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Method for selectively transducing pathologic mammalian cells using a tumor suppressor gene   

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Abstract: A method for transducing a pathologic hyperproliferative mammalian cell is provided by this invention. This method requires contacting the cell with a suitable retroviral vector containing a nucleic acid encoding a gene product having a tumor suppressive function. Also provided by this invention is a method for treating a pathology in a subject caused by the absence of, or the presence of a pathologically mutated tumor suppressor gene. ...

Agent: Townsend And Townsend And Crew, LLP - San Francisco, CA, US
Inventors: H. Michael Shepard, Nancy Kan
USPTO Applicaton #: #20070237753 - Class: 424093210 (USPTO) - 10/11/07 - Class 424 
Related Terms: Gene Product   Mammalian Cells   Pathologic   Pathology   Retrovir   Retroviral Vector   Suppressor Gene   Tumor Suppressor Gene   
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Related Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Whole Live Micro-organism, Cell, Or Virus Containing, Genetically Modified Micro-organism, Cell, Or Virus (e.g., Transformed, Fused, Hybrid, Etc.), Eukaryotic Cell
The Patent Description & Claims data below is from USPTO Patent Application 20070237753, Method for selectively transducing pathologic mammalian cells using a tumor suppressor gene.

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Gene Product   Mammalian Cells   Pathologic   Pathology   Retrovir   Retroviral Vector   Suppressor Gene   Tumor Suppressor Gene   


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