranosyloxy) heptanoic acid, preparation process for the same and dauer effect thereof: The present invention relates to a determination of a stereochemistry, a synthesis and dauer effect of 6R-(3,6-dideoxy-L-arabino-hexopyranosyloxy)heptanoic acid as a pheromone isolated from the Caenorhabditis elegance related to suppress of aging and stress. It becomes possible to develop medical substances using the pheromone relating to aging, stress, metabolism, signal transfer... Agent: Westman Champlin & Kelly, P.A.

20080188647 - Sirna targeting dna-damage-inducible transcript 4 (ddit4): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20080188648 - Sirna targeting human hairless protein (hr): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20080188649 - Method for producing glucosamine from microbial biomass: A more efficient method for producing glucosamine from microbial biomass such as, for example, fungal biomass is disclosed. In one embodiment, a method for obtaining glucosamine from fungal biomass includes providing fungal biomass containing chitin, such as Aspergillus, Penicillium, Mucor, or mushroom. The fungal biomass is then reacted in an... Agent: Marshall, Gerstein & Borun LLP

20080188650 - Method for affinity chromatography of antithrombin iii: m