Organic compounds -- part of the class 532-570 series inventions 06/08

20080154026 - Water-treatment particle and a method of manufacturing thereof: A method of manufacturing water-treatment particles comprises respectively preparing a particle-fabricating solution that comprises chitinous composition and a forming solution first. Next, a complex solution is prepared by adding calcium sulfite into the particle-fabricating solution. Finally, the complex solution is pumped into the forming solution to form water-treatment particles. In... Agent: Knobbe Martens Olson & Bear LLP

20080154027 - Codon-optimized genes for the production of polyunsaturated fatty acids in oleaginous yeasts: The present invention relates to fatty acid desaturases and elongases able to catalyze the conversion of linoleic acid (LA) to γ-linolenic acid (GLA); α-linoleic acid (ALA) to stearidonic acid (STA); GLA to dihomo-γ-linoleic acid (DGLA); STA to eicosatetraenoic acid (ETA); DGLA to ETA; eicosapentaenoic acid (EPA) to docosapentaenoic acid (DPA);... Agent: E I Du Pont De Nemours And Company Legal Patent Records Center

20080154028 - Novel calcium-independent phospholipases a2, genes thereof and promoter of the same: Novel calcium-independent phospholipases A2; genes encoding the same; an antibody against them; an inherent promoter or a regulator gene which comprises a base sequence occurring in intron and inducing site-specific expression in response to an external stimulus; a method of expressing a target protein in response to an external stimulus;... Agent: Rader Fishman & Grauer Pllc

20080154029 - Process for manufacturing a composite sorbent material for chromatographical separation of biopolymers: The present invention relates to a sorbent material for separation and purification of biopolymers, particularly nucleic acids, having a solid support substantially modified with a copolymer coating comprising aromatic monomers and crosslinking compounds and unsaturated esters or ethers preferably attached to the support via a vinylchlorsilane. The use of these... Agent: Venable LLP

20080154030 - Method for increasing the solubility of betacyclodextrin: The solubility of betacyclodextrin in aqueous fluid is increased by combining niacin or niacinamide in the aqueous fluid with the betacyclodextrin.... Agent: Howard Eisenberg, Esq.

20080154031 - Method of preparing a separation matrix: The present invention relates to a method of preparing an insoluble separation matrix, which method comprises salt-treatment of a polysaccharide gel followed by cross-linking of the polysaccharide polymers. In one embodiment, the method comprises providing an aqueous solution of a gelatable native polysaccharide; lowering the temperature of the polysaccharide solution... Agent: Ge Healthcare Bio-sciences Corp. Patent Department

20080146787 - Thioether substituted aryl carbonate protecting groups: Embodiments of the invention include thioether substituted aryl carbonate protecting groups, and nucleoside monomers protected with thioether substituted aryl carbonate protecting groups. Aspects of the invention further included methods of synthesizing nucleic acids, e.g., oligonucleotides, using such protected nucleoside monomer monomers, as well as nucleic acids produced using methods of... Agent: Agilent Technologies Inc.

20080146788 - Positionally modified sirna constructs: The present invention provides oligomeric compounds having sufficient complementarity to hybridize to a nucleic acid target and methods for their use in modulating gene expression. In one embodiment the oligomeric compounds comprise double stranded constructs wherein one of the strands capable of hybridizing to a nucleic acid target, and has... Agent: Woodcock Washburn LLP

20080146789 - Methods for the separation of biological molecules using dioxolane: The present invention provides a method for the isolation of biological molecules by the adsorption of the molecules onto a mineral substrate in the presence of an appropriate mixture of salts and dioxolane. Preferably, the biological molecules are nucleic acids. Compositions and kits for performing the process according to the... Agent: Agilent Techologies Inc

20080146790 - Additive, method, and article for dna collection, stabilization, and purification: A system for collection, stabilization, and preparing total DNA for direct purification from biological samples is provided.... Agent: David W. Highet, Vp & Chief Ip Counsel Becton, Dickinson And Company

20080146791 - Microfluidic extraction method: The invention relates to an extraction method for isolating target molecules from a sample using a microfluidic carrier.... Agent: Rothwell, Figg, Ernst & Manbeck, P.c.

20080146792 - Starch esters, methods of making same, and articles made therefrom: Starch esters are made by: reacting a starch with an esterifying agent in the presence of a catalyst in a solvent for the starch ester, the esterifying agent including a mixture of at least two esterifying agents; or pre-treating a starch in a bath being free of an esterifying agent,... Agent: Hammer & Hanf, P.c.

20080146793 - Highly sulfated derivatives of k5 polysaccharide and their preparation: The purification of the E. coli K5 polysaccharide by treatment with isopropyl alcohol and elimination of lipophilic substances is described. The purified product can be used to prepare, after N-deacetylation, new N,O-sulfated polysaccharides with high degree of sulfation.... Agent: Nixon & Vanderhye, Pc

20080139796 - Method of manufacturing gel using polysaccharides as raw materials: After adding water to the carboxymethyl carrageenan which is raw material and mixing them well, the ionizing radiation of more than fixed dose is irradiated to the obtained paste sample of fixed concentration. As a result, an excellent hydrogel in heat resistance which does not dissolve at 50° C. or... Agent: Mattingly, Stanger, Malur & Brundidge, P.c.

20080139797 - Oligonucleotides containing high concentrations of guanine monomers: This invention pertains to methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers. In more detail, the invention relates to a method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or... Agent: John Petravich Integrated Dna Technologies, Inc.

20080139798 - Sirna targeting myeloid cell leukemia sequence 1: Efficient sequence specific gene silencing of myeloid cell leukemia sequence 1 is possible through the use of siRNA technology. By selecting particular siRNAs directed to myeloid cell leukemia sequence 1 by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing... Agent: Kalow & Springut LLP

20080139799 - Sirna targeting synuclein, alpha (snca-1): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20080139801 - Compositions, methods and kits for isolating nucleic acids from body fluids using anion exchange media: This invention provides compositions and methods for rapid separation, isolation and purification of nucleopolymers, especially nucleic acids, from biological samples using anionic exchange media. The method of the present invention can utilize commercially available strong or weak anion exchanger materials with selected solutions of known ionic strength for adsorption and... Agent: Mintz Levin Cohn Ferris Glovsky & Popeo Attn: Patent Intake Customer No. 35437

20080139800 - Process for the concentration and/or isolation of nucleic acid or nucleic acid-containing species: The present invention relates to a process for the concentration and/or isolation of nucleic acids or nucleic acid-containing species from a nucleic acid-containing solution, and a kit therefor. In one embodiment, the invention relates to the concentration and/or isolation of DNA and RNA from nucleic acid-containing solutions.... Agent: Seed Intellectual Property Law Group Pllc

20080139802 - Preparation of nucleosides ribofuranosyl pyrimidines: The present process provides an improved method for converting 2′-deoxy-2′-fluoro-2′-methyl-D-ribonolactones derivatives to 3-fluoro-3-methyl-2-chlorofuran compounds which are useful for the synthesis of nucleosides and improved processes for the synthesis of the D-ribonolactone compounds.... Agent: Roche Palo Alto Llc Patent Law Dept. M/s A2-250

20080139803 - Cellulose acylate film and method for saponification thereof: A cellulose acylate film, wherein at least one surface thereof has a contact angle of water of less than 55°, and wherein all or a part of hydroxyl groups of cellulose is substituted for an acyl group having 3 or more carbon atoms. The cellulose acylate film has an excellent... Agent: Buchanan, Ingersoll & Rooney Pc

20080132689 - Labile linkage for compound delivery to a cell: Described are ortho carboxy phenol derived acetals and compositions containing ortho carboxy phenol derived acetals which are useful for delivering biologically active compounds to cells. The acetals can be used to reversibly link up to three different molecules and have rapid hydrolysis kinetics in conditions which are present in a... Agent: Mirus Corporation

20080132690 - Corn event tc1507 and methods for detection thereof: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize TC1507 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and... Agent: Pioneer Hi-bred International, Inc.

20080132691 - Sirna targeting kinase insert domain receptor (kdr): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20080132692 - Photocleavable labeled nucleotides and nucleosides and methods for their use in dna sequencing: Provided are novel nucleotides, nucleoside, and their derivatives described herein, that can be used in DNA sequencing technology and other types of DNA analysis. In one embodiment, the nucleotide or nucleoside with an unprotected 3′-OH group is derivatized at the nucleobase to include a fluorescent dye attached via a linker... Agent: Fulbright & Jaworski, LLP

20080132693 - Bead emulsion nucleic acid amplification: Disclosed are methods for nucleic acid amplification wherein nucleic acid templates, beads, and amplification reaction solution are emulsified and the nucleic acid templates are amplified to provide clonal copies of the nucleic acid templates attached to the beads. Also disclosed are kits and apparatuses for performing the methods of the... Agent: Mintz Levin Cohn Ferris Glovsky & Popeo Attn: Patent Intake Customer No. 35437

20080132694 - Method for facilitating an automated isolation of a biopolymer using magnetic particles: The present invention provides a method for isolating biopolymers, particularly nucleic acids, such as DNA or RNA or hybrid molecules of DNA and RNA, from an aqueous solution utilizing magnetic particles, particularly silica magnetic particles. The method of the present invention involves forming a complex of the magnetic particles and... Agent: Mcdermott Will & Emery LLP

20080132695 - Cross-linked polysaccharide derivatives: The invention relates to substantially photochemically or thermally cross-linked polysaccharide derivatives in which the OH groups as OR groups have been esterified or converted into carbamate (urethane) or mixtures thereof and that do not contain photopolymerisable functional groups prior to the cross-linking. They can be used as carrier materials for... Agent: Paul Paglierani Novartis Institute For Biomedical Research, Inc.

20080132696 - Fractionation of charged polysaccharide: Polydisperse and charged polysaccharides are fractionated into low polydispersity fractions (preferably having pd <1.1), each containing species within a narrow range of molecular weights. An aqueous solution of the polydisperse polysaccharides is contacted with an ion exchange resin in a column and the polysaccharides are subjected to selective elution by... Agent: Morrison & Foerster LLP