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Medical composition for protuberance of epitheliumRelated Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Designated Organic Active Ingredient Containing (doai), O-glycoside, PolysaccharideMedical composition for protuberance of epithelium description/claimsThe Patent Description & Claims data below is from USPTO Patent Application 20060105991, Medical composition for protuberance of epithelium. Brief Patent Description - Full Patent Description - Patent Application Claims
BACKGROUND OF THE PRESENT INVENTION [0001] 1. Field of the Invention [0002] The present invention relates to a medical composition for protuberance of epithelium, which comprises a solution comprising a polysaccharide or a salt thereof, wherein the solution has predetermined properties. Also, the present invention relates to a syringe filled with the medical composition. [0003] 2. Brief Description of the Background Art [0004] When it is necessary to apply a medical treatment to epithelium, e.g., when it is necessary to excise epithelium, the treatment can sometimes be facilitated by distending (elevating) the epithelium. [0005] For example, endoscopic mucosal resection (hereinafter also referred to as "EMR") is a method in which mucosa, such as digestive tracts, changed into a morbid state is excised by an operation using an endoscope without ventrotomy, which is carried out by excising the region of mucosa changed into a morbid state by hooking the region with a wire loop attached to the tip of the endoscope. In order to improve efficiency, workability and safety of the operation, attempts have been made to develop a method for distending (elevating) a mucosa region changed into a morbid state by injecting a high molecular polymer solution into a lower layer of the mucosa region changed into a morbid state. [0006] Gastrointestinal Endoscopy, 50(2), pp. 251-256 (1999) discloses that 1.0% sodium hyaluronate solution was used for elevation of mucosa in EMR, and discloses that it was administered using a disposable syringe. [0007] Also, the same reference discloses that "a hypertonic saline and epinephrine" and "a hypertonic saline with epinephrine and 50% glucose" have been conventionally used for elevation of mucosa in EMR. [0008] Furthermore, Gastrointestinal Endoscopy, 50(5), pp. 701-704 (1999) discloses that a 0.5% sodium hyaluronate solution containing a small amount of indigocarmine dye was used for elevation of mucosa in EMR, and that it was administered using a 5 ml capacity syringe. [0009] Although EMR is an operation using an endoscope, a part of vital tissues must be removed and, when burden to patients is taken into consideration, it is preferable carry out the operation as quickly and securely as possible. Thus, great concern has been directed toward the development of a composition for quickly and securely carrying out medical treatments of epithelium, including the EMR. SUMMARY OF THE INVENTION [0010] An object of the present invention is to provide a composition for more quickly and securely carrying out medical treatments of epithelium, more particularly, a composition which can quickly carry out injection of a solution in treatment of epithelium, can keep high protuberance (elevation) of epithelium for a certain period of time, can exclude the necessity for additionally injecting a solution during the treatment of epithelium as small as possible, and can improve workability in treatment of epithelium. [0011] Furthermore, an object of the present invention is to provide a syringe which is quickly used for the protuberance (elevation) of epithelium in treatment of epithelium. [0012] These and other objects of the present invention have been accomplished by a medical composition for protuberance (elevation) of epithelium, which comprises a solution comprising a polysaccharide or a medically acceptable salt thereof, wherein the solution has a viscosity of: (1) from 50 to 500 mPas at a shear rate of from 7.7 to 10.0 s.sup.-1; (2) from 45 to 300 mPas at a shear rate of from 19.2 to 20.0 s.sup.-1; and (3) from 40 to 200 mPas at a shear rate of from 38.3 to 40.0 s.sup.-1, [0013] when measured using a rotational viscometer at 25.degree. C. (hereinafter referred to as "composition of the present invention"). [0014] Furthermore, these and other objects of the present invention have been accomplished by a syringe filled with the composition of the present invention (hereinafter referred to as "syringe of the present invention"). [0015] Moreover, these and other objects of the present invention have been accomplished by a method for resecting epithelium, which comprises: [0016] administering an effective amount of the medical composition to under epithelium to thereby obtain protuberance of the epithelium; and [0017] resecting the protuberance. DETAILED DESCRIPTION OF THE INVENTION [0018] As a result of intensive studies carried out in order to solve the above problems, the present inventors have found that when a solution having specified properties is used, the solution can be injected easily even through a thin catheter and needle and also high protuberance of epithelium can be kept for a certain period of time. Thus, the present invention has been completed. Continue reading about Medical composition for protuberance of epithelium... Full patent description for Medical composition for protuberance of epithelium Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Medical composition for protuberance of epithelium patent application. ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. Start now! - Receive info on patent apps like Medical composition for protuberance of epithelium or other areas of interest. ### Previous Patent Application: Food for improving arthritis Next Patent Application: Sulfur-containing phospholipid derivatives Industry Class: Drug, bio-affecting and body treating compositions ### FreshPatents.com Support Thank you for viewing the Medical composition for protuberance of epithelium patent info. 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