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05/22/08 - USPTO Class 514 |  103 views | #20080119487 | Prev - Next | About this Page  514 rss/xml feed  monitor keywords

Novel non-imidazole compounds

USPTO Application #: 20080119487
Title: Novel non-imidazole compounds
Abstract: Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of Formula I in combination with a H1 receptor antagonist. Also disclosed are methods of treating various diseases or conditions, such as, for example, allergy, allergy-induced airway responses, and congestion (e.g., nasal congestion) using the compounds of Formula I. Also disclosed are pharmaceutical compositions comprising the compounds of Formula I. Disclosed are novel compounds of the formula (end of abstract)



Agent: Schering-plough Corporation Patent Department (k-6-1, 1990) - Kenilworth, NJ, US
Inventors: Robert G. Aslanian, Neng-Yang Shih, Pauline C. Ting, Michael Y. Berlin, Stuart B. Rosenblum, Kevin D. McCormick, Wing C. Tom, Christopher W. Boyce, Pietro Mangiaracina, Mwangi W. Mutahi, John J. Piwinski
USPTO Applicaton #: 20080119487 - Class: 51425504 (USPTO)

Novel non-imidazole compounds description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20080119487, Novel non-imidazole compounds.

Brief Patent Description - Full Patent Description - Patent Application Claims
  monitor keywords REFERENCE TO RELATED APPLICATIONS

This application claims the benefit of U.S. Provisional Application Ser. No. 60/240,901 filed Oct. 17, 2000.

BACKGROUND OF THE INVENTION

WO 95/14007 published May 26, 1995 discloses H3 receptor antagonists of the imidazole type.

WO99/24405 published May 20, 1999 discloses H3 receptor ligands of the imidazole type.

U.S. Pat. No. 5,869,479 issued Feb. 9, 1999 discloses compositions for the treatment of the symptoms of allergic rhinitis using a combination of at least one histamine H1 receptor antagonist and at least one histamine H3 receptor antagonist.

In view of the art's interest in compounds which affect H3 receptors, novel compounds that are antagonists of H3 receptors would be a welcome contribution to the art. This invention provides just such a contribution.

SUMMARY OF THE INVENTION

The present invention provides novel compounds of structure I.

or a pharmaceutically acceptable salt or solvate thereof, wherein

(1) R1 is selected from: (a) aryl; (b) heteroaryl; (c) heterocycloalkyl

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Imidazole derivatives
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Drug, bio-affecting and body treating compositions

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