Organic compounds -- part of the class 532-570 series inventions 06/08

20080154039 - Process for making triphenylboron-pyridine compound: A process for improving the recovery of solid triphenylboron-pyridine compound (TPBP), while retaining desirable particle characteristics comprises the addition of an acid to neutralize at least a portion of the alkali contained in the aqueous mother liquor. By adjusting the pH of the product slurry to between about 8.5 and... Agent: Invista North America S.a.r.l.

20080154040 - Azafluorene derivative and organic light-emitting device using the derivative: A novel azafluorene derivative and an organic light-emitting device having the derivative are provided. The organic light-emitting device includes a pair of electrodes composed of an anode and a cathode one of which is a transparent or semi-transparent electrode, and an organic compound layer interposed between the pair of electrodes.... Agent: Fitzpatrick Cella Harper & Scinto

20080154041 - Synthesis of nicotine derivatives from nicotine: Methods of synthesizing nicotine analogs and derivatives are described. In some embodiments the methods utilize an alkyl or aryl silyl-substituted nicotine analog intermediate. Intermediates useful for the synthesis of nicotine and nicotine analogs are also described.... Agent: Myers Bigel Sibley & Sajovec

20080146801 - Method of processing substrate and chemical used in the same: A method of processing a substrate, including a step of processing an organic film pattern formed on a substrate, the step including, in sequence, a removal step of removing one of an alterated layer and a deposited layer formed on the organic film pattern, and a fusion/deformation step of fusing... Agent: Sughrue Mion, Pllc

20080146802 - Organic memory device using iridium organometallic compound and fabrication method thereof: Disclosed are a composition comprising a mixture of at least one iridium organometallic compound and an electrically conductive polymer, an organic active layer comprising the same, an organic memory device comprising the organic active layer and methods for fabricating the same. The organic memory device may include a first electrode,... Agent: Harness, Dickey & Pierce, P.L.C

20080146803 - Antibiotics containing borinic acid complexes and methods of use: The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by... Agent: Morgan, Lewis & Bockius LLP (sf)

20080146804 - Methods for making 3-o-protected morphinones and 3-o-protected morphinone dienol carboxylates: e

20080146805 - Process for the production of levorphanol and related compounds: A process for the production of morphinans with higher purity and yield, when compared to the conventional process, is described. Specifically, the process may be used to prepare levorphanol, levorphanol tartrate, and levorphanol tartrate dihydrate in high yields and substantially free from several process impurities.... Agent: Christy R Cooke Mallinckrodt Inc

20080146806 - Octahydropyrrolo[2,3c]pyridine derivatives and pharmaceutical use thereof: The present invention is related to octahydropyrrolo[2,3,c]pyridine derivatives of Formula (I) and use thereof in particular for the treatment and/or prophylaxis of autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, cancer, respiratory diseases and fibrosis, including multiple sclerosis, arthritis, emphysema, chronic obstructive pulmonary disease, liver and pulmonary fibrosis.... Agent: Oblon, Spivak, Mcclelland Maier & Neustadt, P.c.

20080146807 - Indazole-carboxamide compounds as 5-ht4 receptor agonists: The invention provides novel indazole-carboxamide 5-HT4 receptor agonist compounds. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat diseases associated with 5-HT4 receptor activity, and processes and intermediates useful for preparing such compounds.... Agent: Theravance, Inc.

20080146808 - Azabicyclo-octane inhibitors of iap: X1 and X2 are independently O or S; L is a bond or —C(X3)—, —C(X3)NR12, —C(X3)O— wherein X3 is O or S and R12 is H or R1; R1 is alkyl, a carbocycle, carbocycle-substituted alkyl, a heterocycle or heterocycle-substituted alkyl, wherein each is optionally substituted with halogen, hydroxyl, mercapto, carboxyl,... Agent: Genentech, Inc.

20080146809 - Process for the preparation of novel amorphous montelukast sodium: A process for the preparation of novel amorphous montelukast sodium by dissolving montelukast free acid in an organic solvent, converting into its alkali salt followed by vacuum drying or spray drying the solution. Alternatively by dissolution of montelukast sodium in organic solvent followed by vacuum drying or spray drying the... Agent: Lerner, David, Littenberg, Krumholz & Mentlik

20080146810 - Novel tricyclic compounds useful for the treatment of inflammatory and allergic disorders: process for their preparation and pharmaceutical compositions containing them: The present invention relates to novel tricyclic compounds useful for the treatment of inflammatory conditions, diseases of the central nervous and insulin resistant diabetes.... Agent: Darby & Darby P.c.

20080146811 - Compounds and methods for treatment of thrombosis: The invention provides compounds, pharmaceutical compositions, and methods for the treatment of thromboembolic disorders, such as, for example, arterial cardiovascular thromboembolic disorders, venous cardiovascular thromboembolic disorders, or thromboembolic disorders in the chambers of the heart.... Agent: Clark & Elbing LLP

20080146812 - Novel oxabispidine compounds and their use in the treatment of cardiac arrhythmias: There is provided compounds of formula I, wherein R1, R2, R4, R41 to R46, A, B and G have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.... Agent: Pepper Hamilton LLP

20080146813 - Facile synthesis of a series of liquid crystalline 2-(4'-alkylphenyl)-5-cyanopyridines: wherein Cn is a linear alkyl having 1-12 carbon atoms. The synthesis of the liquid crystalline 2-(4′-alkylphenyl)-5-cyanopyridine is completed in a two-step reaction. First, a Grignard reagent (such as 4-alkylphenylmagnesium bromide) is added to a 3-cyanopyridinium salt (such as N-phenyloxycarbonyl-3-cyanopyridinium chloride) to get a 1,2-dihydropyridine. Then the 1,2-dihydropyridine is oxidized... Agent: Pai Patent & Trademark Law Firm

20080139813 - Methods for preparing perylene/perinone pigments: A method for preparing a perylene pigment or perinone pigment involves a condensation reaction between perylene tetracarboxylic acid or naphthalene tetracarboxylic acid, or anhydrides or imides thereof, and amines in the presence of certain metal catalysts, such as ammonium molybdate, molybdenum oxide, and metal carbonyls, such as hexacarbonylmolybdenum, titanium carbonyl,... Agent: Dickstein Shapiro LLP

20080139814 - Process for preparing oxycodone having reduced levels of 14-hydroxycodeinone: The present invention is directed to processes for preparing oxycodone base and oxycodone hydrochloride compositions having less than 10 ppm of 14-hydroxycodeinone.... Agent: Philip S. Johnson Johnson & Johnson

20080139815 - Drug conjugates: e

20080139816 - Process for the production of cyclic diketones: The present invention relates to a process for the preparation of compounds of formula (I), wherein the substituents are as defined in claim 1, by reacting a compound of formula (II), with a bromine or chlorine source to form a compound of formula (III), wherein X is chlorine or bromine;... Agent: Syngenta Crop Protection , Inc. Patent And Trademark Department

20080139817 - Process for producing 2-(phenyl methyl thio)-3-pyridine carboxylic acid: The invention discloses an improved process for producing an intermediate to produce large quantity of 2-(Phenyl methyl thio)-3-pyridine carboxylic acid. The process comprises reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in presence of a base and an aprotic solvent. The resulting intermediate 2-(phenyl methyl thio)-3-cyanopyridine is hydrolyzed in presence of a base... Agent: Knobbe Martens Olson & Bear LLP

20080132701 - Light-emitting element and iridium complex: A light-emitting element having excellent light-emitting properties and with which it is possible to emit blue light at a high luminance for a long period of time, and an iridium complex for realizing the same. The light-emitting element has an external quantum efficiency of at least 5% and a light... Agent: Sughrue, Mion, Zinn, Macpeak & Seas, Pllc

20080132702 - Method of reducing alpha, beta unsaturated ketones in opioid compositions: The present invention is directed to a process for reducing the level of α, β-unsaturated ketone in an opioid analgesic composition by hydrogenation with diimide or a diimide progenitor.... Agent: Davidson, Davidson & Kappel, Llc

20080132703 - Process for reducing impurities in oxycodone base: The present invention is directed to a process for using n-butanol to prepare an oxycodone base compositions having reduced levels of impurities such as 14-hydroxycodeinone and DHDHC.... Agent: Philip S. Johnson Johnson & Johnson

20080132704 - 3-substituted quinuclidines and their use: Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases... Agent: Birch Stewart Kolasch & Birch

20080132705 - Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines: 2-Substituted-5-(1-alkylthio)alkylpyridines are produced efficiently and in high yield by cyclization and thioalkylation.... Agent: Dow Agrosciences Llc

20080132706 - Compounds as pde iv and tnf inhibitors: Compounds within the scope of the present invention also inhibit cyclic AMP phosphodiesterase, and are useful in treating a disease state associated with pathological conditions that are modulated by inhibiting cyclic AMP phosphodiesterase, such disease states including inflammatory and autoimmune diseases, in particular type IV cyclic AMP phosphodiesterase. The present... Agent: Andrea Q. Ryan Sanofi-aventis U.s. Llc

20080132707 - Solid states of pantoprazole sodium, processes for preparing them and processes for preparing known pantoprazole sodium hydrates: Crystalline pantoprazole sodium Forms II, IV, V, VI, VIII, IX, X, XI, XII, XIII, XIV, XV, XVI, XVII, XVIII, XIX and XX; pantoprazole sodium solvates containing water, acetone, butanol, methylethylketone, dimethylcarbonate, propanol and 2-methylpropanol; and amorphous pantoprazole sodium are disclosed.... Agent: Kenyon & Kenyon LLP