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Long lasting waterproof sunscreen comprising metal oxide and peptide conditionerRelated Patent Categories: Drug, Bio-affecting And Body Treating Compositions, Topical Sun Or Radiation Screening, Or Tanning PreparationsLong lasting waterproof sunscreen comprising metal oxide and peptide conditioner description/claimsThe Patent Description & Claims data below is from USPTO Patent Application 20070274931, Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner. Brief Patent Description - Full Patent Description - Patent Application Claims
CROSS-REFERENCE TO RELATED APPLICATIONS [0001] This application is a continuation-in-part of application Ser. No. 11/011,670 filed on Dec. 14, 2004 which is a continuation-in-part of application Ser. No. 10/737,357, filed Dec. 16, 2003 which are both incorporated herein by reference in their entireties. [0002] This application is a continuation-in-part of application Ser. No. 10/935,642 filed on Sep. 7, 2004 which is incorporated herein by reference in its entirety. FIELD OF THE INVENTION [0003] The present invention relates to sunscreen compositions. More specifically, the invention relates to sunscreen screen compositions based upon inorganic metal oxides and skin-binding, peptides. BACKGROUND OF THE INVENTION [0004] Certain metal oxides, such as titanium dioxide and zinc oxide, are known for their sunscreen properties. Titanium dioxide has low toxicity and is non-irritating to the skin. [0005] Nanostructured particles and materials are currently attracting considerable attention. The small size of nanoparticles (generally used to indicate particles less than 100 nm), which can be responsible for the different properties (electronic, optical, electrical, magnetic, chemical, and mechanical) of nanoparticles and nanostructured materials with respect to the bulk material, makes them suitable for new industrial applications. In many of these new applications, it is imperative to provide and maintain the particles and materials well dispersed in a fluid medium, such as water, organic solvent, wax, oil, polymer or mixtures of these. [0006] Titanium dioxide (TiO2) nanoparticles are substantially transparent to visible light, that is, are transparent, but reflect, scatter and absorb ultraviolet light. The nanoparticles, in contrast to pigment-sized titanium dioxide particles, can be beneficial in sunscreen formulations where transparency of the formulation is desirable. [0007] A major problem with current skin care compositions is that they lack the required durability for long-lasting effects. For this reason, there have been attempts to enhance the binding of the skin care agent to the skin. [0008] A need exists for sunscreen formulations that provide improved durability for long lasting effects. SUMMARY OF THE INVENTION [0009] In a first embodiment of the invention, the disclosure provides a sunscreen formulation comprising: [0010] (a) a peptide-based metal oxide sunscreen agent, and [0011] (b) a fluid vehicle. [0012] The peptide-based skin conditioner may be a diblock composition having the general structure (SBP).sub.n-SSA, wherein SBP is a skin-binding peptide, SSA is a metal oxide sunscreen agent and n ranges from 1 to about 50, specifically n ranges from about 1 to about 10. [0013] In one embodiment of the invention, the peptide-based metal oxide sunscreen agent may be a triblock composition having the general structure [(SBP).sub.m-S].sub.n-SSA, wherein SBP is a skin-binding peptide; S is a spacer having first and second ends; SSA is a metal oxide sunscreen agent; m ranges from 1 to about 50; and n ranges from 1 to about 500, specifically n ranges from about 1 to about 10. [0014] In one embodiment of the invention, the metal oxide sunscreen agent comprises at least one metal oxide selected from the group consisting of titanium dioxide, zinc oxide, cerium oxide and iron oxide, more typically from the group of titanium dioxide and zinc oxide, and still more typically titanium dioxide. The metal oxide can be in the pigment size range or in the nanoparticle size range. [0015] The metal oxide sunscreen agent can be prepared by a process comprising: [0016] (a) forming a slurry of metal oxide; [0017] (b) contacting the slurry of metal oxide with a densifying agent; [0018] (c) contacting the slurry with a source of a metal oxide selected from the group consisting of a source of alumina, a source of silica or both to form a treated metal oxide; and [0019] (d) recovering the treated metal oxide formed in step (c). [0020] Typically, the metal oxide prepared by this process is titanium dioxide, especially titanium dioxide nanoparticles. The metal oxide particles prepared by this process have been found to have a high photo stability and/or high chemical stability. In addition the nanoparticles have a reduced tendency to form agglomerates when formulated into sunscreen composition. [0021] The metal oxide nanoparticles may be prepared by any processes which are well known in the art including but not limited to plasma processes or a sol gel process. [0022] In a second embodiment, the invention provides a process for preparing a sunscreen formulation comprising mixing a peptide-based metal oxide sunscreen agent and a fluid vehicle. BRIEF DESCRIPTION OF THE FIGURES AND SEQUENCE DESCRIPTIONS [0023] The invention can be more fully understood from the following detailed description, and the accompanying sequence descriptions, which form a part of this application. [0024] The following sequences conform with 37 C.F.R. 1.821-1.825 ("Requirements for Patent Applications Containing Nucleotide Sequences and/or Amino Acid Sequence Disclosures--the Sequence Rules") and consistent with World Intellectual Property Organization (WIPO) Standard ST.25 (1998) and the sequence listing requirements of the EPO and PCT (Rules 5.2 and 49.5(a-bis), and Section 208 and Annex C of the Administrative Instructions). The symbols and format used for nucleotide and amino acid sequence data comply with the rules set forth in 37 C.F.R. .sctn.1.822. [0025] SEQ ID NOs:1-8 are the amino acid sequence of skin-binding peptides. Continue reading about Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner... Full patent description for Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner patent application. ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. 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