Organic compounds -- part of the class 532-570 series inventions 05/07

20070123707 - Nitrogen-containing monodentate phosphines and their use in catalysis: The present invention relates to novel nitrogen—containing monodentate phosphane ligands of formula (I) and to their use in catalytic reactions, especially in the improvement of haloaromatic compounds.... Agent: Oblon, Spivak, Mcclelland, Maier & Neustadt, P.C.

20070123708 - Process for the synthesis of quinoline derivatives: The present invention provides an improved process for the synthesis of quinoline derivatives. More particularly the present invention provides an improved and economical process for the synthesis of quinoline derivatives by the reaction of aniline/substituted anilines using two different catalysts, ferric chloride and zinc chloride in a one-pot set up... Agent: Reed Smith LLP

20070123709 - Beta-amino acids: Disclosed are β-amino acid monomers containing cylcoalkyl, cycloalkenyl, and heterocylic substituents which encompass the α and β carbons of the peptide backbone and β-polypeptides made from such monomers. Method of generating combinatorial libraries of polypeptides containing the β-peptide residues and libraries formed thereby are disclosed.... Agent: Dewitt Ross & Stevens S.c. Wisconsin Alumni Research Foundation

20070123710 - Industrial method for seperation and purification of fentanyl by reverse phase preparative chromatography: There is described a process for the purification of an impure preparation containing fentanyl by means of a reverse phase preparative chromatography process. A chromatographic column is loaded with a stationary phase, typically a silica particle having an organic ligand bound thereto. With a loading ratio of from about 50... Agent: Jeffrey S Boone Mallinckrodt Inc

20070117981 - Rhodium quinonoid catalysts: In accordance with one aspect of the invention a rhodium quinonoid catalyst is disclosed.... Agent: Harrington & Smith, PC

20070117982 - Method for producing 1,2-unsaturated azasteroids: The invention relates to a method for producing 1,2-unsaturated azasteroids of general formula (I), from a structurally related, saturated azasteroid of general formula (II).... Agent: Lerner Greenberg Stemer LLP

20070117983 - Sensitive and selective method and device for the detection of trace amounts of a substance: A piezoelectric crystal element and a sensor utilizing the same are presented for use in a sensor device for identifying at least one foreign material from environment. The crystal element comprises at least one crystal resonator in the form of a inverted mesa structure, which has a membrane-like region and... Agent: Greer, Burns & Crain

20070117984 - Process for preparing cyanopyridines and suitable catalysts therefor: The invention relates to a method for the manufacture of cyanopyridines from methylpyridines by their conversion with ammonia and oxygen and catalysts suitable therefor which contain further transition metals in addition to vanadium and phosphorus.... Agent: Ice Miller LLP

20070112195 - Regioselective halogenation of nicotine and substituted nicotines: P

20070112196 - New coupling agents for peptide synthesis: The present invention is directed to compounds of the formula (I) and (II) or salts thereof or N-oxides and their use in peptide synthesis.... Agent: Reinhart Boerner Van Deuren S.c. Attn: Linda Kasulke, Docket Coordinator

20070112197 - Process for the preparation of alkyl-and aryl-diphosphonic acids and salts thereof: The invention relates to a process for the preparation of diphosphonic acids by reaction of a carboxylic acid with a mixture of phosphorous acid and phosphorus oxychloride in defined molar ratios and in the absence of solvents. The invention futher relates to ibandronic acid monosodium salt in the amorphous form.... Agent: Ostrolenk Faber Gerb & Soffen

20070112198 - Method for manufacture of thip: The present invention relates to a new method of preparing gaboxadol (THIP), which is useful for treating sleep disorders. In particular a method of preparing THIP comprising reacting a compound of formula (8b) or a salt thereof with an acid, typically a mineral acid, to obtain THIP as an acid... Agent: Darby & Darby P.C.

20070112199 - Asymmetric aldol additions using bifunctional cinchona-alkaloid-based catalysts: One aspect of the present invention relates to asymmetric catalytic nitroaldol (Henry) reactions with ketones as the electrophilic component. In one embodiment, the present invention relates to asymmetric nitroaldol reactions with α-keto esters catalyzed by a new C6′-OH cinchona alkaloid catalyst. In certain embodiments, this reaction is operationally simple and... Agent: Foley Hoag, LLP Patent Group, World Trade Center West

20070112200 - Non-racemic hexafluoreleucine,and methods of making and using it: One aspect of the invention relates to hexafluoroleucine and congeners thereof, and methods of making the compounds. Another aspect of the invention relates to the synthesis of protein cores comprising hexafluoroleucine and congeners thereof. Certain peptides comprising hexafluoroleucine and congeners thereof have been characterized using comparative biophysical studies. In general,... Agent: Foley Hoag, LLP Patent Group, World Trade Center West

20070106077 - Synthesis of substituted heterocyclic compounds: The invention relates to a method of synthesizing heterocyclic compounds. The invention is characterised in that it consists in opening a compound having formula (I), wherein: —X represents NH, O, S or a N-p group, p being a protective group, such as Boc or Troc; —Y represents N, O, S;... Agent: Nixon & Vanderhye, PC

20070106078 - Process for the preparation of fexofenadine: The invention relates to highly pure fexofenadine and a process for preparing highly pure fexofenadine. The invention also relates to pharmaceutical compositions that include the highly pure fexofenadine and use of said compositions for treating a patient for allergic reactions.... Agent: Ranbaxy Inc.

20070100145 - Titanium substituted pyridyl amine complexes, catalysts and processes for polymerizing ethylene and stryene: New compositions, titanium-ligand complexes and arrays with pyridyl-amine ligands are disclosed that catalyze the polymerization of monomers into polymers. These catalysts with titanium metal centers have high performance characteristics, including high styrene incorporation into ethylene/styrene copolymers.... Agent: Symyx Technologies Inc Legal Department

20070100146 - Process for the preparation of imidazo[4,5-c]-quinolin-4-amines: wherein R is hydrogen, C1 to C6 alkyl, C1 to C6 alkoxy or halo, R1 and R2 are independently hydrogen, C1 to C10 alkyl, C1 to C10 alkoxy, C3 to C10 cycloalkyl, C3 to C10 alkenyl, C5 to C10 cycloalkenyl, C2 to C10 alkynyl, C6 to C20 aryl or substituted... Agent: Richard J. Hammond, Ph.d.

20070100147 - Process for preparing raloxifene hydrochloride: Process for preparing raloxifene hydrochloride with a purity greater than 98% and low aluminium content comprising the following stages a) demethylation of 6-methoxy-2-(4-methoxyphenyl)benzo[b]thiophene in pyridine and hydrochloric acid to obtain 6-hydroxy2-(4-hydroxyphenyl)benzo[b]thiophene in pyridine hydrochloride, b) acetylation of 6-hydroxy-2-(4hydroxyphonyl)benzo[b]thiophene with an acetylating agent to obtain the corresponding 6-acetoxy-2-(4 acetoxyphenyl)benzo[b]thiophene, c) acylation... Agent: Jay S Cinamon Abelman Frayne & Schwab