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Metal-containing compositions, preparations and usesRelated Patent Categories: Plant Protecting And Regulating Compositions, Plant Growth Regulating Compositions (e.g., Herbicides, Etc.)Metal-containing compositions, preparations and uses description/claimsThe Patent Description & Claims data below is from USPTO Patent Application 20060189483, Metal-containing compositions, preparations and uses. Brief Patent Description - Full Patent Description - Patent Application Claims
[0001] It is well established that minerals i.e. traces of selected metal elements are required as part of the human diet for good health. Mineral deficiencies can lead to poor health and specific disorders. Amongst the minerals that the body requires, there are, for example, the metals zinc, magnesium, copper, iron, and selenium. The human body requires traces of such minerals in soluble form whereby the corresponding metallic ions are bio-available within the bloodstream. [0002] With the increase in highly processed and convenience foods, there are concerns that the typical diet in today's conditions may not contain sufficient vitamins and/or minerals. Accordingly vitamin and mineral supplements are widely available without prescription on the basis that they are foodstuff components and not medicaments. [0003] This invention is particularly concerned with mineral metal compositions, their preparation and uses within a mineral `delivery` system for humans or animals. It is known that mineral salts by themselves, e.g. zinc sulphate, iron sulphate and the like will dissociate in aqueous solution to form the corresponding ions e.g. Zn.sup.2+ and Fe.sup.2+ with SO.sub.4.sup.2-. However, it has been observed that the metallic mineral ions in solution within the bloodstream are not readily bio-available in the sense of being available for uptake by cells. Accordingly there are at least two mineral `binder` systems available for enhancing bio-availability of these ions. Most mineral supplement compositions presently available are based upon an inorganic chelate binder system. In such compositions, the required mineral element e.g. zinc, magnesium or the like is chemically bonded to a chelate such that bio-availability of the mineral ions is still significantly impaired. The digestive system has difficulty in leaching the mineral element away from the chelate binder for cellular uptake. This limits their bio-availability. Chelate based mineral supplements apparently limit the body's absorption of the elemental mineral to some 7 to 10% of that presented. It is suggested that the remaining mineral content is not absorbed into the bloodstream, but is passed in the urine or faeces. Chelate-bound iron mineral supplements, in particular, can cause constipation as the chelate can act as a flocculent in the large intestine. It is desirable that such disadvantage be overcome in an alternative mineral `delivery` system with improved bio-availability of the mineral elements. [0004] Another mineral supplement composition is based upon a mineral salt combined with an organic glutamate binder. One product based upon the glutamate bound mineral delivery system is a lozenge containing zinc for oral ingestion. However, not only does the glutamate delivery system demonstrate restricted mineral element/ion bio-availability in similar fashion to the chelates described above, but also zinc glutamate lozenges in particular tend to leave undesirable coloured stains in the mouth. Accordingly it is also desirable to overcome this particular disadvantage in an alternative mineral delivery system providing better mineral element bio-availability. [0005] In consequence it can be summarised that the existing chelate and glutamate bound mineral compositions deliver such mineral elements into the bloodstream but only a small proportion of the total content of the respective mineral element, and over a relatively lengthy period of time whereby specific mineral bio-availability is limited. [0006] The present inventor has considered the existing mineral delivery systems such as the chelate and glutamate delivery systems and their disadvantages. The present invention provides inter alia, alternative mineral delivery systems based on quite different components which have been found to improve specific mineral bio-availability in terms of not only bloodstream quantities but also bloodstream absorption time. [0007] The present inventor provides several aspects to his invention, based upon mineral or other metallic element--containing compositions, methods for preparing such compositions and uses of such compositions which encompass several distinct technical fields apart from the field of mineral supplements for the human or animal diet, namely uses of the compositions for medical conditions in the treatment of a disease or disorder, treating or purifying water or sewage, use as an algaecide, fungicide and disinfectant and uses in treating metal substrates to control corrosion. [0008] Accordingly in a first aspect of this invention there is provided a metal-containing composition substantially comprising: [0009] (i) at least one water soluble metal compound which forms metal ions when dissolved in water, [0010] (ii) at least one metal ion modifier as herein defined, [0011] (iii) at least one acid, and [0012] (iv) water said composition having a pH of less than 6 and an electrolytic potential in excess of 10 millivolts. [0013] The term `metal` is used herein to encompass semi-metals of a mineral nature, e.g. selenium. [0014] Such compositions preferably essentially consist of the aforesaid components with any preferred additives and more preferably consist of such ingredients, optional additives and the balance being any inevitable impurities. [0015] In a second aspect of this invention there is provided a method of making a composition as defined in the first aspect comprising dissolving (i) in distilled water, adding (ii) and mixing or allowing to dissolve, then adding (iii) whilst simultaneously monitoring the pH and electrolytic potential of the composition until a required value of each measurement is obtained. [0016] A third aspect of this invention provides the use of a composition as defined in the first aspect in medicine, for example the use of such a composition for preventing or treating one or more of the following pathogenic disorders, namely bacterial, fungal or viral infection, retroviral infection such as AIDS or Hepatitis C, particularly including copper containing such compositions for treating one or more of the following diseases, namely cholera, salmonella, shigella, E. Coli and chlamydia. [0017] A fourth aspect of this invention provides the use of a composition as defined in the first aspect, in the preparation of a medicament for use in the treatment of a disease or disorder, such as one or more of the aforementioned diseases or disorders. [0018] The invention also provides in a fifth aspect the use of a composition as defined in the first aspect in the treatment of water or water containing materials or sewage, effluent, commercial, domestic waste products as a bactericide, or algaecide, flocculent viricide and/or fungicide. [0019] A sixth aspect of the present invention provides the use of a composition as defined in the first aspect to form a corrosion resistant coating or plating for metal substrates, to act as a sealant against metal corrosion. [0020] In a seventh aspect the present invention provides the use of a composition as defined in the first aspect as a bactericidal and/or fungicidal preservative against the bacterial or fungal deterioration of edible foodstuffs. [0021] The metal ion modifier is preferably a binder other than chelate or glutamate effective to transport ions incorporating the metallic mineral element through the digestive system and into the bloodstream in bioavailable form. Such binder can be, for example, a complexing, buffering or sequestering agent. It is most preferred to use soluble ammonium compounds, such as one or more of the following ammonium salts: ammonium chloride, sulphate or phosphate. [0022] Such metal ion modifiers appear particularly effective in retaining and sustaining electrolytic potential. [0023] The present invention is based on the inventor's discoveries that an improved metallic mineral delivery system for the human or animal bloodstream and other uses can be formulated from selected metal-containing electrolytes in acidic aqueous media which demonstrate a measurable electrolytic potential which is stable for a significant period of time. Such compositions have surprisingly been found, inter alia, when ingested or absorbed to make the mineral ions more rapidly available to the body for cellular uptake, and more efficiently and sustainably in terms of percentage by weight of bio-available mineral within the bloodstream, after a given time. Additionally it would appear that the ions incorporating the metallic mineral element are more bio-active due to enhanced beneficial effects which have been observed. The ions incorporating the metallic mineral element appear to be polarised, with an overall cationic charge. Accordingly, within the present compositions, the metallic element effects appear to be synergistically improved by the metal ion modifier. In particular this appears to be the case with zinc and magnesium compositions. Continue reading about Metal-containing compositions, preparations and uses... Full patent description for Metal-containing compositions, preparations and uses Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Metal-containing compositions, preparations and uses patent application. ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. 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