Organic compounds -- part of the class 532-570 series inventions 05/08

20080125583 - Ribonucleic acid interference molecules: Ribonucleic acid interference molecules are provided. For example, in one aspect of the invention, at least one nucleic acid molecule comprising at least one of one or more precursor sequences having SEQ ID NO: 1 through SEQ ID NO: 103,948 and one or more mature sequences having SEQ ID NO:... Agent: Ryan, Mason & Lewis, LLP

20080125584 - Salts assisted selective extraction of 6-acetyl- 4,1' , 6' trichlorogalactosucrose and 4,1', 6' trichlorogalactosucrosse from aqueous reaction mixture: A process is described to increase efficiency of extraction of 4,1′,6′ trichlorogalactosucrose (TGS) from aqueous solution by addition of salt. The invention helps in reducing the quantity of solvent needed for achieving substantial extraction. The invention also leads to extraction of TGS substantially free from polar impurities.... Agent: Nath & Associates

20080119645 - Amidites and methods of rna synthesis: The present invention is directed to amidites useful in the synthesis of oligonucleotides comprising at least one RN moiety, and to methods of using such amidites in the synthesis of such oligonucleotides. The inventive amidites possess surprising coupling efficiency as compared to prior art amidites, while providing convenient intermediates in... Agent: Woodcock Washburn LLP

20080114161 - Modified probe molecules having self-complementary regions: The present invention concerns oligonucleotides containing one or more modified nucleotides which increase the binding affinity of the oligonucleotides to target nucleic acids having a complementary nucleotide base sequence. These modified oligonucleotides hybridize to the target sequence at a faster rate than unmodified oligonucleotides having an identical nucleotide base sequence.... Agent: Gen Probe Incorporated

20080114160 - Plant genome sequence and uses thereof: The present invention is in the field of plant biochemistry and genetics. More specifically the invention relates to nucleic acid molecules from plant cells, in particular, genomic DNA sequences from rice plants and nucleic acid molecules that contain markers, in particular, single nucleotide polymorphism (SNP) and repetitive element markers. In... Agent: Arnold & Porter, LLP

20080114162 - Functional and hyperfunctional sirna directed against bcl-2: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing Bcl-2.... Agent: Kalow & Springut LLP

20080114163 - Carbonylated compounds preparation process from a vegetable product and resulting carbonylated compounds: It is necessary to stabilize the resulting substituted aldehyde mixture with any suitable stabilizing agent for this purpose. Stabilizing agent proportion will vary from 0 to 5% in mass. A biocide is added in order to eliminate the possibility of bacterial degradation of any remaining non-reacted carbohydrates residual. This biocide... Agent: Ostrolenk Faber Gerb & Soffen

20080108800 - Selective reduction of spinosyn factors et-j and et-l to spinetoram: Spinetoram is selectively produced in excellent yields by hydrogenating a mixture of 3′-O-ethyl spinosyn J and 3′-O-ethyl spinosyn L in a water miscible organic solvent using hydrogen gas and a heterogeneous catalyst.... Agent: Dow Agrosciences Llc

20080108804 - Method for modifying rnas and preparing dnas from rnas: A method is disclosed for the modification of an end of RNA molecules and the use of such modified RNA molecules in cDNA synthesis for the purpose of cloning, detection, sequencing, and amplification of parts of the RNAs, the entire RNAs, or any cDNAs derived from such modified RNAs. The... Agent: Foley And Lardner LLP Suite 500

20080108805 - Method for the hybridisation of nucleic acids: m

20080108801 - Lipophilic conjugated irna agents: The invention relates to iRNA agents, which preferably include a monomer in which the ribose moiety has been replaced by a moiety other than ribose. The inclusion of such a monomer can allow for modulation of a property of the iRNA agent into which it is incorporated, e.g., by using... Agent: Lowrie, Lando & Anastasi, LLP A2038

20080108802 - Functional and hyperfunctional sirna directed against bcl-2: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing Bcl-2.... Agent: Kalow & Springut LLP

20080108803 - Functional and hyperfunctional sirna directed against bcl-2: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rationale design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing Bcl-2.... Agent: Kalow & Springut LLP

20080103295 - Process for the preparation of sucrose-6-ester by esterification in the presence of solid superacid catalyst: One embodiment of the present invention is a process of making sucrose-6-ester from sucrose by transesterification in the presence of a solid super acid catalyst such as SO42−—TiO2/Al2O3 or SO42−—TiO2. The sucrose-6-acetate is then chlorinated to afford sucralose-6-acetate, using BTC or thionyl chloride. Sucralose-6-acetate is converted into TPSGA for the... Agent: Perkins Coie LLP

20080103296 - Methods and apparati using single polymer analysis: The invention relates to methods for analyzing and characterizing single polymers such as nucleic acid molecules. In preferred embodiments, the single molecules are analyzed using single molecule detection and analysis systems.... Agent: Wolf Greenfield & Sacks, P.C.

20080103297 - Methods and devices for removal of organic molecules from biological mixtures using a hydrophilic solid support in a hydrophobic matrix: Methods and devices for removing small negatively charged molecules from a biological sample mixture that uses a solid-phase extraction material that includes a hydrophilic solid support at least partially embedded within a hydrophobic matrix.... Agent: 3m Innovative Properties Company

20080103298 - Process for the preparation of sucralose by the chlorination of sugar with triphosgene (btc): In one embodiment of the invention a method to prepare sucralose-6-acylate through chlorinating sucrose-6-acylater by BTC in the process of sucralose preparation is disclosed. In this embodiment a Vilsmeier reagent is firstly prepared below 0° C. by dissolving BTC in DMF or in component solvent, containing DMF, toluene, dichloroethane, chloroform... Agent: Perkins Coie LLP