Organic compounds -- part of the class 532-570 series inventions 06/07

20070149783 - Process for preparing topotecan: A process for preparing topotecan.... Agent: Dr. Reddy's Laboratories, Inc.

20070142636 - Process for preparing bisphosphonic acids: A process for preparing a bisphosphonate compound comprises reacting a carboxylic acid with a phosphonating agent, in a cresol solvent.... Agent: Dr. Reddy's Laboratories, Inc.

20070142637 - Process for the preparation of crystalline polymorph of a platelet aggregation inhibitor drug: The present invention relates to a new method of preparation of the polymorph form 1 of methyl (S)-(+)-(2-chlorophenyl)-2-(6,7-dihydro4H-thieno[3,2-c]pyridine-5-yl-acetate hydrogensulfate of the formula (I).... Agent: Birch Stewart Kolasch & Birch

20070142638 - Ornithine derivatives as prostaglandin e2 agonists or antagonists: Ornithine derivatives of the formula (I): wherein X is —CO— or —(CH2)k— (wherein k is 1, 2 or 3); Y is Z-(CH2)n—, and the like; {wherein Z is R1—CO—NR4—, and the like, (wherein R1 is aryl, and the like; and R4 is hydrogen, or lower alkyl); and n is 1,... Agent: Oblon, Spivak, Mcclelland, Maier & Neustadt, P.C.

20070142639 - Process for production of amines: wherein A1 represents a spacer; X1 and X2 represent each independently a divalent nonmetal atom or a divalent nonmetal atomic group; and Y1 is oxygen or sulfur. The invention provides a process by which amines (particularly optically active amines) useful as intermediates of medicines, agricultural chemicals, or the like can... Agent: Wenderoth, Lind & Ponack, L.L.P.

20070142640 - Method for producing 1, 2-dihydropyridine-2-one compound: e

20070142641 - Atazanavir conjugates and antibodies useful in immunoassay: Activated haptens useful for generating immunogens to the HIV protease inhibitor atazanavir, immunogens useful for producing antibodies to atazanavir, and antibodies and labeled conjugates useful in immunoassays for determination of atazanavir. The haptens feature an activated functionality at the central, non-terminal hydroxyl group.... Agent: Roche Diagnostics Operations Inc.

20070142642 - Method for the production of compounds with quaternary sp2-hybridised nitrogen atoms: Process for preparing ionic compounds comprising cations containing quaternary sp2-hybridized nitrogen atoms, which comprises reacting compounds containing a double-bonded nitrogen atom with a dialkyl sulfate with participation of both alkyl groups of the dialkyl sulfate and, if appropriate, subjecting the resulting ionic compound containing sulfate anions to an anion exchange.... Agent: Connolly Bove Lodge & Hutz, LLP

20070135638 - Process for the manufacture of lysergic acid: Lysergic acid is formed in high yields and high quality by isomerizing paspalic acid in a phase separated mixture formed by paspalic acid and a concentrated aqueous metal hydroxide solution.... Agent: Lerner, David, Littenberg, Krumholz & Mentlik

20070135639 - Benzimidazolone compound: s

20070135640 - Process for preparing imiquimod: The present invention provides a process for preparing 4-amino-1-isobutyl-1H-imidazo[4,5-c]quinoline (Imiquimod) of formula (I). The process comprises heating 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline of formula (II) with formamide, and optionally with bubbling of gaseous ammonia to afford Imiquimod of formula (I). According to the present invention, by using this process and novel purification methods, essentially... Agent: Martin Moynihan Prtsi, Inc.

20070135641 - Synthesis: The present invention provides an improved process for the production of [(±)-endo]-4-amino-5-chloro-2-methoxy-N-(1-azabicyclo[3.3.1 ]non-4-yl)benzamide hydrochloride, compositions thereof, and intermediates thereto.... Agent: Choate, Hall & Stewart LLP

20070135642 - Process for making montelukast and intermediates therefor: e

20070135643 - Process for making montelukast and intermediates therefor:

20070135644 - Process for making donepezil: A process for making donepezil using a new intermediate salt of formula (VIIIa), especially the tosylate, can achieve good yields.... Agent: SynthonIPInc

20070135645 - Process for the preparation of guanidinium salts: The present invention relates to a two-step process for the preparation of guanidinium salts of the formula (1), where the substituents R have a meaning indicated in claim, and A− is a sulfonate, alkyl- or arylsulfate, hydrogensulfate, imide, methanide, carboxylate, phosphate, phosphinate, phosphonate, borate, thiocyanate, perchlorate, fluorosilicate or nitrate, and... Agent: Millen, White, Zelano & Branigan, P.C.

20070129548 - Polymorphs of an androgen receptor modulator: Compounds of structural formula I are modulators of the androgen receptor (AR) in a tissue selective manner. These compounds are useful in the enhancement of weakened muscle tone and the treatment of conditions caused by androgen deficiency or which can be ameliorated by androgen administration, including osteoporosis, osteopenia, glucocorticoid-induced osteoporosis,... Agent: Merck And Co., Inc

20070129549 - Stable lamotrigine pharmaceutical compositions and processes for their preparation: The invention relates to processes for the preparation of piperidylmethyl-indanones, and to the use of these compounds as intermediates for the preparation of benzyl-piperidylmethyl-indanones which are active compounds for the treatment of CNS disorders. The invention also relates to a process for the preparation of donepezil or a pharmaceutically acceptable... Agent: Ranbaxy Inc.

20070129550 - Amino acids with affinity for the alpha-2-delta-protein: Certain β-amino acids that bind to the alpha-2-delta (α2δ) subunit of a calcium channel are disclosed. These compounds and their pharmaceutically acceptable salts are useful in the treatment of a variety of psychiatric, pain and other disorders. Also disclosed are methods of making the β-amino acids.... Agent: Warner-lambert Company

20070129551 - Method for making nicotine hapten: r