Organic compounds -- part of the class 532-570 series inventions 11/07

20070276140 - Chiral 1,8-diarylnaphthalenes, methods of making them, and their use as sensors: One aspect of the invention relates to 1,8-diarylnaphthalene compounds. In certain embodiments, a compound of the invention is an N-oxide of a 1,8-diarylnaphthalene. In certain embodiments, the aryl group is an optionally substituted acridyl group. In certain embodiments, a compound of the invention is a single steroisomer. In certain embodiments,... Agent: Foley Hoag, LLP Patent Group, World Trade Center West

20070276141 - Preparation of pharmaceutical salts of [1,4] - bipiperidine: The invention provides anhydrous and hydrated forms of sodium salt of N-[[4-(3,4-dichlorophenoxy)[1,4′-bipiperidin]-1′-yl]carbonyl]-4-methyl-benzenesulfonamide and crystalline forms of N-[[4-(3,4-dichlorophenoxy)[1,4′-bipiperidin]-1′-yl]carbonyl]-4-methyl-benzenesulfonamide; and such compounds are modulators of chemokine (especially CCR3) activity and are especially useful for treating asthma and/or rhinitis.... Agent: Fish & Richardson P.C.

20070276142 - Catalytic asymmetric synthesis of optically active alpha-halo-carbonyl compounds: e

20070276143 - Method for producing optically active compound:

20070265448 - Ruthenium complex and process for producing tert-alkyl alcohol therewith: A tert-alkyl ketone, pinacolone was hydrogenated under pressurized hydrogen in the presence of a ruthenium complex (S)-1 and a base, and corresponding (S)-3,3,-dimethyl-2-butanol was thereby obtained in 100% yield and 97% ee.... Agent: Oliff & Berridge, PLC

20070265449 - Aryl or heteroaryl substituted 3,4-dihydroanthracene and aryl or heteroaryl substituted benzo[1,2-g]-chrom-3-ene, benzo[1,2-g]-thiochrom-3-ene and benzo [1,2-g]-1,2-dihydroquinoline derivatives having retinoid antagonist or retinoid inverse agonist type b: t

20070265450 - Novel processes for the preparation of (r)-alpha-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol: The present invention provides various processes for the preparation of (R)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol.... Agent: Andrea Q. Ryan Sanofi-aventis U.s. LLC

20070260064 - Synthesis of n-(4-fluorobenzyl)-n-(1-methylpiperidin-4-yl)-n'-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms: Disclosed herein are methods for synthesizing N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide. Also disclosed herein is the hemi-tartrate salt of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)-phenylmethyl)carbamide and methods for obtaining the salt. Further disclosed are various crystalline forms of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its hemi-tartrate salt including various polymorphs and solvates.... Agent: Knobbe Martens Olson & Bear LLP

20070260065 - Process for preparing amlodipine: A process for preparing phthalimidoamlodipine, which is useful as an intermediate for the preparation of amlodipine and its salts.... Agent: Dr. Reddy's Laboratories, Inc.

20070260066 - Process for the preparation of telithromycin: The present invention relates to the process for the preparation of compounds of formula (I) or its pharmaceutically acceptable salts Formula I The novel compounds (i) 10,11-Anhydro-2′,4″-di-O-benzoyl-12-O-imidazolylcarbonyl-6-O-methylerythromycin A of formula (Xa) Formula (Xa) (ii) 2′,4″-di-O-benzoyl-11-amino-11-N-[4-[4-(3-pyridyl)imidazol-1-yl]butyl]-11-deoxy-6-O-methylerythromycin A 11,12-cyclic carbamate of formula (XIa) Formula (XIa) (iii) 2′-O-benzoyl-11-amino-11-N-[4-[4-(3-pyridyl)imidazol-1-yl]butyl]-11-deoxy-5-O-desosaminyl-6-O-methylerythronolide A 11,12-cyclic carbamate of formula... Agent: Hamre, Schumann, Mueller & Larson, P.C.

20070260067 - Process for amination of acrylic macromonomers and products therefrom: Processes for forming adducts of amines with acrylic macromonomers are provided. Also provided are processes for using ring-closing reactions of the adducts to form lactams. The adducts are useful, for example, for making adhesives, surfactants, viscosity modifiers, processing aids, and other products.... Agent: E I Du Pont De Nemours And Company Legal Patent Records Center

20070260068 - Method for the preparation of crystal forms of torsemide in a pure state: A method for the preparation of crystal form 1 of polymorphous crystalline torsemide, wherein torsemide is dissolved in an ethanol-water mixture with heating, after which the torsemide is subsequently cooled and dried once crystal separation has been performed. Drying takes place in a blade drier, for example, with the crystals... Agent: Popovich, Wiles & O'connell, PA 650 Third Avenue South

20070255061 - 5-fluoro-, chloro-and cyano-pyridin-2-yl-tetrazoles as ligands of the metabotropic glutamate receptor-5: The present invention relates to new compounds of formula I, wherein Z, Q, X1, X2, R1 and R2, are as defined as in formula I, or salts, solvates or solvated salts thereof, processes for their preparation, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.... Agent: Birch, Stewart, Kolasch & Birch, LLP

20070255062 - Benzoyl amino pyridyl carboxylic acid derivatives useful as glucokinase (glk) activators: Compounds of Formula: (I); wherein: R1 is selected from: fluoro, chloro, C1-3alkyl and C1-3alkoxy; R2—X— is selected from: methyl, methoxymethyl and Formula: (X); n is 0,1 or 2; or a salt, pro-drug or solvate thereof are described. Their use as GLK activators, pharmaceutical compositions containing them, and processes for their... Agent: Morgan Lewis & Bockius LLP