Organic compounds -- part of the class 532-570 series inventions 10/06

20060241299 - Process for making spirolactone compounds: This invention relates to a process for making spirolactone compounds of general formula I, having an improved IA/IB ratio, according to the following shceme....

20060241300 - Phosphazenium salt mixtures containing hexakis(amino)diphosphazenium, tetrakis(amino)-phosphonium and polyaminophosphazenium salts: The invention relates to mixtures containing 5 to 99.5 wt. % of a compound of formula (I), 95 to 0.5 wt. % of a compound of formula (II) and a maximum of 10 wt. % of one of several compounds of general formula (III a), wherein A1-A32 which are independent...

20060241301 - Urea derivatives and their use as tyrosinkinase inhibitors: The invention relates to novel urea derivatives which inhibit tyrosinkinases, especially TIE-2, and Raf kinases and which are used in the treatment of tumors....

20060241302 - Morpholine derivatives: (wherein, R1 represents a heterocyclic group which may have a substituent, R2 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a substituent, R3 represents a cyclic hydrocarbon group which may have a substituent or a heterocyclic group which may have a...

20060241303 - Piperidine derivatives and process for their production: R4 has 1 to 6 carbon atoms; A, B, and D are the substituents of their respective rings each of which may be different or the same and are hydrogen, halogens, alkyl, hydroxy, alkoxy, or other substituents. A process of preparing such piperidine derivative compounds in substantially pure form is...

20060241304 - Method for preparing fused oxazinones: A method for preparing a fused oxazinone is disclosed in which a carboxylic acid is contacted with a sulfonyl chloride and an isatoic anhydride in the presence of a tertiary amine, the nominal mole ratio of said sulfonyl chloride to said carboxylic acid being from about 1.0 to 1.5 and...

20060235227 - Azo coupling reactions of hydrophobic compounds: A process for forming a diazo compound comprises reacting an organic compound bearing an acidic hydrogen with an aryl-diazonium salt in the presence of an inorganic base and a non-halogenated solvent. The process is simpler and more environmentally friendly than known processes....

20060235228 - Novel intermediate for the preparation of therapeutically active imidazopyridines: p

20060235229 - Novel process for the preparation of 2-aminomethylpyrimidine derivatives: The present invention relates to a novel process for the preparation of 2-amino-methylpyridine derivatives of the formula (I), comprising reacting in a first step 2-substituted pyridine derivatives of the formula (II), with a nitroalkane of the formula (III), in the presence of a base resulting in 2-nitromethylpyridine derivatives of the...

20060229451 - Process for producing high purity 3,5-dihydroxy-6-heptenoic acid derivative: A process for producing a high purity 3,5-dihydroxy6-heptenoic acid derivative by controlling the content of impurities such as denatured substances, is provided. When a 3,5-dihydroxy-6-heptenoic acid derivative is produced by a process which comprises a step of contacting the 3,5-dihydroxy-6-heptenoic acid derivative of the formula (1) wherein R is a...

20060229452 - Process for the oxidation of secondary amines into the corresponding nitroxides: The invention relates to a process for the preparation of secondary nitroxide radicals from their corresponding secondary amines by oxidation with an organic peracid, comprising the steps a) adding to a reaction vessel a secondary amine, optionally together with an organic solvent and in one batch a base selected from...

20060229453 - Process for the preparation of 5-[4-[2-[n-methyl-n-(2-pyridyl) amino] ethoxy] phenyl methyl] thiazolidine-2,4-dione maleate (rosiglitazone): A process for the preparation of 5-[4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]phenyl methyl]thiazolidine-2,4-dione maleate (the compound of Formula VI) comprising the steps of Coupling 2-[N-methyl-N-(2-pyridyl)amino]ethanol (the compound of Formula I) and 4-fluorobenzaldehyde (the compound of Formula II) in N,N-dimethylformamide, isolating the coupled product 4-[2-[N-methyl-N-(2-pyridyl)amino]ethoxy]benzaldehyde (the compound of Formula III), converting said isolated benzaldehyde compound of...

20060223997 - Synthesis of organometallic cyclometallated transition metal complexes: A process for forming a tris-cyclometallated complex comprises the step of reacting; a) an M(I) complex, wherein M represents Rh or Ir, and said complex comprises at least two ligands and contains at least two alkenyl groups pi-bonded to M, with b) a heterocyclic compound capable of forming a organometallic...

20060223998 - Synthetic lsd metabolite for preparing haptens used in an lsd metabolite immunoassay: A general method for the synthesis of OH-LSD and its analogs has been successfully developed. This method is convenient and efficient and allows preparation of a series of OH-LSD analogs with linkers attached at various (C-8, N-6 or N-1) positions....

20060223999 - Process for preparing montelukast and precursors thereof: The present invention provides a process for stereoselectively reducing 2-[3-[3-[2-(7-chloro-2-quinolinyl)ethenyl]-phenyl]-3-oxopropyyl]benzoic-acid methyl ester, to produce to produce methyl 2-[3-(S)-[3-[2-(7-chloro-2-quinolinyl)-ethenyl]phenyl]-3-hydroxypropyl]benzoate, and a process for producing montelukast or a salt thereof. The present invention further provides a process for purifying methyl 2-[3-(S)-[3-[2-(7-chloro-2-quinolinyl)-ethenyl]phenyl]-3-hydroxypropyl]benzoate. The reduction process of the present invention uses a chiral reagent...