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12/20/07 - USPTO Class 435 |  86 views | #20070292933 | Prev - Next | About this Page  435 rss/xml feed  monitor keywords

Inhibitors of serine proteases, particular hcv ns3-ns4a protease

USPTO Application #: 20070292933
Title: Inhibitors of serine proteases, particular hcv ns3-ns4a protease
Abstract: The present invention relates to compounds that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing these compounds. (end of abstract)



Agent: Vertex Pharmaceuticals Inc. - Cambridge, MA, US
Inventors: Janos Pitlik, Kevin M. Cottrell, Luc J. Farmer, Robert B. Perni, Lawrence F. Courtney, John H. van Drie, Mark A. Murcko
USPTO Applicaton #: 20070292933 - Class: 435184000 (USPTO)

Related Patent Categories: Chemistry: Molecular Biology And Microbiology, Enzyme (e.g., Ligases (6. ), Etc.), Proenzyme; Compositions Thereof; Process For Preparing, Activating, Inhibiting, Separating, Or Purifying Enzymes, Enzyme Inactivation By Chemical Treatment

Inhibitors of serine proteases, particular hcv ns3-ns4a protease description/claims


The Patent Description & Claims data below is from USPTO Patent Application 20070292933, Inhibitors of serine proteases, particular hcv ns3-ns4a protease.

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