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Merck And Co., Inc patents

The following is a sampling of recent Merck And Co., Inc patent applications (USPTO Patent Application #, Patent Title) sorted by month.

April 2010 - Merck And Co., Inc patents

20100099743 - Rna interference mediated inhibition of checkpoint kinase-1 (chk-1) gene expression using short interfering nucleic acid (sina)
20100099744 - Rna interference mediated inhibition of matrix metalloproteinase 13 (mmp13) gene expression using short interfering nucleic acid (sina)
20100099750 - Rna interference mediated inhibition of muscarinic colinergic receptor gene expression using short interfering nucleic acid (sina)
20100099673 - Decahydroquinoline analogs as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases
20100099695 - Hcv ns3 protease inhibitors
20100099716 - Cetp inhibitors
20100099923 - Process for the preparation of bicyclo[3.1.0]hexanols
20100092505 - Method for shielding functional sites or epitopes on proteins
20100093665 - Silylated piperidine derivatives
20100093759 - Bicyclic anilide heterocyclic cgrp receptor antagonists
20100093779 - Hcv ns3 protease inhibitors
20100093811 - Hiv protease inhibitors
20100087360 - Heterocycle-substituted benzimidazole derivative
20100087419 - Hiv integrase inhibitors
20100087446 - 2-substituted indole derivatives as calcium channel blockers
20100081643 - Novel cyclic benzimidazole derivatives useful as anti-diabetic agents
20100081642 - Cb-1 receptor modulator pharmaceutical formulations
20100081696 - Fluoro substituted cycloalkanoindoles, compositions containing such compounds and methods of treatment

March 2010 - Merck And Co., Inc patents

20100074888 - Animal having modification in mgat2 gene
20100075907 - Neuromedin u receptor agonists and uses thereof
20100076059 - Method of evaluating compound efficacious in treating obesity by using slc25a10
20100075970 - Inhibitors of akt activity
20100075987 - Acyl bipiperidinyl compounds, compositions containing such compounds and methods of treatment
20100076002 - Method of treating atherosclerosis, dyslipidemias and related conditions and pharmaceutical compositions
20100076004 - Bicyclic spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease
20100076046 - Antiviral indoles
20100069347 - Heterocyclyl-substituted anti-hypercholesterolemic compounds
20100069359 - Constrained spirocyclic compounds as cgrp receptor antagonists
20100069419 - Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease
20100069452 - Mineralocorticoid receptor modulators
20100062516 - Expression of class 2 mannosidase and class iii mannosidase in lower eukaryotic cells
20100062523 - Expression of class 2 mannosidase and class iii mannosidase in lower eukaryotic cells
20100063013 - Cathepsin cysteine protease inhibitors
20100063024 - Dihydropyrazolopyrimidinone derivatives
20100063032 - Substituted pyrido[2,3-d]pyrimidine derivatives as cannabinoid-1 receptor modulators
20100063056 - Bipyridine carboxamide orexin receptor antagonists
20100063091 - Renin inhibitors
20100063308 - Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
20100056498 - Substituted monocyclic cgrp receptor antagonists
20100056516 - 1-hydroxy naphthyridine compounds as anti-hiv agents
20100056550 - Tricyclic heteroaromatic compounds as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20100056563 - Novel 1.8-naphthyridine compounds
20100056580 - Novel crystalline salt form of an antidiabetic compound
20100056597 - Indoledione derivative

February 2010 - Merck And Co., Inc patents

20100048551 - Tricyclic compounds useful as inhibitors of kinases
20100048555 - Imidazothiazole derivatives as mark inhibitors
20100048600 - Novel benzimidazole derivatives
20100048623 - Piperidines and related compounds for the treatment of alzheimer's disease
20100048717 - Cathepsin b inhibitors
20100048888 - Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
20100040610 - Antagonists of pcsk9
20100040611 - Antagonists of pcsk9
20100041026 - Method for identiflying modulators of rufy2 useful for treating alzheimer's disease
20100041097 - Synthetic gene control region
20100041102 - Antagonists of pcsk9
20100041652 - Tyrosine kinase inhibitors
20100041660 - Novel 2-pyridinecarboxamide derivatives
20100041667 - Piperidine and pyrrolidine beta-secretase inhibitors for the treatment of alzheimer's disease
20100041680 - Piperidine derivatives
20100041724 - Process for synthesizing a cetp inhibitor
20100041893 - Formation of tetra-substituted enamides and stereoselective reduction thereof
20100035818 - Optimized expression of hpv 52 l1 in yeast
20100035835 - Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
20100035857 - Anti-hypercholesterolemic compounds
20100035931 - Tripyridyl carboxamide orexin receptor antagonists
20100035991 - Amide base salts of saha and polymorphis thereof
20100036135 - Process for making hydroisoindoline tachykinin receptor antagonists
20100028333 - Receptor for amyloid beta and uses thereof
20100028951 - Production of glycoproteins with modified fucosylation
20100029012 - Method for identifying modulators of the nrf2-keap1-arep pathway
20100029666 - Macrocyclic quinoxaline compounds as hcv ns3 protease inhibitors
20100029678 - Diuretics
20100029688 - Bipiperidinyl compounds, compositions containing such compounds and methods of treatment
20100029697 - Substituted pyrido[3,2-e][1,2,4]triazolo[4,3-c]pyrimidine derivatives as cannabinoid-1 receptor modulators
20100029701 - Macrocyclic spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease
20100029726 - Cyclohexanesulfonyl derivatives as glyt1 inhibitors to treat schizophrenia
20100029736 - 2-substituted proline bis-amide orexin receptor antagonists

January 2010 - Merck And Co., Inc patents

20100021991 - Methods for producing modified glycoproteins
20100022404 - Gene/protein marker for prediction or diagnosis of pharmacological efficacy of aurora a inhibitor
20100022468 - Nucleoside cyclic phosphoramidates for the treatment of rna-dependent rna viral infection
20100022477 - Fused aromatic ptp-1b inhibitors
20100022573 - Inhibitors of akt activity
20100022598 - Substituted inmidazoles as bombesin receptor subtype-3 modulators
20100022630 - Method of treatment using fatty acid synthesis inhibitors
20100022771 - Reaction apparatus, and reaction method
20100015218 - Compositions and methods for potentiated activity of biologically active molecules
20100016308 - Tetrahydroindole derivatives for treatment of alzheimer's disease
20100016335 - Novel aminopyridine derivatives having aurora a selective inhibitory action
20100016555 - N-acetylglucosaminyltransferase iii expression in lower eukaryotes
20100016561 - N-acetylglucosaminyltransferase iii expression in lower eukaryotes
20100017894 - Mutants of human app and their use for the production of transgenice animals
20100009461 - Npcil1 (npc3) and methods of identifying ligands thereof
20100009866 - Surface display of whole antibodies in eukaryotes
20100009957 - Novel inhibitors of beta-lactamase
20100009959 - Pentacyclic indole derivatives as antiviral agents
20100009962 - Benzyl-substituted quinolone m1 receptor positive allosteric modulators
20100009967 - Solid dosage formulations of telcagepant potassium
20100009987 - Aminothiazole derivatives as inhibitors of mark
20100010041 - Difluorinated piperidines for treatment of alzheimer's disease and related conditions
20100003276 - Methods for treating anthrax and inhibiting lethal factor
20100003665 - Real-time hpv pcr assays
20100004158 - Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
20100004184 - Anti-hypercholesterolemic compounds
20100004229 - Potassium channel inhibitors
20100004245 - Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20100004280 - Substituted imidazoles as bombesin receptor subtype-3 modulators
20100004287 - Cyclic derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase

December 2009 - Merck And Co., Inc patents

20090325862 - Histone deacetylase inhibitors for the treatment of neurodegeneration
20090325936 - Imidazopyridine analogs as cb2 receptor modulators, useful in the treatment of pain, respiratory and non-respiratory diseases
20090325953 - P38 kinase inhibiting agents
20090325990 - Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
20090325991 - Spirolactam bicyclic cgrp receptor antagonists
20090317840 - Automated determination of chlamydia infection-forming units
20090317850 - Crystal structure of human 70kd ribosomal protein s6 kinase 1 kinase domain
20090318476 - Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090318518 - Indole and indoline cyclopropyl amide derivatives as ep4 receptor antagonists
20090318541 - Benzothiophene hydroxamic acid derivatives with carbamate, urea, amide and sulfonamide substitutions
20090318560 - Formulations for cathepsin k inhibitors
20090312241 - Macrocyclic compounds as antiviral agents
20090312303 - Antidiabetic bicyclic compounds
20090312335 - Hiv integrase inhibitors
20090304594 - Methods for predicting treatment response based on the expression profiles of protein and transcription biomarkers
20090305314 - Upregulation of adamts4 protease activity for the treatment of alzheimer's disease
20090306037 - Combination of a dipeptidyl peptidase-iv inhibitor and a cannabinoid cb1 receptor antagonist for the treatment of diabetes and obesity
20090306058 - Sulphone derivatives for treatment of cancer
20090306071 - Inhibitors of janus kinases
20090306076 - Morpholine carboxamide prokineticin receptor antagonists
20090306115 - Phenyl ethyne compounds
20090306169 - Use of fused pyrrole carboxylic acids for the treatment of neurodegenerative and psychiatric diseases and d-amino acid oxidase inhibitors
20090306202 - D-homoandrosta-17-yl carbamate derivatives as selective glucocorticoid receptor ligands
20090306375 - Process for production of 4(3h)-quinazolinone derivative
20090298046 - Assays for histone deacetylase 1/2 selective inhibitors
20090298073 - Kidney toxicity biomarkers
20090298856 - 2,3 substituted fused bicyclic pyrimidin-4(3h)-ones modulating the function of the vanilliod-1receptor (vr1)
20090298949 - Aminoalkylphenols, methods of using and making the same

November 2009 - Merck And Co., Inc patents

20090291941 - Tyrosine kinase inhibitors
20090291955 - Azacyclohexane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090291965 - Histone deacetylase inhibitors with aryl-pyrazolyl-motifs
20090291988 - Reversible inhibitors of monoamine oxidase a and b
20090282913 - Method and apparatus for measuring the volume of an animal paw
20090286765 - Therapeutic agents
20090286772 - 2-(phenyl or heterocyclic)-1h-phenanthro[9,10-d]imidazoles
20090286777 - 5,6,fused pyrrolidine compounds useful as tachykinin receptor antagonists
20090286825 - Indole derivatives as crth2 receptor antagonists
20090281080 - Spirohydantoin tricyclic cgrp receptor antagonists
20090281080 - Spirohydantoin tricyclic cgrp receptor antagonists
20090281103 - Renin inhibitors
20090281103 - Renin inhibitors
20090281117 - Substituted imidazole-4-carboxamides as cholecystokinin -1 receptor modulators
20090281117 - Substituted imidazole-4-carboxamides as cholecystokinin -1 receptor modulators
20090281154 - Ophthalmic compositions for treating ocular hypertension
20090281154 - Ophthalmic compositions for treating ocular hypertension
20090281306 - Process for the preparation of cgrp antagonist
20090281306 - Process for the preparation of cgrp antagonist
20090275515 - 2-hydroxy-2-phenylthiophenylpropionamides as androgen receptor modulators
20090275515 - 2-hydroxy-2-phenylthiophenylpropionamides as androgen receptor modulators
20090275550 - Pyridyl amide t-type calcium channel antagonists
20090275550 - Pyridyl amide t-type calcium channel antagonists
20090275617 - Aryl-substituted nitrogen-containing heterocyclic compounds
20090275617 - Aryl-substituted nitrogen-containing heterocyclic compounds
20090275619 - Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors
20090275619 - Amide substituted indazole and benzotriazole derivatives as poly(adp-ribose)polymerase (parp) inhibitors

October 2009 - Merck And Co., Inc patents

20090269278 - Radiolabeled glycine trasporter inhibitors
20090269278 - Radiolabeled glycine trasporter inhibitors
20090270351 - Phosphorus derivatives as histone deacetylase inhibitors
20090270351 - Phosphorus derivatives as histone deacetylase inhibitors
20090270395 - Ep4 receptor agonist, compositions and methods thereof
20090270395 - Ep4 receptor agonist, compositions and methods thereof
20090270406 - Combination therapy for the treatment of urinary frequency, urinary urgency and urinary incontinence
20090270406 - Combination therapy for the treatment of urinary frequency, urinary urgency and urinary incontinence
20090270434 - Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090270434 - Azacycloalkane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090270436 - Spirochromanon derivatives
20090270436 - Spirochromanon derivatives
20090270451 - Piperdine glycine transporter inhibitors
20090270451 - Piperdine glycine transporter inhibitors
20090270467 - Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090270467 - Aminocyclohexanes as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090270477 - Polymorphs of a hydroisoindoline tachykinin receptor antagonist
20090270477 - Polymorphs of a hydroisoindoline tachykinin receptor antagonist
20090270511 - Prodrugs of inhibitors of cathepsin s
20090270511 - Prodrugs of inhibitors of cathepsin s
20090264405 - Cetp inhibitors
20090264426 - Bicyclic aromatic substituted pyridone derivative
20090264436 - Cb-1 receptor modulator formulations
20090264473 - Novel crystalline forms of antidiabetic compounds
20090264476 - Cb-1 receptor modulator formulations
20090264479 - Papain family cysteine protease inhibitors for the treatment of parasitic diseases
20090264622 - Rhesus monkey nur77
20090258851 - Diaryl substituted alkanes
20090258852 - Inhibitors of checkpoint kinases
20090258853 - Somatostatin agonists
20090258862 - Niacin receptor agonists, compositions containing such compounds and methods of treatment
20090258871 - Aza-substituted spiro derivatives
20090258884 - Substituted amides
20090258885 - Diphenylmethane derivatives as inhibitors of leukotriene biosynthesis
20090258891 - Macrocyclic compounds as antiviral agents
20090258894 - Fused aminopiperidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090258903 - Aminoethane sulfonamide orexin receptor antagonists
20090258913 - Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
20090258918 - Ep4 receptor agonist, compositions and methods thereof
20090253769 - Inhibitors of mammalian hdac 11 useful for treating hdac 11 mediated disorders
20090253769 - Inhibitors of mammalian hdac 11 useful for treating hdac 11 mediated disorders
20090253665 - Method of treatment of disease using an adenosine a1 receptor antagonist and an aldosterone inhibitor
20090253665 - Method of treatment of disease using an adenosine a1 receptor antagonist and an aldosterone inhibitor
20090253672 - Cathepsin cysteine protease inhibitors
20090253672 - Cathepsin cysteine protease inhibitors
20090253673 - Substituted pyrazoles as ghrelin receptor antagonists
20090253673 - Substituted pyrazoles as ghrelin receptor antagonists
20090253681 - Hiv integrase inhibitors
20090253681 - Hiv integrase inhibitors
20090253705 - Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists
20090253705 - Hydroxymethyl pyrrolidines as beta 3 adrenergic receptor agonists
20090253734 - Inhibitors of akt activity
20090253734 - Inhibitors of akt activity
20090253744 - Acylated piperidine derivatives as melanocortin-4 receptor modulators
20090253744 - Acylated piperidine derivatives as melanocortin-4 receptor modulators
20090253756 - Indole amide derivatives as ep4 receptor antagonists
20090253756 - Indole amide derivatives as ep4 receptor antagonists
20090246192 - 1d05 pcsk9 antagonists
20090247460 - Inhibitor of vascular endothelial cell growth factor
20090247499 - Sulfonylated piperazines as cannabinoid-1 receptor modulators
20090247504 - Indazole derivatives for treatment of alzheimer's disease
20090247514 - Spirolactam aryl cgrp receptor antagonists
20090247549 - Methods of using saha and bortezomib for treating cancer
20090247560 - Diaryl ketimine derivative
20090247565 - Tyrosine kinase inhibitors
20090247596 - Thiophenecarboxamide derivatives as ep4 receptor ligands
20090247770 - Process for making lactam tachykinin receptor antagonists

September 2009 - Merck And Co., Inc patents

20090239843 - Bridged diazepan orexin receptor antagonists
20090239849 - Aryl-fused spirocyclic compounds
20090239862 - Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators
20090239870 - Spirohydantoin aryl cgrp receptor antagonists
20090239876 - Substituted 4-hydroxypyrimidine-5-carboxamides
20090239905 - Piperidines and related compounds for the treatment of dementia
20090239946 - Pharmaceutical compositions of hdac inhibitors and chelatable metal compounds, and metal-hdac inhibitors chelate complexes
20090232795 - 1b20 pcsk9 antagonists
20090232795 - 1b20 pcsk9 antagonists
20090233992 - Hepatitis c virus vaccine
20090233992 - Hepatitis c virus vaccine
20090233896 - Inhibitors of checkpoint kinases
20090233897 - Potassium channel inhibitors
20090233896 - Inhibitors of checkpoint kinases
20090233897 - Potassium channel inhibitors
20090233936 - Fused aminopiperidines as dipeptidyl peptidase-4 inhibitors for the treatment or prevention of diabetes
20090233936 - Fused aminopiperidines as dipeptidyl peptidase-4 inhibitors for the treatment or prevention of diabetes
20090233947 - 2,3-substituted fused bicyclic pyrimidin-4(3h)-ones which modulating the function of the vanilloid -1 receptor (vr1)
20090233947 - 2,3-substituted fused bicyclic pyrimidin-4(3h)-ones which modulating the function of the vanilloid -1 receptor (vr1)
20090233967 - Crystalline forms of mc4r agonist and process for synthesis
20090233967 - Crystalline forms of mc4r agonist and process for synthesis
20090233977 - Method of treating atherosclerosis, dyslipidemias and related conditions
20090233977 - Method of treating atherosclerosis, dyslipidemias and related conditions
20090226464 - Immunoglobulins comprising predominantly a glcnacman3glcnac2 glycoform
20090226959 - Production of modified glycoproteins having multiple antennary structures
20090227598 - Ret tyrosine kinase inhibition
20090227638 - Novel pharmaceutical compounds
20090227674 - Combination methods fo saha and targretin for treating cancer
20090221679 - Novel hiv targets
20090221535 - Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae
20090221571 - Hiv integrase inhibitors
20090221592 - Dodecylsulfate salt of a dipeptidyl peptidase-iv inhibitor
20090221611 - Fused triazole tachykinin receptor antagonists
20090221669 - Disubstituted aniline compounds

August 2009 - Merck And Co., Inc patents

20090215101 - Hcv protease substrates
20090215101 - Hcv protease substrates
20090215101 - Hcv protease substrates
20090215101 - Hcv protease substrates
20090215101 - Hcv protease substrates
20090215775 - Sulphonamido-substituted cyclohexyl sulphones for treatment of cancer
20090215775 - Sulphonamido-substituted cyclohexyl sulphones for treatment of cancer
20090215775 - Sulphonamido-substituted cyclohexyl sulphones for treatment of cancer
20090215775 - Sulphonamido-substituted cyclohexyl sulphones for treatment of cancer
20090215775 - Sulphonamido-substituted cyclohexyl sulphones for treatment of cancer
20090215825 - Substituted pyrazoles, compositions containing such compounds and methods of use
20090215825 - Substituted pyrazoles, compositions containing such compounds and methods of use
20090215825 - Substituted pyrazoles, compositions containing such compounds and methods of use
20090215825 - Substituted pyrazoles, compositions containing such compounds and methods of use
20090215825 - Substituted pyrazoles, compositions containing such compounds and methods of use
20090209024 - Combinatorial dna library for producing modified n-glycans in lower eukaryotes
20090209024 - Combinatorial dna library for producing modified n-glycans in lower eukaryotes
20090209523 - Pyrrolo[1,2-a] pyrazin-1(2h)-one and pyrrolo[1,2-d][1,2,4]triazin-1(2h)-one derivatives as inhibitors of poly(adp-ribose)polymerase (parp)
20090209523 - Pyrrolo[1,2-a] pyrazin-1(2h)-one and pyrrolo[1,2-d][1,2,4]triazin-1(2h)-one derivatives as inhibitors of poly(adp-ribose)polymerase (parp)
20090209544 - Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090209544 - Aminotetrahydropyrans as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090209556 - Soluble guanylate cyclase activators
20090209556 - Soluble guanylate cyclase activators
20090209562 - Fused ring 4-oxopyrimidine derivative
20090209562 - Fused ring 4-oxopyrimidine derivative
20090209564 - Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
20090209564 - Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
20090209566 - Spirocyclic compounds
20090209566 - Spirocyclic compounds
20090209571 - Phenanthrene derivatives as mpges-1 inhibitors
20090209571 - Phenanthrene derivatives as mpges-1 inhibitors
20090202987 - Canis sphingosine 1-phosphate receptor isoform 2
20090203008 - Rapid method to determine inhibitor sensitivity of ns3/4a protease sequences cloned from clinical samples
20090203105 - Ura5 gene and methods for stable genetic integration in yeast
20090203684 - Tyrosine kinase inhibitors
20090203710 - Novel piperidine derivative
20090203903 - Thiazolyl mglur5 antagonists and methods for their use
20090203922 - Process for synthesizing 2-phenyl-1h-phenanthro[9,10-d]imidazole derivative
20090197299 - Method for assessing airborn microorganisms
20090197883 - Diphenyl substituted cycloalkanes, compositions containing such compounds and methods of use
20090197900 - Methods of treating heart failure and renal dysfunction in individuals with an adenosine a1 receptor antagonist
20090197904 - Sulphamides for treatment of cancer
20090197908 - Benzocycloheptapyridines as inhibitors of the receptor tyrosine kinase met

July 2009 - Merck And Co., Inc patents

20090191552 - Novel human acidic mammalian chitinase and use thereof
20090191578 - Canis sphingosine 1-phosphate receptor isoform 5
20090192139 - Cgrp receptor antagonists
20090192143 - Substituted diazepan orexin receptor antagonists
20090192155 - Identification of compounds suitable for treating ad
20090192158 - Methods for treating or preventing neoplasias
20090192174 - Novel aminopyridine derivatives having aurora a selective inhibitory action
20090186871 - Tyrosine kinase inhibitors
20090186919 - Piperidine derivatives for treatment of alzheimer's disease
20090186926 - Self-emulsifying formulations of cetp inhibitors
20090186928 - Novel crystalline forms of an inhibitor of 11-beta-hydroxysteroid dehydrogenase type 1
20090187028 - Process for preparing chiral dipeptidyl peptidase -iv inhibitor intermediates
20090181946 - Benzaepinones as sodium channel blockers
20090181994 - Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1
20090182001 - Inhibitors of checkpoint kinases
20090182002 - Tyrosine kinase inhibitors
20090182021 - Tricyclic beta-secretase inhibitors for the treatment of alzheimer's disease
20090176243 - Novel monkey gpr103 and monkey qrfp and method of evaluating compound by using gpr103
20090176263 - Canis sphingosine 1-phosphate receptort isoform 1
20090176757 - Bicyclic spirohydantoin cgrp receptor antagonists
20090176765 - Pyridinone and pyridazinone derivatives as inhibitors of poly (adp-ribose) polymerase (parp)
20090176789 - Diazaspirodecane orexin receptor antagonists
20090176836 - Cyclic ketal beta-secretase inhibitors for the treatment of alzheimer's disease
20090176854 - Pyrazole derivatives, compositions containing such compounds and methods of use
20090176859 - Cathepsin cysteine protease inhibitors
20090176861 - Cathepsin cysteine protease inhibitors
20090176986 - Process for the preparation of pyridine heterocycle cgrp antagonist intermediate
20090170159 - Production of glycoproteins with reduced o-glycosylation
20090170824 - Diarylsulfones as 5-ht2a antagonists
20090170828 - Azetidine derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090170830 - Tricyclic beta-secretase inhibitors for the treatment of alzheimer's disease
20090170863 - Acylated spiropiperidine derivatives as melanocortin-4 receptor modulators
20090170891 - Niacin receptor agonists, compositions containing such compounds and methods of treatment

June 2009 - Merck And Co., Inc patents

20090162377 - Immunoglobulins comprising predominantly a gal2glcnac2man3glcnac2 glycoform
20090162377 - Immunoglobulins comprising predominantly a gal2glcnac2man3glcnac2 glycoform
20090163379 - Eukaryotic cell display systems
20090163379 - Eukaryotic cell display systems
20090163544 - Use of nk-3 receptor antagonists for the treatment of nausea and vomiting
20090163544 - Use of nk-3 receptor antagonists for the treatment of nausea and vomiting
20090163559 - Estrogen receptor modulators
20090163559 - Estrogen receptor modulators
20090155298 - Matrix metalloproteinase 11 vaccine
20090155847 - Combinatorial dna library for producing modified n-glycans in lower eukaryotes
20090156579 - Combination of a dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension
20090156591 - Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (hdac) inhibitors
20090156617 - Tyrosine kinase inhibitors
20090156619 - Heterocycle substituted amide and sulfur amide derivatives as histone deacetylase (hdac) inhibitors
20090156825 - Fluorescent compounds that bind to histone deacetylase
20090148850 - Methods for identifying modulators of p2ry14
20090149398 - 6,11-3c-bicyclic 8a-azalide derivatives
20090149467 - Tyrosine kinase inhibitors
20090149470 - Novel aminopyridine derivatives having aurora a selective inhibitory action
20090149526 - Tetracyclic indole derivatives as antiviral agents
20090143413 - Thiazole derivatives as cxcr3 receptor modulators
20090143429 - Quinoline derivatives as neurokinin receptor antagonists

May 2009 - Merck And Co., Inc patents

20090136449 - Tetracyclic indole derivatives as antiviral agents
20090136525 - Immunoglobulins comprising predominantly a glcnacman3glcnac2 glycoform
20090136570 - Taste-masked tablets and granules
20090136979 - Class iia histone deacetylase (hdac) substrate
20090137529 - Substituted esters as cannabinoid-1 receptor modulators
20090137546 - Anti-hypercholesterolemic compounds
20090137548 - 1,3-oxazolidin-2-one derivatives useful as cetp inhibitors
20090137576 - Novel piperidine derivative
20090137587 - Phenylpyridone derivative
20090130709 - Endomannosidases in the modification of glycoproteins in eukaryotes
20090131419 - Sulphones which modulate the action of gamma secretase
20090131423 - Tyrosine kinase inhibitors
20090131451 - Diagnosis and treatment of type 2 diabetes and other disorders
20090131464 - Spirochromanone derivatives as acetyl coenzyme a carboxylase (acc) inhibitors
20090131465 - Synthesis and crystalline forms of melanocortin-4 receptor agonist
20090131472 - P38 kinase inhibiting agents
20090131494 - Non-nucleoside reverse transcriptase inhibitors
20090131664 - Method for producing 4(3h)-quinazolinone derivative
20090123538 - Angiotensin ii receptor antagonists
20090123571 - Method of treating men with testosterone supplement and 5alpha-reductase inhibitor
20090124000 - Recombinant vectors
20090124600 - N-alkyl-azacycloalkyl nmda/nr2b antagonists
20090124601 - Tartaric acid salts of a dipeptidyl peptidase-iv inhibitor
20090124603 - Diazepan orexin receptor antagonists
20090124641 - Mitotic kinesin inhibitors
20090124648 - Synthesis and crystalline forms of npy5 antagonist
20090124661 - Hcv ns3 protease inhibitors
20090124665 - Potassium channel inhibitors
20090124689 - Cetp inhibitors
20090124799 - Process for the preparation of caprolactam cgrp antagonist
20090117590 - Human calcium sensitive potassium channel beta3 subunit proteins, encoding nucleic acid and uses thereof
20090117616 - Methods for reducing or eliminating alpha-mannosidase resistant glycans for the production of glycoproteins
20090118200 - Proline bis-amide orexin receptor antagonists
20090118223 - Novel 2'-c-methyl and 4'c-methyl nucleoside derivatives
20090118291 - Histone deacetylase inhibitors
20090118296 - Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090118300 - Substituted imidazole 4-carboxamides as cholecystokinin-1 receptor modulators
20090118304 - 2-heteroaryl-substituted indole derivative

April 2009 - Merck And Co., Inc patents

20090111832 - Imidazolidinone compounds useful as beta-secretase inhibitors for the treatment of alzheimer's disease
20090111997 - Method of generating amorphous solid for water-insoluble pharmaceuticals
20090104210 - Peptide compounds for treating obesity and insulin resistance
20090104210 - Peptide compounds for treating obesity and insulin resistance
20090104210 - Peptide compounds for treating obesity and insulin resistance
20090104220 - Method to make a peptide-carrier conjugate with a high immunogenicity
20090104220 - Method to make a peptide-carrier conjugate with a high immunogenicity
20090104220 - Method to make a peptide-carrier conjugate with a high immunogenicity
20090105136 - Npy y2 agonist for use as therapeutic agent for disease accompanied by diarrhea
20090105136 - Npy y2 agonist for use as therapeutic agent for disease accompanied by diarrhea
20090105136 - Npy y2 agonist for use as therapeutic agent for disease accompanied by diarrhea
20090105210 - Bicyclic pyrimidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090105210 - Bicyclic pyrimidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090105210 - Bicyclic pyrimidines as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes
20090105219 - Spirolactam tricyclic cgrp receptor antagonists
20090105219 - Spirolactam tricyclic cgrp receptor antagonists
20090105219 - Spirolactam tricyclic cgrp receptor antagonists
20090105227 - Thienopyrroles as antiviral agents
20090105227 - Thienopyrroles as antiviral agents
20090105227 - Thienopyrroles as antiviral agents
20090105228 - Heterocyclic benzodiazepine cgrp receptor antagonists
20090105228 - Heterocyclic benzodiazepine cgrp receptor antagonists
20090105228 - Heterocyclic benzodiazepine cgrp receptor antagonists
20090105234 - Ep4 receptor agonist, compositions and methods thereof
20090105234 - Ep4 receptor agonist, compositions and methods thereof
20090105234 - Ep4 receptor agonist, compositions and methods thereof
20090105264 - Substituted nicotinamide compounds
20090105265 - Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin
20090105264 - Substituted nicotinamide compounds
20090105265 - Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin
20090105264 - Substituted nicotinamide compounds
20090105265 - Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin
20090105270 - Kinase inhibition and anticancer therapy
20090105270 - Kinase inhibition and anticancer therapy
20090105270 - Kinase inhibition and anticancer therapy
20090105284 - Aminocyclohexanes as dipeptidyl peptidase-iv for the treatment or prevention of diabetes
20090105284 - Aminocyclohexanes as dipeptidyl peptidase-iv for the treatment or prevention of diabetes
20090105284 - Aminocyclohexanes as dipeptidyl peptidase-iv for the treatment or prevention of diabetes
20090105310 - Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
20090105310 - Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
20090105310 - Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
20090105318 - Amidoethylthioether orexin receptor antagonists
20090105318 - Amidoethylthioether orexin receptor antagonists
20090105318 - Amidoethylthioether orexin receptor antagonists
20090105321 - Indole amide derivatives as ep4 receptot ligands
20090105321 - Indole amide derivatives as ep4 receptot ligands
20090105321 - Indole amide derivatives as ep4 receptot ligands
20090105479 - 4-oxo-1-3-substituted phenyl-1,4-dihydro-1,8-napthyridene-3-carboxamide phosphodiesterase-4 inhibitor and a method of preparing same
20090105479 - 4-oxo-1-3-substituted phenyl-1,4-dihydro-1,8-napthyridene-3-carboxamide phosphodiesterase-4 inhibitor and a method of preparing same
20090105479 - 4-oxo-1-3-substituted phenyl-1,4-dihydro-1,8-napthyridene-3-carboxamide phosphodiesterase-4 inhibitor and a method of preparing same
20090098155 - Peptide conjugate compositions and methods for the prevention and treatment of alzheimer's disease
20090098604 - Synthetic gene encoding human epidermal growth factor 2/neu antigen and uses thereof
20090099126 - Ribonucleoside cyclic acetal derivatives for the treatment of rna-dependent rna viral infection
20090099168 - Hiv integrase inhibitors
20090099200 - Azacyclohexane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090099226 - Quinoline derivatives as ep4 antagonists
20090099264 - Fluoroalkylamine derivatives as cathepsin inhibtors
20090092971 - Method for detecting p53 dysfunction, method for molecular diagnosis of cancer and method for evaluating compound effective in treating cancer
20090093020 - Methods for reducing or eliminating alpha-mannosidase resistant glycans in the production of glycoproteins
20090093444 - Cathepsin cysteine protease inhibitors
20090093527 - Azacyclopentane derivatives as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090093552 - Addition of lecithin as an antistatic agent for the crystallization processing of organic molecules
20090088431 - Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090088431 - Heteroaromatic compounds as inhibitors of stearoyl-coenzyme a delta-9 desaturase
20090088436 - P38 kinase inhibiting agents
20090088436 - P38 kinase inhibiting agents
20090088452 - Indole orexin receptor antagonists
20090088452 - Indole orexin receptor antagonists
20090088458 - N-(pyridin-4-yl)-2-phenylbutanamides as androgen receptor modulators
20090088458 - N-(pyridin-4-yl)-2-phenylbutanamides as androgen receptor modulators
20090088477 - Compounds and methods for leukotriene biosynthesis inhibition
20090088477 - Compounds and methods for leukotriene biosynthesis inhibition
20090089889 - Neuromedin u receptor subtype 1 deficient transgenic mice and uses thereof
20090089889 - Neuromedin u receptor subtype 1 deficient transgenic mice and uses thereof

March 2009 - Merck And Co., Inc patents

20090081645 - Method of assuming drug sensitivity to cdk4 inhibitor
20090081681 - Method for genetic selection of high-plasmid producing e. coli clones
20090082221 - Cross-species and multi-species display systems
20090082308 - Benzothiophene derivatives
20090082320 - Fluorinated 4-azasteroid derivatives as androgen receptor modulators
20090074890 - Substituted triazoles as sodium channel blockers
20090075319 - Method of detecting reactive metabolite
20090075869 - Hcv ns3 protease inhibitors
20090075979 - Cetp inhibitors
20090075998 - 2-(phenyl or heterocyclic)-1h-phenantrho[9,10-d]imidazoles as mpges-1 inhibitors
20090076101 - Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (hdac) inhibitors
20090068678 - Method for identifying modulators of noah10 useful for treating alzheimer's disease
20090069250 - Inhibitors of histone deacetylase
20090069283 - Potassium channel inhibitors
20090069284 - Substituted 3-alkyl and 3-alkenyl azetidine derivatives
20090069312 - Potassium channel inhibitors
20090069344 - Modulators of hcv replication
20090069376 - Vla-4 antagonists
20090069385 - Antidiabetic oxazolidinediones and thiazolidinediones
20090069391 - Benzothiophene hydroxamic acid derivatives
20090062269 - Niacin receptor agonists, compositions containing such compounds and methods of treatment
20090062280 - Ophthalmic compositions for treating ocular hypertension
20090062293 - 1,4-substituted piperazine derivatives
20090062297 - Hydroxyalkylarylamide derivatives
20090062302 - Jak2 tyrosine kinase inhibition
20090062327 - Inhibitors of akt activity
20090062349 - 1-hydroxycycloalkanecarboxamide derivatives

February 2009 - Merck And Co., Inc patents

20090054399 - Hiv integrase inhibitors
20090054408 - Monocyclic anilide spirolactam cgrp receptor antagonists
20090054423 - Niacin receptor agonists, compositions containing such compounds and methods of treatment
20090054440 - Quinoline derivatives as neurokinin receptor antagonists
20090054448 - Amino acid derivatives as histone deacetylase (hdac) inhibitors
20090054462 - Hydroisoindoline tachykinin receptor antagonists
20090054483 - Substituted quinolines as inhibitors of leukotriene biosynthesis
20090054506 - Glucagon receptor antagonist compounds, compositions containing such compounds and methods of use
20090054662 - Process for synthesizing a substituted pyrazole
20090047303 - Method for improving the immunogenicity of plasmodium antigens
20090047702 - Method for identifying modulators of keah6 useful for treating alzheimer's disease
20090048227 - Substituted-1-phthalazinamines as vr- 1 antagonists
20090048228 - Heterocycle derivatives as histone deacetylase (hdac) inhibitors
20090048239 - Therapeutic compounds
20090048248 - Octahydropyrano[3,4-c]pyrrole tachykinin receptor antagonists
20090048276 - Inhibitors of fatty acid synthase (fas)
20090048283 - Salt of an androgen receptor modulator
20090048308 - Vla-4 antagonists
20090042854 - Hexahydro-3h-pyrrolizin-3-ones useful as tachykinin receptor antagonists
20090042892 - Cetp inhibitors
20090042926 - Niacin receptor agonists, compositions containing such compounds and methods of treatment
20090042944 - Potassium channel inhibitors
20090042954 - 2-(aryl)azacyclylmethyl carboxylates, sulfonates, phosphonates, phosphinates and heterocycles as s1p receptor antagonists
20090042966 - Mitotic kinesin inhibitors
20090035277 - Hepatitis c virus nucleic acid vaccine
20090036443 - Thienopyrroles as antiviral agents
20090036503 - Triazole derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase-1



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