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Organic compounds -- part of the class 532-570 series August list RSS, inventions by patent category 08/07

20070203335 - Preparation of 6-carboxy-cellulose nitrates: The present invention relates to a new process for preparing 6-carboxy-cellulose nitrates and also to their use.... Agent: Connolly Bove Lodge & Hutz, LLP

20070203332 - Methods and compositions for targeted drug delivery: Disclosed are Drug Delivery Molecules (DDMs) which both facilitate functional imaging, as by PET, MRI or SPECT, and create a biological effect and methods of their use. These DDMs which are variously designed to target specific receptors, internalized and then function biologically, as for purposes of cell destruction or therapy.... Agent: Fitch Even Tabin And Flannery

20070203333 - Rna interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (sina): The present invention concerns methods and reagents useful in modulating vascular endothelial growth factor (VEGF, VEGF-A, VEGF-B, VEGF-C, VEGF-D) and/or vascular endothelial growth factor receptor (e.g., VEGFr1, VEGFr2 and/or VEGFr3) gene expression in a variety of applications, including use in therapeutic, diagnostic, target validation, and genomic discovery applications. Specifically, the... Agent: Mcdonnell, Boehnen, Hulbert And Berghoff, LLP

20070203334 - Process for preparing a synthetic intermediate for preparation of branched nucleosides: A process is provided for the preparation of a key intermediate in the preparation of 2′-branched nucleoside compounds. The process includes contacting a protected precursor 3,4-O-isopropylidene-2-C-substituted-D-arabinono-1,5-lactone with a fluorinating agent under anhydrous conditions and converting the precursor into a protected 2-deoxy-2-halo-2-C-disubstituted ribono-1,5-lactone and optionally into a 2-deoxy-2-halo-2-C-disubstituted ribono-1,4-lactone.... Agent: Jones Day

20070197779 - Bacterial cellulose-containing formulations: A new method to produce formulations of bacterial cellulose that exhibit improved viscosity-modifying properties particularly with low energy applied to effectuate viscosity changes therewith is provided. Such a method includes the novel co-precipitation with a water soluble co-agent that permits precipitation in the presence of excess alcohol to form an... Agent: Jane Shershenovich

20070197780 - Method and apparatus for dna purification: A method and apparatus for DNA purification are provided which use a silicone structure having a Sio2 layer formed on its surface. In the method, DNA is effectively purified from a fluid sample by maintaining the pH of the silicone structure's surface to be lower than the pKa of silanol... Agent: Cantor Colburn, LLP

20070191597 - Sialic acid derivatives for protein derivatisation and conjugation: Derivatives are synthesised of starting materials, usually polysaccharides, having sialic acid at the reducing terminal end, in which the reducing terminal unit is transformed into an aldehyde group. Where the polysaccharide has a sialic acid unit at the non-reducing end it may be passivated, for instance by converting into hydroxyl-substituted... Agent: Bromberg & Sunstein LLP

20070191598 - Process for preparing gemcitabine and associated intermediates: The present invention provides processes for preparing novel chemical substances that are useful as intermediates in the preparation of gemcitabine and processes for preparing gemcitabine therewith. Exemplary intermediates include mixtures of D-erythro and D-threo (3R- and 3S-) isomers of 3-(hydroxy)-2,2-difluoro-3-(2,2-dimethyldioxolan-4-yl)propionic acid salts. Also provided is a novel process for selectively... Agent: Leydig Voit & Mayer, Ltd

20070185322 - Methods of extracting rna: Methods and materials are disclosed for rapid and simple extraction and isolation of RNA from a biological sample involving the use of an acidic solution and a solid phase binding material that has the ability to liberate nucleic acids from biological samples, including whole blood, without first performing any preliminary... Agent: Richard Handley Lumigen, Inc.

20070185320 - Sirna targeting cell division cycle 20 homolog (cdc20): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070185318 - Sirna targeting connexin 43: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070185317 - Sirna targeting htra serine peptidase 1: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070185319 - Sirna targeting insulin-like growth factor 1 receptor (igf-1r): Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070185321 - Growth differentiation factor-8: Growth differentiation factor-8 (GDF-8) is disclosed along with its polynucleotide sequence and amino acid sequence. Also disclosed are diagnostic and therapeutic methods of using the GDF-8 polypeptide and polynucleotide sequences.... Agent: Lisa A. Haile, J.d., Ph.d. Dla Piper US LLP

20070179286 - Sirna targeting testis-specific serine kinase 4: Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed... Agent: Kalow & Springut LLP

20070179287 - Sequence-determined dna fragments encoding srf-type transcription factor proteins: The present invention provides DNA molecules that constitute fragments of the genome of a plant, and polypeptides encoded thereby. The DNA molecules are useful for specifying a gene product in cells, either as a promoter or as a protein coding sequence or as an UTR or as a 3′ termination... Agent: Fish & Richardson P.C.

20070179288 - Triphosphate oligonucleotide modification reagents and uses thereof: Hydrazino, oxyamino and carbonyl-based monomers and methods for incorporation into oligonucleotides during enzymatic synthesis are provided. Modified oligonucleotides are provided that incorporate the monomers provided herein. Immobilized oligonucleotides and oligonucleotide conjugates that contain covalent hydrazone or oxime linkages are provided. Methods for preparation of surface bound oligonucleotides are provided. Methods... Agent: David B. Waller David B. Waller & Associates

20070179289 - Compositions and methods for the use of fmoc derivatives in dna/rna synthesis: Methods of nucleic acid preparation are described, including preparation of mRNA, using FMOC derivatives to synthesize oligonucleotides in addition to applying FMOC protocols to various therapeutic and diagnostic methods. In some embodiments a single stranded oligonucleotide is synthesized bound to a polymer support (such as optic fiber glass filters) using... Agent: Perkins Coie LLP

20070179290 - Production method of fluorinated purine nucleoside derivative, intermediate therefor and production method thereof: t

20070179291 - Starch network as absorbent or superabsorbent materials and their preparation by extrusion: The present invention relates an absorbent material consisting of a molecular network of starch molecules, the starch molecules comprising an amylopectin content of at least 90% (w/w). The molecular network can either be comprised of self-entangled starches or cross-linked starches.... Agent: Fulbright & Jaworski L.L.P.

20070179292 - Production of low molecular weight ethylcellulose: Ethylcellulose having an ethoxyl content of from 40 to 55 percent and a viscosity of from 1 to 100 mPa's, measured as a 5 weight percent solution in toluene and ethanol at a volume ratio of 80:20 at 25° C., is produced by depolymerization of an ethylcellulose having an ethoxyl... Agent: The Dow Chemical Company