Organic compounds -- part of the class 532-570 series inventions 09/07

20070225483 - Method for manufacture of carboxyalkylinulin: A method for the manufacture of carboxyalkylinulin is disclosed comprising preparing an aqueous medium containing dispersed therein a halogenoalkylcarboxylate, adding to the carboxylate containing medium, under substantially neutral pH conditions, an inulin followed by heating this mixture to a temperature in the range of from 60° C. to 90° C.... Agent: Armstrong Kratz Quintos Hanson & Brooks

20070225484 - Process for the isolation and stabilization of low-molecular weight aminoglycans from waste egg shells: (a) pre-preparation of the waste egg-shells for extraction of the embryonic low molecular weight aminoglycan compound of formula I using a polar organic solvent in water; (b) extraction of the low molecular weight aminoglycan compound of formula I as its soluble salt using an aqueous polar salt solution; (c) isolation... Agent: Bomi P. Framroze 3 Shree Sadan

20070225485 - Foldable polymers as probes: Disclosed herein are novel probes, which can be used to detect and identify target molecules of interest in a sample. The disclosed probes can be used to monitor conformational changes induced by molecular recognition events in addition to providing signaling the presence and/or identity of a target molecule. Methods, including... Agent: Klarquist Sparkman, LLP

20070225486 - Sirna targeting gremlin: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070225487 - Nucleic acid detection medium: An optimum reaction medium for performing nucleic acid detection and a method employing the medium are scribed.... Agent: Young & Thompson

20070225488 - Magnetic particles and methods of producing coated magnetic particles: An improved method for separating materials is provided, using colloidal, magnetizable aggregates, optionally silanized, and coated with a one or more layers of novel polysaccharide derivatives. Materials separated by the aggregates of the invention include inorganic and organic molecules, viruses, organelles, and cells. The invention also relates to a kit... Agent: James R. Abney

20070225489 - Method for modification of starch, starch and its use: The invention relates to a method for the modification of starch in such a way that it is suitable for surface sizing at high dry matter contents of >15%, typically >20%, even more than 25%. The modification of starch comprises at least degradation and stabilisation of the starch, whereby the... Agent: Joann Villamizar, Patent Department Ciba Specialty Chemicals Corporation

20070225490 - Cationic oligomer of a saccharide for resolving enantiomers and asymmetric synthesis: A cationic oligomer of a saccharide, wherein the saccharide is functionalized by a cationic group, for example an ammonium, phosphonium, imidazolium, or pyridinium group. In a preferred embodiment, the cationic oligomer of a saccharide is a cationic cyclodextrin. There is also provided a use of the cationic oligomer of a... Agent: Fish & Richardson, PC

20070219360 - Detection and modulation of iaps and naip for the diagnosis and treatment of proliferative disease: Disclosed are diagnostic and prognostic kits for the detection and treatment of proliferative diseases such as ovarian cancer, breast cancer, and lymphoma. Also disclosed are cancer therapeutics utilizing IAP antisense nucleic acids, IAP fragments, and antibodies which specifically bind IAP polypeptides.... Agent: Philip Swain, Phd C/o Gowling Lafleur Henderson

20070219363 - Chelating compound for drug delivery: Chelator containing compounds are utilized in the delivery of molecules and polymers to animal cells. At least one chelator such as crown ether is attached to a polymer and then associated with another polymer. An ion is then added to the mixture thereby forming condensed polymer. In condensed form and... Agent: Mirus Corporation

20070219359 - Gene encoding phosphoenolpyruvate synthase in plant protection: The present invention discloses a pathogenic gene derived from Xanthomonas campestris, a gene encoding phosphoenolpyruvate synthase. The gene encoding phosphoenolpyruvate synthase of this invention has one of the following nucleotide sequence: 1. a nucleotide sequence of SEQ ID NO:1; 2. a DNA sequence which has more than 80% homology with... Agent: Morrison & Foerster LLP

20070219362 - Sirna targeting azurocidin 1 (cartionic antimicrobial protein 37): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070219361 - Synthesis and compositions of nucleic acids comprising 2'-terminator nucleotides: The invention provides methods of producing blocked oligonucleotides that include 2′-terminator nucleotides. These blocked oligonucleotides are used primers and probes in a variety of nucleic acid technologies. Related kits are also provided.... Agent: Roche Molecular Systems Inc Patent Law Department

20070219364 - Methods and compositions for detecting targets: The present invention relates to methods and kits for detecting the presence or absence of (or quantitating) target nucleic acid sequences using ligation and amplification. The invention also relates to methods, reagents, and kits that employ addressable portions and labeled probes.... Agent: Mila Kasan, Patent Dept. Applied Biosystems

20070219365 - Enzymatic nucleic acid molecules: The present invention discloses nucleic acid enzymes and deoxyribonucleic acid enzymes capable of cleaving nucleic acid sequences or molecules, particularly RNA, in a site-specific manner, as well as compositions including same. Methods of making and using the disclosed enzymes and compositions are also disclosed.... Agent: The Scripps Research Institute

20070219367 - Parallel polymer sequencing methods: The present invention relates to a method of sequencing a target polynucleotide by enzymatic and/or chemical means. The sequencing method includes a method for characterizing multiple alleles in a sample, a method of calculating confidence levels in ascertained sequences, a method for comparing polynucleotide sequences, and a method of resolving... Agent: Saliwanchik Lloyd & Saliwanchik A Professional Association

20070219366 - Method and assembly for dna isolation with dry reagents: A DNA isolation method by removal of constituents, interfering with a subsequent PCR is disclosed. According to an embodiment of the method, all substances and method steps are fully integrated into a closed unit (cartridge) for single use, which allows entry of a DNA-containing sample and DNA-binding substrates are used... Agent: Harness, Dickey & Pierce, P.L.C

20070213522 - Oxidized microbial cellulose and use thereof: This application describes a bioresorbable biocellulose suitable for medical and surgical applications. In particular, the invention describes periodate oxidized microbial cellulose that can be produced to have any mechanical and degradation profile, depending on the desired application of the oxidized cellulose.... Agent: Foley And Lardner LLP Suite 500

20070213517 - Glycerol carbonate glycoside: i

20070213518 - Novel lipolytic enzyme lip2: The present invention provides a novel nucleic acid sequence, designated LIP2, encoding a lipolytic enzyme and the corresponding encoded amino acid sequences. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding at least one novel lipolytic enzyme, recombinant lipolytic enzyme proteins and methods for... Agent: Janet Kaiser Castaneda Genencor International Inc

20070213519 - Building block forming a c=c double bond upon reaction: A building block having the dual capabilities of transferring genetic information and functional entity precursor to a recipient reactive group is disclosed. The building block may be used in the generation of a single complex or libraries of different complexes, wherein the complex comprises an encoded molecule linked to an... Agent: Browdy And Neimark, P.l.l.c. 624 Ninth Street, Nw

20070213520 - Sirna targeting calcium/calmodulin dependent protein kinase iv (camk4): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070213521 - Sirna targeting cell division cycle 25 (cdc25c): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070213523 - Linker compound, ligand conjugate, and production methods thereof: where a, b, d, e are independently an integer of 0 to 6. X has a structure serving as a multi-branched structure moiety including three or more hydrocarbon derivative chains, wherein the hydrocarbon derivative chains each include an aromatic amino group at an end thereof, and may or may not... Agent: Morrison & Foerster LLP

20070208167 - Compounds and methods for modulating activation of nf-kappab: Compositions and methods for modulating the activation of nuclear factor κB (NF-κB) are provided. The compositions comprise one or more agents that modulate ubiquitination of phosphorylated IκBα and/or IκBβ. Such compositions may be used for treating diseases associated with NF-κB activation. Modulating agents include human E3 ubiquitin ligases, antibodies thereto... Agent: Jones Day

20070208168 - Insect inhibitory bacillus thuringiensis proteins, fusions, and methods of use therefor: Novel insect inhibitory proteins are disclosed comprising two different components, both of which are required for biological activity. Various methods of linking both components together, so that a single protein provides insect inhibitory activity, are disclosed. Also disclosed are novel Bacillus thuringiensis nucleic acid sequences encoding Coleopteran-inhibitory crystal proteins, designated... Agent: Howrey LLP

20070208169 - Detectable labeled nucleoside analogs and methods of use thereof: The invention relates to detectable labels useful for detection of nucleotide sequences. Specifically, the invention relates to labeled-imidazole-PEG compounds, such as nucleosides, nucleotides, and nucleic acids incorporating such compounds, and methods utilizing such compounds. The invention further relates to kits comprising labeled imidazole-PEG compounds.... Agent: Roche Molecular Systems Inc Patent Law Department

20070208170 - Intermediate and process for preparing of beta- anomer enriched 21-deoxy,21,21-difluoro-d-ribofuranosyl nucleosides: The present invention provides a highly stereoselective, simple and economical glycosylation process for preparation of β-anomer enriched 21-deoxy-21,21-D-ribofuranosyl difluoronucleosides of formula (II), and physiologically acceptable slats thereof, in particular, the β-enriched anomer of gemcitabine hydrochloride of formula (IIb) in purity of >99% is provided through utilization of a novel trichloroacetimidate... Agent: Schwegman, Lundberg, Woessner & Kluth, P.A.

20070208171 - Sugar donor: wherein X1 and X2 each independently represent a hydrogen atom or a hydroxyl-protecting group; Y represents a C7-20 aralkyl group which may optionally have one or more substituents selected from a halogen atom, a lower alkyl group or a lower alkoxy group; and Z represents a halogen atom, a C1-4... Agent: Greenblum & Bernstein, P.L.C