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Infant formulaInfant formula description/claimsThe Patent Description & Claims data below is from USPTO Patent Application 20080125346, Infant formula. Brief Patent Description - Full Patent Description - Patent Application Claims
FIELD OF THE INVENTION
The present invention relates to a nutritional composition for feeding infants, containing fat, protein, carbohydrate, a nucleotide component and to the use thereof. BACKGROUND OF THE INVENTIONBreastfeeding optimally supports the development of the infant and protects against infections and allergies. However, not all infants are in the position to receive human milk. It is therefore a continuing aim to provide infant formula, which simulates the functions of human milk. In addition to the desired compositional similarity between infant formula and human milk, it is also particularly desirable to mimic the protective effects of human milk, in particular protection against allergies and infections. SUMMARY OF THE INVENTIONThe present inventors have recognized that the molecular structure and density of charge of nucleotides is an important factor for the bioactivity of nucleotide components, particularly nucleotides. It was found that by combining nucleotide components with negatively charged non-protein components the bioactive effects of the nucleotide component in nutritional formulations may be enhanced significantly. Hence, the present invention provides a nutritional composition containing a nucleotide component; and a non-proteinaceous negatively charged, glycan or glycoconjugate component with a molecular weight between 200 and 20.000 dalton (hereinafter referred to as NCC). The present nutritional composition is particularly effective in: Enhancing immune cell proliferation, improving the development of T-lymphocyte sub populations, and enhancing the antibody response; Stimulating the development of the immune system of neonates Stimulating the development of the nerve system of neonates Stimulating the neonatal development and repair of the gastrointestinal tract after surgery or disease Modulating the gutflora, Stimulating the synthesis of long-chain polyunsaturated fatty acids Providing anti-infective, antibacterial/viral effects Without wishing to be bound by theory, the improved activity is believed to be the result of an improved presentation and delivery of the negatively charged nucleotide component to the epithelial cells, due to interaction of the NCC and the nucleotide component e.g. via hydrogen and salt bridges. The biological active molecular anionic charge of nucleotides is condensed and the molecular distribution of charge is beneficially altered. The present nutritional composition can be even further improved by combining the nucleotide component and NCC with bivalent cations, preferably calcium and/or zinc. The cation will increase proximity of the nucleotide component and the NCC in a liquid environment (e.g. the intestinal tract) by formation of hydrogen/salt bridges, thereby further increasing the interactive effects between the NCC and the nucleotide components. Continue reading about Infant formula... Full patent description for Infant formula Brief Patent Description - Full Patent Description - Patent Application Claims Click on the above for other options relating to this Infant formula patent application. Patent Applications in related categories: 20090286713 - Collagen receptor i-domain binding modulators - The present invention relates to a refined and detailed molecular model of the α2⊕1 integrin I-domain, especially the MIDAS and to the use of such a model for designing novel integrin modulators, especially α2β1 integrin modulators. The present invention further relates to novel α2β1 I-domain modulators, which are of therapeutic ... 20090286714 - Novel molecules of the card-related protein family and uses thereof - Novel CARD-9, CARD-10, or CARD-11 polypeptides, proteins, and nucleic acid molecules are disclosed. In addition to isolated CARD-9, CARD-10, or CARD-11 proteins, the invention further provides CARD-9, CARD-10, or CARD-11, fusion proteins, antigenic peptides and anti-CARD-9, CARD-10, or CARD-11 antibodies. The invention also provides CARD-9, CARD-10, or CARD-11 nucleic acid ... ###  How KEYWORD MONITOR works... a FREE service from FreshPatents1. Sign up (takes 30 seconds). 2. Fill in the keywords to be monitored. 3. Each week you receive an email with patent applications related to your keywords. Start now! - Receive info on patent apps like Infant formula or other areas of interest. ### Previous Patent Application: Branched polyalkylene glycols Next Patent Application: Polymer-based sustained release device Industry Class: Drug, bio-affecting and body treating compositions ### FreshPatents.com Support Thank you for viewing the Infant formula patent info. IP-related news and info Results in 0.1239 seconds Other interesting Feshpatents.com categories: Tyco , Unilever , Warner-lambert , 3m 174 |
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