Method and apparatus for use of thermally switching proteins in sensing and detecting devices

Abstract: An apparatus and method for detecting infrared radiation is provided which comprises a temperature-sensing helical coiled-coil protein such as TIpA, CC1, collagen or myosin, incorporated into an electrically conductive film or gel deposited onto an electrically conductive medium, means for recording changes in conductivity or resistance of the conductive film or gel caused by the presence of infrared radiation and its effect on the thermal-sensing protein, and means to analyze the changes in conductivity or resistance in the conductive film caused thereby so as to determine if infrared radiation is present. By virtue of the present invention, a “biomimetic” infrared sensor is provided which can integrate a recombinantly produced thermally sensitive protein in a conductive polymer matrix, such as a film or gel, and provide a low-cost, lightweight, conformable, and disposable infrared detecting device having high sensitivity and excellent dynamic range. (end of abstract)