Organic compounds -- part of the class 532-570 series inventions 07/08

20080182989 - Methods for oligomerizing olefins with chromium pyridine mono-oxazoline catalysts: The present invention provides a method of producing oligomers of olefins, comprising reacting olefins with a chromium based catalyst under oligomerization conditions. The catalyst can be the product of the combination of a chromium compound and a pyridyl mono-oxazoline compound. In particular embodiments, the catalyst compound can be used to... Agent: Exxonmobil Chemical Company

20080182990 - Process for the preparation of irinotecan hydrochloride trihydrate: The invention relates to an improved process for the preparation of Irinotecan hydrochloride trihydrate of formula (4) of enhanced yield, purity by contacting 1-chlorocarbonyl-4-piperidinopiperidine hydrochloride with 7-ethyl-10-hydroxy-camptothecin [IRT-3 (synthetic)] to obtain crude Irinotecan which is subsequently purified by solvent treatment, obtaining purified irinotecan which is converted into irinotecan hydrochloride trihydrate... Agent: Lowe Hauptman Ham & Berner, LLP

20080182991 - N- and o-substitued 4-[2-(diphenylmethoxy)-ethyl]-1-[(phenyl)methyl]piperidine analogs and methods of treating cns disorders therewith: N- and O-substituted 4[2-diaromaticmethoxy and methylamino)alkyl] piperidines exhibit high CNS activity with respect to the dopamine transporter (DAT) and serotonin transporter (SERT). Preferred compounds exhibit highly differential behavior as between the DAT and SERT and between the DAT and the norepinephrine transporter (NET). The compounds have utility in treating CNS... Agent: Brooks Kushman P.C.

20080177073 - Methods for preparing arene-bis (dicarboximide)-based semiconducting materials and related intermediates for preparing same: where Q, Ra, R1, W, and n are as defined herein. The present teachings also provide methods of preparing compounds of formulae I and II, including methods of preparing compounds of formula II from compounds of formula I. The compounds disclosed herein can be used to prepare semiconductor materials and... Agent: Kirkpatrick & Lockhart Preston Gates Ellis LLP (formerly Kirkpatrick & Lockhart Nicholson Graham)

20080177074 - Imiquimod production process: Provided is a process for producing highly pure 4-amino-1-isobutyl-1H-imidazo[4,5-c]quinoline (imiquimod), which includes reacting 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline with a non-gaseous amine precursor. Also provided are methods for isolating highly pure imiquimod. Further provided are intermediates useful in the production of imiquimod, methods for producing such intermediates, and methods for obtaining imiquimod from such... Agent: Leydig Voit & Mayer, Ltd

20080177075 - Compositions for progeny gender control: The present invention relates to the use of a zinc ion chelating agent for the manufacture of a composition for intra-vaginal administration for the control of egg fertilisation by sperm, for progeny gender determination and/or for reducing the incidence of defective progeny.... Agent: Ropes & Gray LLP

20080177076 - Processes for preparing substantially pure pantoprazole magnesium: Provided are processes for preparing substantially pure pantoprazole magnesium.... Agent: Kenyon & Kenyon LLP

20080177077 - Processes for the preparation of 3-(4-(2,4-difluorobenzyloxy)-3-bromo-6-methyl-2-oxopyridin-1(2h)-yl)-n,4-dimethylbenzamide: o

20080177078 - Conversion of 2-pyrazolines to pyrazoles using bromine: This invention relates to a method for preparing a compound of Formula 1 wherein L, R1, R2 and X are as defined in the disclosure, comprising contacting a 2 pyrazoline of Formula 2 with bromine at a temperature of at least about 80° C. (Formula 1) (Formula 2). This invention... Agent: Heiser, David E. E.i Du Pont De Nemours And Company

20080171881 - Method for producing organic compound and method for decomposing compound having dicarboximide skeleton: P

20080167467 - Substituted rylene derivatives: P

20080167468 - Silacycle compounds and methods of use thereof: The present invention relates to a diastereomeric mixture of Silacycle Compounds and methods for using the diastereomeric mixture of Silacycle Compounds for stereoselective synthesis.... Agent: Wilmerhale/columbia University

20080167469 - Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof: e

20080167470 - Process of enantiomeric resolution of d,l-(+_)-threo-methylphenidate: A process for preparing the d-threo isomer of methylphenidate hydrochloride which includes (i) resolving a racemic mixture of racemic threo-methylphenidate hydrochloride with a less than stoichiometric amount of tertiary amine base to obtain a methylphenidate-chiral acid salt, (ii) basifying the methylphenidate-chiral acid salt to obtain methylphenidate free base, and (iii)... Agent: Propat, L.L.C.

20080167471 - Processes for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives, polymorphs and pseudomorphs thereof: p

20080167472 - Tunable phenylacetylene hosts: Disclosed herein is a class of tunable phenylacetylene compounds as well as compositions and methods for their use as host compounds for ligand binding. In certain examples the hosts report binding events by exhibiting altered spectroscopic properties, such as different fluorescent emission spectra.... Agent: Klarquist Sparkman, LLP

20080167473 - Process for the preparation of optically active derivatives of 2-(2-pyridylmethylsulfinyl)-benzimidazole via inclusion complex with 1,1'-binaphthalene-2, 2'diol: Process for the preparation of optically active derivatives of 2-(2-piridylmethylsulfinyl)-benzimidazole, or salts thereof, by resolution of the corresponding racemic derivatives of 2-(2-piridylmethylsulfinyl)-benzimidazole. The resolution is performed through the formation of inclusion complexes with (S)-(−) or (R)-(+)-[1,1′-Binaphthalene]-2,2′-diol in the presence of an amine, followed by the break of the inclusion complex... Agent: Berenbaum, Weinshienk & Eason, P.c

20080167474 - Azulenyl nitrone spin trapping agents, methods of making and using same: The present invention provides azulenyl nitrones, such as those having the following general formula: (I) compositions comprising the same and methods of their use for the treatment or prevention of oxidative, ischemic, ischemia/reperfusion-related and chemokine-mediated conditions.... Agent: Marshall, Gerstein & Borun LLP

20080161567 - Metal complexes: The invention relates to novel metal complexes which can be used as functional materials in a series of different applications that can associated with the electronics industry in the broadest sense. The inventive compounds are described by formulas (1) and (1a).... Agent: Connolly Bove Lodge & Hutz, LLP

20080161568 - Phosphorescent iridium complex with non-conjugated cyclometalated ligands, synthetic method of preparing the same and phosphorescent organic light emitting diode thereof: The present invention discloses a phosphorescent tris-chelated transition metal complex comprising i) two identical non-conjugated cyclometalated ligands being incorporated into a coordination sphere thereof with a transition metal, and one ligated chromophore being incorporated into the coordination sphere; or ii) one non-conjugated cyclometalated ligand forming a coordination sphere thereof with... Agent: Bacon & Thomas, Pllc

20080161569 - Preparation of perylen-3,4:9,10-tetracarboxylic dianhydride and also of naphtalene-1,8-dicarboximides: hydrolyzing the diimide to the tetraalkali metal salt of perylene-3,4:9,10-tetracarboxylic acid in the presence of an inert organic solvent, of an alkali metal base and of water; and subjecting the tetraalkali metal salt of perylene-3,4:9,10-tetracarboxylic acid to the action of an aqueous inorganic acid to convert it into perylene-3,4:9,10-tetracarboxylic dianhydride;... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.c.

20080161570 - Processes for synthesizing quaternary 4,5-epoxy-morphinan analogs and isolating their n-stereoisomers: Methods for the synthesis of 4,5-epoxy-morphinaniums using dimethyl formamide and resolution of the diastereomeric products by means of HPLC.... Agent: Kelley Drye & Warren LLP

20080161572 - Preparation method: The present invention is directed to a novel method for the preparation of high purity irinotecan. This can be achieved by eliminating the excess of the other reagent, bipiperidinyl-1′-carbonyl chloride after it has reacted with 7-ethyl-10-hydroxy camptothecin and crystallizing the final product from a suitable solvent.... Agent: Birch Stewart Kolasch & Birch

20080161571 - Process for producing [1,4'] bipiperdinyl-1'-carbonyl chloride or hydrochloride thereof: The present invention is related to a process for the preparation of [1,4′]bipiperidinyl-1′-carbonyl chloride or its hydrochloride using methylene chloride as a solvent in the reaction of 4-piperidinopiperidine with phosgene and the removing the reaction solvent by using an additional distillation solvent to raise the distillation temperature.... Agent: Birch Stewart Kolasch & Birch

20080161573 - Process for the preparation of imiquimod and intermediates thereof: Novel intermediates useful for the preparation of Imiquimod and a process for the preparation of Imiquimod with the intermediates.... Agent: Young & Thompson

20080161574 - Diazafluorene compound: wherein R1 and R2 each represent a hydrogen atom, a substituted or unsubstituted alkyl group, or a substituted or unsubstituted aryl group, and may be the same or different from each other; and X1 and X2 each represent a halogen atom, and may be the same or different from each... Agent: Fitzpatrick Cella Harper & Scinto

20080161575 - Process for the synthesis of 6-amino-4-(3-chloro-4-fluorophenylamino)-7-ethoxyquinoline-3-carbonitrile: The present invention provides a process for the preparation of 6-amino-4-(3-chloro-4-fluoro-phenylamino)-7-ethoxy-quinoline-3-carbonitrile comprising the steps and products disclosed within this application.... Agent: Wyeth Patent Law Group

20080161576 - Method of forming a dry quaternary ammonium salt mixture: e

20080161577 - Substituted pyrrolidine and related compounds: wherein R1-R5 and a-e are as defined in the specification; or pharmaceutically-acceptable salt or solvate or stereoisomer thereof. The invention also directed to pharmaceutical compositions containing such compounds; processes and intermediates useful for preparing such compounds; and methods for treating disease conditions mediated by muscarinic receptors using such compounds.... Agent: Theravance, Inc.

20080161578 - Pim kinase inhibitors as cancer chemotherapeutics: Inhibitors of Pim kinases, ways to make them and methods of treating patients using them are disclosed.... Agent: Paul D. Yasger Abbott Laboratories

20080161579 - Process for synthesis of proton pump inhibitors: A process for preparation of rabeprazole sodium comprising oxidation of wet or dry rabeprazole sulphide with sodium hypohalite in water or a mixture of water and water miscible solvent using alkali metal hydroxide and catalyst is disclosed herein. The present invention also discloses process for preparation of rabeprazole sulphide.... Agent: Law Offices Of Albert Wai-kit Chan, Pllc