Organic compounds -- part of the class 532-570 series inventions 02/08

20080051571 - Silyl linker for solid-phase synthesis of nucleic acid: wherein each of R1 and R2 is an alkyl or aryl group, and (A) represents a spacer moiety; a 3′-end nucleoside unit having said compound linked via an oxygen atom to the 3-position of a sugar of the nucleoside or its derivative, a solid-phase support having the 3′-end nucleoside unit,... Agent: Birch Stewart Kolasch & Birch

20080051567 - Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect: e

20080051568 - Capture moieties for nucleic acids and uses thereof: A unimolecular probe for hybridization to a molecule comprising a target nucleic acid sequence, the probe includes: a first nucleic acid sequence complementary to the target sequence (target-binding sequence); and a second nucleic acid sequence complementary to a portion of the first nucleic acid sequence and capable of hybridization therewith... Agent: Goodwin Procter LLP Patent Administrator

20080051569 - Corn event tc1507 and methods for detection thereof: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize TC1507 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and... Agent: Pioneer Hi-bred International, Inc.

20080051570 - Stress-inducible plant promoters: The present invention discloses and claims stress-inducible plant promoters, DNA constructs with such promoters, transgenic plants containing such promoters and DNA constructs, isolated DNAs encoding such promoters, and methods of making and using such promoters, DNA constructs, transgenic plants, and isolated DNAs.... Agent: Sonnenschein Nath & Rosenthal LLP

20080051572 - Method for extracting nucleic acids: A device for extracting nucleic acids includes a cover including a first opening and a second opening spaced apart from the first opening, a chip including a first terminal to communicate with the first opening and a second terminal to communicate with the second opening, and a flow channel of... Agent: Akin Gump Strauss Hauer & Feld L.L.P.

20080051574 - Control of ph by direct addition of carbonates and bicarbonates during concentration of organics solvent extracts of 6-acetyl-4,1',6' trichlorogalactosucrose and 4,1',6' trichlorogalactosucrose: A novel process is described for control of pH where acid neutralizing agents, including carbonates and bicarbonates of metals and alkaline earth metals, are used in solid form in process of large scale manufacture of a chlorinated sucrose, particularly 4,1′, 6′ trichlorogalactosucrose (TGS) to neutralize acidity formed when ester group... Agent: Nath & Associates

20080051573 - Process for the production of sugar alcohols: Disclosed is a method for producing polyalcohols in the form of sugar alcohols from the group comprising sorbitol and mannitol and other optional C2 to C6 polyols. According to said method, a monosccharide, disaccharide, oligosaccharide, or polysaccharide containing at least one glucose unit and/or at least one fructose unit is... Agent: Patentanwaelte Lichti + Partner Gbr

20080045702 - Self-processing plants and plant parts: The invention provides polynucleotides, preferably synthetic polynucleotides, which encode processing enzymes that are optimized for expression in plants. The polynucleotides encode mesophilic, thermophilic, or hyperthermophilic processing enzymes, which are activated under suitable activating conditions to act upon the desired substrate. Also provided are “self-processing” transgenic plants, and plant parts, e.g.,... Agent: Syngenta Biotechnology, Inc. Patent Department

20080045703 - Sirna targeting platelet-derived growth factor receptor beta polypeptide (pdgfr): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20080039615 - Oxidation of carbohydrate with ultraviolet radiation: A process for the oxidation of carbohydrate with UV light. The process comprises the steps of providing a carbohydrate, combining the carbohydrate with an oxidant and exposing the combined carbohydrate and oxidant to ultraviolet light. The process occurs at alkaline conditions.... Agent: Norris Mclaughlin & Marcus, P.A.

20080039621 - Low-substituted hydroxypropylcellulose powder and method for producing the same: Provided are a low-substituted hydroxypropylcellulose powder having high compressibility, good flowability and excellent disintegration, and a method for producing the same. More specifically, provided is a method for producing a low-substituted hydroxypropylcellulose powder having a molar substitution number per anhydrous glucose unit of 0.05 to 1.0, which is insoluble in... Agent: Myers Bigel Sibley & Sajovec

20080039616 - Tandem affinity purification systems and methods utilizing such systems: The present invention generally relates to polypeptide tags and the purification of polypeptides, proteins, and protein fragments displaying such tags. More particularly, the invention is directed to novel polypeptides, nucleic acid sequences and vectors encoding novel polypeptides containing antigenic determinants. Also provided are methods and kits for using such polypeptides... Agent: Sigma-aldrich Co. Law Department

20080039617 - Sirna targeting neuropeptide y (npy): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20080039618 - Polycyclic sugar surrogate-containing oligomeric compounds and compositions for use in gene modulation: Compositions comprising first and second oligomers are provided wherein at least a portion of the first oligomer is capable of hybridizing with at least a portion of the second oligomer, at least a portion of the first oligomer is complementary to and capable of hybridizing to a selected target nucleic... Agent: Isis Pharmaceuticals Inc

20080039620 - 3'-end nucleoside unit comprising phosphoramidite: wherein (N) represents any nucleoside or its derivative, each of R1, R2, R4 and R5 is an alkyl or aryl group, R3 is a phosphate-protecting group, and n is an integer of from 1 to 5; a solid-phase support having said 3′-end nucleoside unit; and a method for the synthesis... Agent: Birch Stewart Kolasch & Birch

20080039619 - Apparatus and method for the more efficient isolation of nucleic acids: The present invention relates to an apparatus and a method for the more efficient cleaning of nucleic acids, and to a kit for carrying out this method.... Agent: Womble Carlyle Sandridge & Rice, PLLC Attn: Patent Docketing 32nd Floor

20080033154 - Process for producing 3-aminomethyltetrahydrofuran derivative: A 3-aminomethyltetrahydrofuran derivative is produced by preparing a 3-cyanotetrahydrofuran derivative in a high yield from a malic acid derivative, and reducing the cyano group of the 3-cyanotetrahydrofuran derivative. The process can produce the 3-cyanotetrahydrofuran derivative in a high yield from inexpensive industrial materials.... Agent: Buchanan, Ingersoll & Rooney PC

20080033155 - Processes for the production of aminoalkyl glucosaminide phosphate and disaccharide immunoeffectors, and intermediates therefor: This invention relates to processes for production of alkylamino glucosaminide phosphate compounds, and of disaccharide compounds, including various novel intermediates and intermediate processes. In one aspect, glycosyl halides are produced by reaction of an O-silyl glycoside with a dihalomethyl alkyl ether.... Agent: Townsend And Townsend And Crew, LLP

20080033156 - Polycationic compositions for cellular delivery of polynucleotides: The present invention relates to delivery of biologically active molecules to cells. Specifically, the invention relates to polycationic compositions, polymers and methods for delivering nucleic acids, polynucleotides, and oligonucleotides such RNA, DNA and analogs thereof, including short interfering RNA (siRNA), ribozymes, and antisense, or peptides, polypeptides, proteins, antibodies, hormones and... Agent: Mcdonnell Boehnen Hulbert & Berghoff LLP

20080033157 - Human anti-ngf neutralizing antibodies as selective ngf pathway inhibitors: This invention provides antibodies that interact with or bind to human nerve growth factor (NGF) and neutralize the function of NGF thereby. The invention also provides pharmaceutical compositions of said antibodies and methods for neutralizing NGF function, and particularly for treating NGF-related disorders (e.g., chronic pain) by administering a pharmaceutically... Agent: Mcdonnell Boehnen Hulbert & Berghoff LLP

20080033159 - Method for small volume nucleic acid synthesis: A method for synthesis of nucleic acids, with particular use for synthesis of cDNA. The method allows application of the cDNA to a microarray without the need for concentration or purification of the cDNA post-cDNA synthesis.... Agent: Law Office Of Morris E. Cohen

20080033158 - Multi layer chromatography of nucleic acids: Herein, we introduce three multimodal SPE methods using two to (n) purification columns to separate full length 5′-DMT-on oligonucleotides with size ranging from 40 to 180-mers from short length 5′-DMT-on oligonucleotides. Two of the said methods require using some columns sequentially with the collection and reprocessing of an intermediate fraction... Agent: Ctgen

20080033161 - Method for extracting nucleic acid: A method for extracting nucleic acid comprises: (a) putting a biological material in contact with a lysing solution to dissolve out nucleic acid; (b) adding a water-soluble organic solvent to an obtained solution of the dissolved nucleic acid, to prepare a lysate solution; (c) putting the lysate solution in contact... Agent: Birch Stewart Kolasch & Birch

20080033160 - Phenol-free method of isolating dna: A phenol-free method of isolating DNA from biological material includes contacting the biological material with a homogenization buffer, a first extraction buffer, and a second extraction buffer.... Agent: Tarolli, Sundheim, Covell & Tummino, LLP

20080033162 - Water-soluble cellulose derivative comprising a ligand: The invention relates to novel cellulose derivatives comprising a ligand capable of forming a complex with a polyvalent metal ion. The invention further pertains to a process of preparing such cellulose derivatives.... Agent: Akzo Nobel Inc.

20080033163 - Method for making derivatized guar gum and derivatized guar gum made thereby: A method for making a derivatized guar, comprising: (a) contacting derivatized guar splits, which have not been treated with a boron compound to crosslink the guar splits, with an aqueous wash medium comprising, based on 100 parts by weight of the aqueous wash medium: (i) from about 0.1 to about... Agent: Kevin E. Mcveigh Rhodia Inc.