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Jan Kajstura patents

Recent bibliographic sampling of Jan Kajstura patents listed/published in the public domain by the USPTO (USPTO Patent Application #,Title):



08/22/13 - 20130216508 - Human lung stem cells and uses thereof
Embodiments of the invention relate to human stem cells and their therapeutic use in the treatment and/or prevention of lung diseases. Provided herein are compositions comprising c-kit positive human lung stem cells and methods of preparing and using c-kit positive human lung stem cells for the treatment and/or prevention of...
Inventors: Piero Anversa, Mark Perrella, Annarosa Leri, Jan Kajstura (The Brigham And Women's Hospital, Inc.)

01/17/13 - 20130017176 - Compositions comprising cardiac stem cells overexpressing specific micrornas and methods of their use in repairing damaged myocardium
The invention provides compositions comprising modified stem cells containing a transgene that affects the expression of at least one gene that inhibits or promotes cardiomyogenesis. In particular, the invention discloses compositions comprising cardiac stem cells, wherein said cardiac stem cells comprise a transgene encoding a microRNA. The compositions of the...
Inventors: Toru Hosoda, Piero Anversa, Annarosa Leri, Jan Kajstura (New York Medical College)

12/20/12 - 20120321595 - Treatment of heart disease
Disclosed herein are methods, compositions and kits for treating cardiac stem cells to be administered to a subject in need thereof, e.g., with a damaged myocardium. The methods, composition and kits of the invention can be used to treat cardiovascular diseases such as heart failure, myocardial infarction and an age-related...
Inventors: Piero Anversa, Jan Kajstura, Annarosa Leri (The Brigham And Women's Hospital, Inc.)

11/15/12 - 20120288481 - Treatment of heart disease
Disclosed herein are methods, compositions and kits for treating cardiac stem cells to be administered to a subject in need thereof, e.g., with a damaged myocardium. The methods, composition and kits of the invention can be used to treat cardiovascular diseases such as heart failure, myocardial infarction and an age-related...
Inventors: Piero Anversa, Jan Kajstura, Annarosa Leri, Polina Goihberg (The Brigham And Women's Hospital, Inc.)

08/16/12 - 20120207714 - Compositions comprising vascular and myocyte progenitor cells and methods of their use
The invention provides compositions of adult cardiac vascular progenitor cells (VPCs) and adult cardiac myocyte progenitor cells (MPCs) useful for the treatment of various cardiac conditions. The invention also encompasses methods of generating a biological bypass, repairing damaged myocardium, and treating or preventing hypertensive cardiomyopathy and heart failure with the...
Inventors: Piero Anversa, Annarosa Leri, Jan Kajstura (New York Medical College)

05/26/11 - 20110123500 - Methods of isolating non-senescent cardiac stem cells and uses thereof
The invention describes the isolation and methods of use of a non-senescent pool of adult cardiac stem cells. In particular, a subset of adult cardiac stem cells with superior regenerative capacity is disclosed. Such cells were found to have immortal DNA. Compositions comprising the non-senescent stem cells are also described....
Inventors: Piero Anversa, Annarosa Leri, Jan Kajstura (New York Medical College)

12/24/09 - 20090317369 - Compositions comprising cardiac stem cells overexpressing specific micrornas and methods of their use in repairing damaged myocardium
The invention provides compositions comprising modified stem cells containing a transgene that affects the expression of at least one gene that inhibits or promotes cardiomyogenesis. In particular, the invention discloses compositions comprising cardiac stem cells, wherein said cardiac stem cells comprise a transgene encoding a microRNA. The compositions of the...
Inventors: Inventors: Piero Anversa, Annarosa Leri, Jan KajsturaPiero Anversa, Annarosa Leri, Jan Kajstura, Toru Hosoda, Piero Anversa, Annarosa Leri, Jan Kajstura

07/16/09 - 20090180998 - Methods of isolating non-senescent cardiac stem cells and uses thereof
The invention describes the isolation and methods of use of a non-senescent pool of adult cardiac stem cells. Methods for repairing aged myocardium or damaged myocardium using the isolated non-senescent adult cardiac stem cells are also disclosed. In addition, the invention describes a method for preventing or treating heart failure....
Inventors: Piero Anversa, Annarosa Leri, Jan Kajstura

07/02/09 - 20090169525 - Methods of reducing transplant rejection and cardiac allograft vasculopathy by implanting autologous stem cells
The invention provides novel methods of reducing transplant rejection and cardiac allograft vasculopathy in humans by employing the implantation of autologous progenitor cells into the transplanted donor heart. The autologous progenitor cells can be vascular progenitor cells (VPCs) and/or myocyte progenitor cells (MPCs) isolated from the recipient's explanted heart. Alternatively,...
Inventors: Piero Anversa, Annarosa Leri, Jan Kajstura

06/25/09 - 20090162329 - Compositions comprising hdac inhibitors and methods of their use in restoring stem cell function and preventing heart failure
The invention provides compositions of histone deacetylase (HDAC) inhibitors and progenitor cells useful for treating heart failure in a subject. The invention also provides methods of restoring progenitor cell function to aged progenitor cells and methods for enhancing progenitor cell proliferation and/or differentiation using HDAC inhibitors....
Inventors: Piero Anversa, Annarosa Leri, Jan Kajstura

06/11/09 - 20090148421 - Compositions comprising vascular and myocyte progenitor cells and methods of their use
The invention provides compositions of adult cardiac vascular progenitor cells (VPCs) and adult cardiac myocyte progenitor cells (MPCs) useful for the treatment of various cardiac conditions. The invention also encompasses methods of generating a biological bypass, repairing damaged myocardium, and treating or preventing hypertensive cardiomyopathy and heart failure with the...
Inventors: Piero Anversa, Annarosa Leri, Jan Kajstura

The Brigham And Women's Hospital, Inc., New York Medical College

Archived*
(*May have duplicates - we are upgrading our archive.)

20090162329 - Compositions comprising hdac inhibitors and methods of their use in restoring stem cell function and preventing heart failure
20090162329 - Compositions comprising hdac inhibitors and methods of their use in restoring stem cell function and preventing heart failure
20090148421 - Compositions comprising vascular and myocyte progenitor cells and methods of their use


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The bibliographic references displayed about Jan Kajstura's patents are for a recent sample of Jan Kajstura's publicly published patent applications. The inventor/author may have additional bibliographic citations listed at the USPTO.gov. FreshPatents.com is not associated or affiliated in any way with the author/inventor or the United States Patent/Trademark Office but is providing this non-comprehensive sample listing for educational and research purposes using public bibliographic data published and disseminated from the United States Patent/Trademark Office public datafeed. This information is also available for free on the USPTO.gov website. If Jan Kajstura filed recent patent applications under another name, spelling or location then those applications could be listed on an alternate page. If no bibliographic references are listed here, it is possible there are no recent filings or there is a technical issue with the listing--in that case, we recommend doing a search on the USPTO.gov website.

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