Organic compounds -- part of the class 532-570 series inventions 04/06

20060089503 - Processes for producing optically active 2-thiomethyl-3-phenylpropionic acid derivative and for producing intermediate therefor: The present invention provides a process for simply producing an optically active 2-thiomethyl-3-phenylpropionic acid derivative useful as an intermediate for medicines from inexpensive raw materials. An optically active 2-hydroxymethyl-3-phenylpropionic acid ester derivative which can be relatively easily obtained by asymmetric reduction reaction with an enzyme is cyclized to an optically...

20060084817 - Synthesis of aldonolactones, aldarolactones, and aldarodilactones using gas sparging: Aldaric acids, aldonic acids, and their corresponding salts are cyclized to the corresponding lactone or dilactone using gas sparging to remove water....

20060084818 - Gas phase synthesis of methylene lactones using catalysts derived from hydrotalcite precursors: Process for converting certain lactones to their alpha-methylene substituted forms using (i) a catalyst derived from a hydrotalcite or (ii) a composite catalyst comprising the hydrotalcite-derived catalyst into which at least one of lithium, sodium, potassium, rubidium, cesium, magnesium, calcium, strontium, barium has been incorporated....

20060084819 - Total synthesis of myriaporones: Compounds of the general formula (I) or a pharmaceutically acceptable salt, derivative, prodrug or stereoisomer therefor are provided: wherein the substituent groups defined by R are each independently selected from the group consisting of H, SiR′3, SOR′, SO2X, C(═O)R′, C(═O)OR′, C(═O)NR′, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted...

20060079699 - Intermediate compounds and methods for synthesizing chemiluminescent dioxetane substrates: Methods for synthesizing 1,2-dioxetane compounds and intermediate compounds useful in the synthesis of these dioxetane compounds are described. The methods and intermediates allow for the efficient production of dioxetane substrates having electron withdrawing groups via a Homer Emmons coupling route....

20060079700 - Method for the preparation of citalopram: The invention provides a new and improved method for the preparation of 5-cyano-phtalid, which is a key intermediate in the preparation of the antidepressant compound citalopram....

20060074250 - Pentafluorosulfanyl-substituted thienothiophene monomers and conducting polymers: where X and X′ are independently H, halogen atoms (e.g., F, Cl, Br, and I), MgCl, MgBr, MgI, Sn(R′)3, where R′ comprises C1-6 alkyl or —OC1-6 alkyl, boronic acid, boronic ester, —CH═CHR″ (where R″ comprises H or C1-6 alkyl), —OC1-6 alkyl, —COOC1-6 alkyl, —S—COR″′ and —COR″′ (where R″′ comprises H...

20060074251 - Deoxoartemisinin analogs, process for their preparation, and anticancer agent comprising them: The present invention relates to a new deoxoartemisinin dimer and trimer, which have excellent anticancer activity and lower toxicity and are stable to acids, to a new deoxoartemisinin monomer of intermediate thereof, to preparations thereof, and to anticancer agents comprising the deoxoartemisinin dimer or trimer....

20060074252 - Synthetic route to dronabinol: Dronabinol, the tetrahydrocannabinol compound which comprises the active constituent of marijuana and is pharmaceutically useful as an antiemetic, is prepared by a process involving reaction of cis-menth-1-enc-3,8-diol with olivetol to form 1,3-dihydroxy-2-[(1R,6R)-6-(2-hydroxyprop-2-yl)-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene; and cyclizing the 1,3-dihydroxy-2-[(1R,6R)-6-(2-hydroxyprop-2-yl)-3-methylcyclohex-2-en-1-yl]-5-pentylbenzene so formed to obtain dronabinol. A novel synthesis of cis-menth-1-ene-3,8-diolis also provided....

20060074253 - Process for the preparation of citalopram: The present invention provides, inter alia, a novel process for the preparation of Citalopram, a known antidepressant....

20060074254 - Process for extracting taxanes: A method of extracting taxane products from biomass, which involves feeding the biomass into an pressurized liquid extraction unit and contacting the biomass with a halogenated C1 to C2 alkane solvent at a temperature of 100° C. or less and at sufficient pressure to keep the solvent in liquid form,...