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07/21/05 | 4 views | #20050159395 | Prev - Next | USPTO Class 514 | About this Page  514 rss/xml feed  monitor keywords

Nsaid-containing topical formulations that demonstrate chemopreventive activity

USPTO Application #: 20050159395
Title: Nsaid-containing topical formulations that demonstrate chemopreventive activity
Abstract: Disclosed herein are chemopreventive methods and topical formulations for the prevention and treatment of ultraviolet light-induced skin cancers, pre-cancerous lesions, and hyperproliferative disorders in mammals, such as humans, utilizing doses of non-steroidal anti-inflammatory drugs. Low doses of non-steroidal anti-inflammatory drugs are present in the topical formulations and allow continued regular use over an extended period of time to prevent such disorders. In particular, the present invention is particularly suitable for non-melanoma skin cancers as these cancers tend to appear in areas of the skin that have had excess sun exposure (head, neck and arms) meaning that the chemopreventive agent would not need to be applied over the entire body of the typical patient. Moreover, it is possible to identify “high-risk” individuals within the populations because people who report one episode of NMSC tend to have a high incidence of a subsequent episode. (end of abstract)
Agent: Hogan & Hartson LLPIPGroup, Columbia Square - Washington, DC, US
Inventors: Allan Evans, Ross McKinnon
USPTO Applicaton #: 20050159395 - Class: 514165000 (USPTO)
Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), Ortho-hydroxybenzoic Acid (i.e., Salicyclic Acid) Or Derivative Doai, Aspirin Per Se (i.e., 2-(acetyloxy)benozic Acid)

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Aryl-substituted derivatives of cycloalkyl and branched chain alkyl carboxylic acids useful as antinociceptive drugs for peripheral targets
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Compositions and methods of treatment for inflammatory diseases
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