Organic compounds -- part of the class 532-570 series inventions 12/07

20070299259 - Process for making solid triphenylboron-pyridine or its adduct: A process for producing solid triphenylboron-pyridine (TPBP) spherical particles by separately feeding into a vigorously agitated reaction zone (i) a stream of pyridine and a (ii) stream comprising a solution of sodium hydroxide adduct of triphenylboron (TPBA) whereby the total concentration of TPBA in the combined feed streams is in... Agent: Invista North America S.a.r.l.

20070299260 - Method for preparing hexahydro-8-hydroxy-2, 6-methano-2h-chinolizin-3 (4h) -one esters: The invention concerns a method for preparing optionally substituted 3-indolcarboxylic acid esters, with hexahydro-8-hydroxy-2,6-methano-2H-chinolizin-3(4H)-one. The invention is characterized in that the optionally substituted 3-indolcarboxylic acid is converted by means of a suitable halogenating agent, into corresponding acid halide, preferably corresponding acid chloride, and the latter is transformed with hexahydro-8-hydroxy-2,6-methano-2H-chinolizin-3(4H)-one. The... Agent: Hammer & Hanf, PC

20070299261 - Method for enantioselective preparation of sulphoxide derivatives: The present invention concerns enantioselective preparation of sulphoxide derivatives or their salts. The method consist in performing an enantioselective oxidation of a sulphur of general formula (I) A-CH2—SB, wherein: A is a diversely substituted pyridinyl ring and B is a heterocyclic radical comprising an imidazo-pyridinyl ring, using an oxidizing agent... Agent: Buchanan, Ingersoll & Rooney PC

20070299262 - Process for production of carbostyril compound: e

20070299263 - Hydroxy alkyl amines:

20070299264 - Method to control insects resistant to common insecticides: N-Substituted sulfoximines are effective at controlling insects resistant to common insecticides.... Agent: Dow Agrosciences LLC

20070293675 - Novel inhibitors of beta-lactamase: The intention relates to bacterial antibiotic resistance and, in particular, to compositions and methods for overcoming bacterial antibiotic resistance. The invention provides novel β-lactamase inhibitors, which are structurally unrelated to the natural product and semi-synthetic β-lactamase inhibitors presently available, and which do not require a β-lactam pharmacophore. The invention also... Agent: Mcdonnell Boehnen Hulbert & Berghoff LLP

20070293676 - Method for separation and purification of hydrocodone by preparative chromatography: A process for the purification of an impure preparation containing hydrocodone by means of a reverse phase preparative chromatography process is provided. In an illustrative embodiment a chromatographic column is loaded with a stationary phase, typically a silica particle having an organic ligand bound thereto. The impure preparation is acidified... Agent: Mallinckrodt Inc.

20070293677 - Process for the preparation of cabergoline: A process for preparing cabergoline (I) from ergoline-8β-carboxylic acid ester (XIII) comprising the following steps. (XIII), (XVI), (XVII), (XVIII), (XIX), (I). The present case also relates to the intermediates (XVI), (XVII), (XVIII) and (XIX) as well as the polymorphic amorphous form of Cabergoline (I) and the production thereof.... Agent: K.f. Ross P.C.

20070293678 - Process for the preparation of 6, 8-subs tituted '1, 7 naphthpyridin derivatives by reacting the 8-halo-'1, 7 naphthpyrid in-derivate with an organic boronic acid derivatives and intermadiates of this process: p

20070293679 - Diastereoselective addition of lithiated n-methylimidazole on sulfinimines:

20070293680 - Diastereoselective synthesis process with 6-bromo-4-(3-chlorophenyl)-2-methoxy-quinoline: A diastereoselective synthesis process for the preparation of (R)-(+)-6-[amino(4chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl]-4-(3-chlorophenyl)-1-methyl2(1H)-quinolinone which comprises the preparation of a compound of formula (XVII): and the stereochemically isomeric forms thereof wherein R is C1-6alkyl or C1-6alkylphenyl.... Agent: Philip S. Johnson Johnson & Johnson

20070293681 - Asymmetric imine hydrogenation processes: A process for the catalytic hydrogenation or asymmetric hydrogenation of imines of Formula (I) to the corresponding amines of Formula (II) is provided in which R1 is aryl; R2 is aryl, cyclic, alkyl, alkenyl or alkynyl; and R3 is alkyl. The catalytic system includes a ruthenium complex containing (1) a... Agent: Bereskin And Parr

20070293682 - Methods of preparing sulfinamides and sulfoxides: This invention encompasses novel methods of preparing sulfinamides and sulfoxides, particularly stereomerically pure sulfinamides and sulfoxides. The invention further encompasses novel compounds from which sulfinamides and sulfoxides can be prepared.... Agent: Martin A. Hay & Co.

20070293683 - N-phenyl-2-pyrimidine-amine derivatives: The present invention relates to novel amides and a process for preparing these amides.... Agent: Novartis Corporate Intellectual Property

20070287838 - Imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof as therapeutic compounds: The present invention pertains to certain imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof, which, inter alia, inhibit RAF (e.g., B-RAF) activity, inhibit cell proliferation, treat cancer, etc., and more particularly to compounds of the formula (I): wherein: J is independently —O— or —NRN1—; RN1, if present, is independently —H or... Agent: Nixon & Vanderhye, PC

20070287839 - Novel process for the preparation of esomeprazole and salts thereof: A novel process for the preparation of omeprazole and its enantiomers, such as esomeprazole, as well as the preparation of related 2-(2-pyridinylmethyl-sulphinyl)-1H-benzimidazoles, including pantoprazole, lansoprazole and rabeprazole, as recemates or single enantiomers, and their alkali or alkaline salts has been developed. The novel process involves the surprising discovery that protection... Agent: Ivor M. Hughes, Barrister & Solicitor, Patent & Trademark Agents

20070282106 - Efficient synthesis of 4,5-dihydro-pyrazolo[3,4-c]pyrid-2-ones: P

20070282107 - New process for preparing 4-aminomethyl-3-alkoxyiminopyrrolidine methanesulfonate: The present invention relates to a process for the preparation of 4-aminomethyl-3-alkoxyiminopyrrolidine methanesulfonate, a key intermediate of quinolone antibiotics. According to the process of the present invention, the total number of steps has been shortened to 2-3 steps, the solid separation is not required, and the use of costly chemicals,... Agent: Finnegan, Henderson, Farabow, Garrett & Dunner LLP

20070282108 - Process for producing carbostyril derivatives: The present invention provides a process for producing carbostyril derivatives (I) which are known to be useful as medical drug such as antithrombotic agent, cerebral circulation improver, anti-inflammatory agent, antiulcer agent, etc. in a high yield and a high purity. The carbostyril derivatives (I) can be produced by reacting a... Agent: Finnegan, Henderson, Farabow, Garrett & Dunner LLP

20070282109 - Process for the preparation of 17-0-vinyl-triflates as intermediates: A compound of formula (I) or a pharmaceutically-acceptable salt thereof, may be made by a process including a triflating step by which a ketone of formula (II) is converted into a triflate of formula (III) in the presence of a base comprising a tertiary or heterocyclic amine such that the... Agent: Nixon & Vanderhye, PC

20070282110 - Process for preparing diimine compounds: Process for preparing diimine compounds, in which a discarbonyl compound is reacted with primary amines in the presence of phosphorus pentoxide.... Agent: Basell Usa Inc.