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11/13/08 - USPTO Class 514 |  1 views | #20080280817 | Prev - Next | About this Page  514 rss/xml feed  monitor keywords

Modified amino acid for the inhibition of platelet aggregation

Title: Modified amino acid for the inhibition of platelet aggregation




Brief Patent Description - Full Patent Description - Patent Claims

The Patent Description & Claims data below is from USPTO Patent Application 20080280817, Modified amino acid for the inhibition of platelet aggregation.


1: A method of inhibiting platelet aggregation in a mammal comprising administering to said mammal a pharmaceutical composition comprising a modified amino acid, or a pharmaceutically acceptable salt thereof.

2: The method according to claim 1, wherein the pharmaceutical composition additionally comprises a pharmacologically active agents, and wherein the modified amino acid or salt thereof is present in an amount effective to inhibit platelet aggregation.

3: The method according to claim 1, wherein the modified amino acid is N-(−5-chlorosalicyloyl)-8-aminocaprylic acid (5-CNAC).

4: The method according to claim 2, wherein the pharmacologically active agent comprises heparin, insulin, parathyroid hormone or calcitonin.

5: The method according to claim 4, wherein the mammal is human and the calcitonin is salmon calcitonin.

6: The method according to claim 1 wherein the modified amino acid or pharmaceutically acceptable salt thereof is present in an amount of about 25 mg to about 400 mg.

7: The method according to claim 6, wherein the modified amino acid or pharmaceutically acceptable salt thereof is present in an amount of about 100 mg to about 200 mg.

8: The method according to claim 2, wherein the pharmacologically active agent is present in an amount of 0.05% to 70% by weight relative to the total weight of the pharmaceutical composition.

9: The method according to claim 2, wherein the pharmaceutical composition comprises calcitonin and 5-CNAC or a pharmaceutically acceptable salt thereof.

10: A pharmaceutical composition comprising a platelet aggregation inhibiting amount of a modified amino acid, or a pharmaceutically acceptable salt thereof.

11: The pharmaceutical composition according to claim 10, further comprising a pharmacologically active agent, wherein the modified amino acid or salt thereof is present in an amount effective to inhibit platelet aggregation.

12-

13. (canceled)

Brief Patent Description - Full Patent Description - Patent Claims

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