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08/16/07 - USPTO Class 210 |  49 views | #20070187317 | Prev - Next | About this Page  210 rss/xml feed  monitor keywords

Mobile filtration facility and methods of use

USPTO Application #: 20070187317
Title: Mobile filtration facility and methods of use
Abstract: A mobile first housing bounds a substantially sterile clean room, a filtration room, and at least one change room communicating between clean room. A fluid filtration system is disposed within the first housing, the filtration system includes a first support container in which a disposable fill bag is disposed. A disposable fluid line extends between the fill bag and the at least one filter. A support bin is also disposed within the first housing. A disposable pooling bag is disposed within the support bin, the pooling bag being in fluid communication with the at least one filter. A disposable fill line has a first end in fluid communication with the pooling bag and an opposing second end disposed within the clean room. (end of abstract)



Agent: Workman Nydegger (f/k/a Workman Nydegger & Seeley) - Salt Lake City, UT, US
Inventors: Gary H. Graetz, Tracy Zilles
USPTO Applicaton #: 20070187317 - Class: 210321600 (USPTO)

Related Patent Categories: Liquid Purification Or Separation, Casing Divided By Membrane Into Sections Having Inlet(s) And/or Outlet(s)

Mobile filtration facility and methods of use description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20070187317, Mobile filtration facility and methods of use.

Brief Patent Description - Full Patent Description - Patent Application Claims
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BACKGROUND OF THE INVENTION

[0001] 1. The Field of the Invention

[0002] The present invention relates to mobile filtration facilities used in filtering liquids derived from mammalian blood and other fluids.

[0003] 2. The Relevant Technology

[0004] Mammalian blood serum, such as fetal bovine serum, calf serum, and the blood serum of other mammals, is broadly used in the growth and development of cell cultures. Although serum can be derived from the blood of all animals, it has been found that serum derived from a fetus or new born has enhanced properties for cell growth. In part, this is because such serums are high in growth factors and hormones which enhance cell growth.

[0005] Most mammalian blood serum is obtained at established slaughterhouses. For example, fetal bovine serum is typically obtained from fetuses that are removed from cattle that are slaughtered for beef. The fetuses are taken to an area of the slaughterhouse where the blood is harvested from the fetuses. The blood is then processed so as to remove the serum component. The raw unfiltered serum is then placed in bottles and quickly frozen.

[0006] Because there are relatively few fetuses and such fetuses have a rather small amount of blood, fetal bovine serum is a precious and expensive commodity. Prior to use of the serum, the serum must be filtered under highly stringent conditions that require the use of a sterile clean room. Furthermore, most filtering processes pass the serum through different stainless steel tanks and fixed lines that must be repeatedly cleaned and certified between batches. This cleaning requires the use and disposal of hazardous cleaning chemicals. Although a clean room and the required filtering equipment can be erected at each slaughterhouse, this is generally not cost efficient. That is, because there is such a small volume of fetal bovine serum harvested at a given slaughterhouse, it is difficult for a single slaughterhouse to recoup the expense of building, operating, manning, and maintaining a sterile clean room and the filtration equipment.

[0007] As a result, the traditional approach to filtering serum is to ship the serum to an established filtration facility. The problem with this approach, however, is that slaughterhouses are widely spaced apart throughout the world and there are relatively few filtration facilities. Because serum must remain frozen, the serum becomes relatively expensive to ship over long distances to the established filtration facilities. Furthermore, because of various blood diseases, some countries will not allow blood products to be transported into their country for filtering and/or sale.

[0008] In addition, it is often critically important to the purchasers of filtered serum that they can establish and certify where a particular serum was derived and filtered. Acquiring a serum in one country, filtering the serum in a second country, and then attempting to sell the serum in a third country is largely prohibitive. Such movement between countries makes is difficult to obtain required import licenses and to provide sufficient assurance to the end purchasers as to the origin and history of the serum.

[0009] Similar types of problems are also encountered in filtering blood components which are used in clinical chemistry controls. For example, human donated blood that has expired is typically processed to extract the serum, plasma, and fractions thereof which can subsequently be used in clinical chemistry controls. Again, prior to use such blood components must be filtered under highly stringent conditions that require the use of a sterile clean room and a filtration system. The expired blood is often found at blood banks and other storage facilities located at sporadic locations throughout the world. As with fetal bovine serum, filtering the blood components is cost prohibitive to the storage facilities. The blood and/or bloods products are thus typically shipped to filtration facilities. Again, however, the shipping of blood products requires refrigerated shipping which adds significant cost to the final blood products. Furthermore, attempts to transport blood products between different countries can be problematic.

[0010] Accordingly, what is needed are methods and systems that can be used to efficiently filter and/or sterilize blood products and other types of liquids that are produced and/or collected at different facilities around the world.

BRIEF DESCRIPTION OF THE DRAWINGS

[0011] Various embodiments of the present invention will now be discussed with reference to the appended drawings. It is appreciated that these drawings depict only typical embodiments of the invention and are therefore not to be considered limiting of its scope.

[0012] FIG. 1 is a perspective view of a filtration facility including a first housing and a second housing;

[0013] FIG. 2 is a top cross sectional plan view of the first housing shown in FIG. 1;

[0014] FIG. 3 is a top cross sectional plan view of the second housing shown in FIG. 1;

[0015] FIG. 4 is a front view of a filtration system disposed within the second housing shown in FIG. 3;

[0016] FIG. 5 is cross sectional side view of a fill container assembly of the filtration system shown in FIG. 4;

[0017] FIG. 6 is a perspective view of a pooling bag assembly of the filtration system shown in FIG. 4;

[0018] FIG. 7 is a partially exploded perspective view of a pooling bag of the pooling bag assembly shown in FIG. 6;

[0019] FIG. 8 is a cross sectional side view showing a connection of a dip tube to the pooling bag shown in FIG. 6;

[0020] FIG. 9 is a partial cross sectional top plan view of a fill line assembly of the pooling bag assembly shown in FIG. 6;

[0021] FIG. 10 is a top plan view of the pooling bag assembly shown in FIG. 6 in a collapsed state and sealed within double bags;

[0022] FIG. 11 is a perspective view of a support bin of the filtration system shown in FIG. 4;

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