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Methods and dosage forms for the treatment of human cancers

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Title: Methods and dosage forms for the treatment of human cancers.
Abstract: Methods for the treatment of human cancers, daily dosage forms for cancer patients, and methods of formulating the dosage forms are provided wherein the daily dosage form contains from about 10-6,000 mg of each of β-sitosterol, isovanillin, and linolenic acid. Preferably, the dosage forms are formulated by first creating an aqueous decoction of Arum palaestinum Boiss, followed by fortification of the decoction with additional quantities of β-sitosterol, isovanillin, and linolenic acid. ...

Browse recent Life Plus, LLC patents - Sterling, KS, US
Inventors: Gene H. Zaid, Thomas W. Burgoyne, Beth Ann Wolf
USPTO Applicaton #: #20120108556 - Class: 514171 (USPTO) - 05/03/12 - Class 514 
Drug, Bio-affecting And Body Treating Compositions > Designated Organic Active Ingredient Containing (doai) >Cyclopentanohydrophenanthrene Ring System Doai >With Additional Active Ingredient

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The Patent Description & Claims data below is from USPTO Patent Application 20120108556, Methods and dosage forms for the treatment of human cancers.

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This is a continuation of identically-titled U.S. patent application Ser. No. 12/905,847, filed Oct. 15, 2010, which is incorporated herein by reference in its entirety.


1. Field of the Invention

The present invention is directed to methods for the treatment of human cancers, daily dosage forms for administration to cancer patients, and methods of formulating such dosage forms. More particularly, the invention is concerned with the administration of daily dosage forms (e.g., aqueous mixtures, capsules, pills, or tablets) containing from about 10-6,000 mg of each of β-sitosterol, isovanillin, and linolenic acid. Such treatment provides a marked decline and/or elimination of cancerous tumors, particularly those of the bladder, breast, liver, and lung, and a corresponding enhancement of the wellness and lifestyles of the treated patients.

2. Description of the Prior Art

Cancer is a generic term for a large group of diseases that can affect any part of the body. Other terms used are malignant tumours and neoplasms. One defining feature of cancer is the rapid creation of abnormal cells that grow beyond their usual boundaries, and which can then invade adjoining parts of the body and spread to other organs. This process is referred to as metastasis. Metastases are the major cause of death from cancer.

Cancer is a leading cause of death worldwide. The disease accounted for 7.4 million deaths (or around 13% of all deaths worldwide) in 2004. The main types of cancer leading to overall cancer mortality each year are: lung (1.3 million deaths/year) stomach (803 000 deaths) colorectal (639 000 deaths) liver (610 000 deaths) breast (519 000 deaths). More than 70% of all cancer deaths occurred in low- and middle-income countries. Deaths from cancer worldwide are projected to continue rising, with an estimated 12 million deaths in 2030.

The most frequent types of cancer worldwide (in order of the number of global deaths) are: Among men—lung, stomach, liver, colorectal, oesophagus and prostate Among women—breast, lung, stomach, colorectal and cervical.

Cancer arises from one single cell. The transformation from a normal cell into a tumour cell is a multistage process, typically a progression from a pre-cancerous lesion to malignant tumours. These changes are the result of the interaction between a person\'s genetic factors and three categories of external agents, including: physical carcinogens, such as ultraviolet and ionizing radiation chemical carcinogens, such as asbestos, components of tobacco smoke, aflatoxin (a food contaminant) and arsenic (a drinking water contaminant) biological carcinogens, such as infections from certain viruses, bacteria or parasites.

Some examples of infections associated with certain cancers: Viruses: hepatitis B and liver cancer, Human Papilloma Virus (HPV) and cervical cancer, and human immunodeficiency virus (HIV) and Kaposi sarcoma. Bacteria: Helicobacter pylori and stomach cancer. Parasites: schistosomiasis and bladder cancer.

Aging is another fundamental factor for the development of cancer. The incidence of cancer rises dramatically with age, most likely due to a buildup of risks for specific cancers that increase with age. The overall risk accumulation is combined with the tendency for cellular repair mechanisms to be less effective as a person grows older.

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