Organic compounds -- part of the class 532-570 series inventions 02/08

20080051580 - Process to prepare camptothecin derivatives and novel intermediate and compounds thereof: New processes are disclosed for the preparation of camptothecin derivatives, such as, irinotecan and topotecan, as well as new intermediates and compositions thereof.... Agent: Klarquist Sparkman, LLP

20080051581 - Novel process for the manufacture of (+)-(s)-clopidogrel bisulfate form-1: The present invention relates to a novel process for the manufacture of blood-platelet aggregation inhibiting agent. In particular, the present invention is directed to a process for the manufacture of Methyl-(+)-(S)-α-(2-chlorophenyl)-6,7-dihydrothieno[3,2-c]pyridine-S-(4H)acetate bisulfate Form-I.... Agent: Bio Intellectual Property Services (bio Ips) LLC

20080051582 - Process for the preparation of tiotropium bromide: The invention is directed to improved processes for preparing Tiotropium bromide.... Agent: Lerner, David, Littenberg, Krumholz & Mentlik

20080045717 - Methods of making esters of camptothecins: Methods of preparing CPT-esters are described. The methods include using at least one acid in the esterification reactions or acylation reactions of camptothecins.... Agent: Kilyk & Bowersox, P.l.l.c.

20080045715 - Preparation of opiate analgesics by reductive alkylation: A process for preparing a compound of formula (A), (B) or (C): wherein P is H, CH3 or a hydroxyl protecting group; X is O, a protected ketone, OH, a protected hydroxyl group or H; Y is OH, a protected hydroxyl group or H; W is C(CH3)OH, C(CH3)(C(CH3)3)OH or COCH3;... Agent: Ratnerprestia

20080045716 - Process for the synthesis of morphinane compounds and intermediates thereof: This invention relates to intermediates useful in the preparation of opiate alkaloids, particularly morphinane compounds. The invention also relates to processes for preparing such intermediates and to processes which utilise such intermediates in the synthesis of morphinane compounds.... Agent: Ratnerprestia

20080045718 - Process and intermediates for the synthesis of 2-(quinolin-5-yl)-4,5 disubstituted-azole derivatives: This application discloses a novel process to synthesize 2-(Quinolin-5yo)-4,5-Disubstituted-Azole derivatives, which may be used, for example, as PDE IV inhibitor compounds in pharmaceutical preparations.... Agent: Schering-plough Corporation Patent Department (k-6-1, 1990)

20080039628 - Synthesis of solanum glycosides: The present invention relates to the chemical synthesis of solanum glycosides, in particular to the synthesis of solasonine as well as to novel β-monosaccharide intermediate compounds, of Formula (II), where each R1 is the same or different and independently represents a benzylidene, 4-nitrobenzylidene or 4-methoxybenzylidene group and each R2 is... Agent: Christensen, O'connor, Johnson, Kindness, PLLC

20080039629 - Benzothniazole compositions and their use as ubiquition ligation inhibitors: This invention describes compounds and pharmaceutical compositions useful as ubiquitin agent inhibitors. The compounds and pharmaceutical compositions of the invention are useful as inhibitors of the biochemical pathways of organisms in which ubiquitination is involved. The invention also comprises the use of the compounds and pharmaceutical compositions of the invention... Agent: Mcdonnell Boehnen Hulbert & Berghoff LLP

20080039630 - Cyanine compounds and their application as quenching compounds: Wherein the A moiety is a substituted pyridinium, unsubstituted pyridinium, substituted quinolinium, unsubstituted quinolinium, substituted benzazolium, unsubstituted benzazolium, substituted indolinium, or substituted indolinium. The invention further provides luminescent donor molecule-quencher pairs and luminescent donor molecule-quencher-luminescent acceptor molecule conjugates wherein the quencher is a cyanine compound of the present invention. The... Agent: Invitrogen Corporation C/o Intellevate

20080039631 - Process for preparing n-(substituted arylmethyl) -4-substituted-4-(disubstituted methyl) piperidines and intermediates: An improved process is described for preparing a N-(substituted arylmethyl)-4-substituted-4-(disubstituted methyl)piperidine of formula (I): wherein R1 and R2 are independently selected from the group consisting of halogen, CF3, OCF3, OCHF2, OCF2CHF2 and SF5; and Z and B are independently selected from the group consisting of CH and N; as well... Agent: Sterne, Kessler, Goldstein & Fox P.l.l.c.

20080039632 - Method of making cyanopyridines: Hydrolysis of cyanopyridine may be reduced by use of picoline as a predominately non-aqueous quench fluid. The picoline quench fluid may also be a reactant in the manufacture of cyanopyridine.... Agent: Baker & Daniels LLP

20080039633 - Process for preparing arylamines: d

20080033176 - Method for preparing prostaglandin derivative: (wherein Ph represents phenyl group, R1 represents a C1-7 alkyl group, a C1-7 alkenyl group, phenyl group, or benzyl group), which comprises the successive steps (1) to (8) described in the specification, or any one step or two or more successive steps selected from the group consisting of the steps... Agent: Greenblum & Bernstein, P.L.C

20080033177 - Process for the preparation of substituted-1,2,3,4-tetrahydroisoquinoline derivatives: The present invention is directed to a process for the synthesis of substituted-1,2,3,4-tetrahydroisoquinoline derivatives, useful as intermediates in the synthesis of pharmaceutical agents.... Agent: Philip S. Johnson Johnson & Johnson

20080033178 - Ionic liquids: Low melting ionic compounds of the general formula (cation) (R′SO4) in which R′ is a branched or linear, saturated or unsaturated, aliphatic or alicyclic functionalized or non-functionalized hydrocarbon chain with 3-36 carbon atoms are provided. These compounds can serve as ionic liquids, e.g. as solvents or solvent additives in chemical... Agent: Innovar, LLC

20080033179 - Optical recording material and optical recording medium: wherein rings A and B each represent a substituted or unsubstituted benzene or naphthalene ring; X represents O, S, Se, CR3R4 or NY; one of R1 and R2 represents a specific group of formula (II) or (III), with the other representing a C1 to C30 organic group; R3 and R4... Agent: Young & Thompson

20080033180 - Process for the preparation of 2-substituted-5-(1-alkylthio)alkylpyridines: 2-Substituted-5-(1-alkylthio)alkylpyridines are produced efficiently and in high yield from a non-pyridine source by cyclization.... Agent: Dow Agrosciences LLC