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12/08/05 - USPTO Class 514 | 71 views | #20050272825 | Prev - Next | About this Page

Methods for the inhibition of atrophy or for treatment or prevention of atrophy-related symptoms in women

Title: Methods for the inhibition of atrophy or for treatment or prevention of atrophy-related symptoms in women

Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), Ether Doai, Benzene Ring Containing, Plural Oxygens, Acyclic Carbon To Carbon Unsaturation

Brief Patent Description - Full Patent Description - Patent Claims

The Patent Description & Claims data below is from USPTO Patent Application 20050272825, Methods for the inhibition of atrophy or for treatment or prevention of atrophy-related symptoms in women.

What is claimed is:

1. A method for inhibition of skin atrophy, or epithelial or mucosal atrophy in women, said method comprising administering to the woman an effective amount of the compound of formula (I) 4or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof.

2. The method according to claim 1 wherein compound (I) is ospemifene.

3. The method according to claim 1 wherein the atrophy is urogenital atrophy.

4. The method according to claim 2 wherein the atrophy is urogenital atrophy.

5. A method for treatment or prevention of symptoms related to skin atrophy, or to epithelial or mucosal atrophy in women, said method comprising administering to the woman an effective amount of the compound of formula (I) 5or a geometric isomer, a stereoisomer, a pharmaceutically acceptable salt, an ester thereof or a metabolite thereof.

6. The method according to claim 5 wherein compound (I) is ospemifene.

7. The method according to claim 5 wherein the atrophy is urogenital atrophy.

8. The method according to claim 7 wherein the symptoms are vaginal symptoms.

9. The method according to claim 8 wherein the vaginal symptoms are irritation, itching, burning, maladorous discharge, infection, dyspareunia, leukorrhea, vulvar pruritus, feeling of pressure, postcoital bleeding, vaginal dryness and difficulty in sexual arousal.

10. The method according to claim 1 wherein compound (I), its isomer, salt or ester is administered orally, topically, transdermally, intravaginally or subcutaneously.

11. The method according to claim 5 wherein compound (I), its isomer, salt or ester is administered orally, topically, transdermally, intravaginally or subcutaneously.

12. The method according to claim 7 wherein the symptoms are urinary symptoms.

Brief Patent Description - Full Patent Description - Patent Claims

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